1.Data curation and its application in special libraries
Chinese Journal of Medical Library and Information Science 2014;(9):41-44
After the concept of data curation and its application in foreign countries were described , the key points of data curation for data service in special libraries and related problems were analyzed according to the overall needs and changes of users in special libraries.
2.Quality Standard for Chuipencao Tablets
Ping WEN ; Xiaowei HUANG ; Yifen YE
China Pharmacist 2014;(9):1454-1456
Objective:To establish the quality standard for Chuipencao tablets. Methods:Sedum sarmentosum Bunge was identi-fied by TLC. Quercetin, kaempferol and isorhamnetin were determined by HPLC. Results: The method of TLC was highly specific. The linearity was obtained within the range of 4.94-98.82 μg·ml-1(r =0.999 9) for quercetion, 4.94-98.82 μg·ml-1(r =0.999 9) for kaempferol and 1.07-21.36 μg·ml-1(r=0.999 9) for isorhamnetion. The average recovery was 103.1%(RSD =2. 2%,n=6), 100. 6%(RSD=2. 0%,n=6) and 100. 1%(RSD=2. 0%,n=6), respectively. Conclusion: The method is accu-rate with good reproducibility, which can be used as the quality control for Chuipencao tablets.
3.Application of modified flowchart of items supply in preoperational articles in the operating room
Fengqing YE ; Jinhuan LI ; Tianxi YANG ; Yang HUANG ; Xuexian WEN
Modern Clinical Nursing 2015;(4):52-54
Objective To discussed application effect of modified flowchart of preoperational articles in the operating room. Methods A group for the reconstructed flowchart was set up to look into the problems of traditional flowchart for articles preparation and then have the flowchart modified upon the found problems. The duration for article preparation and the flaw rate were compared between pre-and post-modification. Result The duration for preparation after modification was significantly shorter than that before modification and the flaw rate was significantly lower as well (P<0.001). Conclusion The modified flowchart for article preparation in the operation room can reduce the flaw rate and shorten the duration for article preparation, thus ensuring smooth operation.
4.Application of CDP technology in protecting data in libraries
Xin SONG ; Wen HUANG ; Juntao MA ; Ye SU
Chinese Journal of Medical Library and Information Science 2014;(8):76-80
After the meaning, features and application models of CDP technology were described, its application in protecting data in libraries was studied with Medical Library of Chinese PLA as an example, showing that CDP technology can effectively protect the data, improve their safety, and insure the stable operation of professional sys-tems in Medical Library of Chinese PLA.
5.Review of key technologies used in mobile reading service of library
Juntao MA ; Wen HUANG ; Xin SONG ; Ye SU
Chinese Journal of Medical Library and Information Science 2014;(3):34-38
After the key technologies used in mobile reading service of library were compared , the authors pointed out that copyright and privacy protection were the major issues challenging the mobile reading service of library.Its development was prospected .
6.Implementation of information pushing function in mobile library using Drupal+PhoneGap
Ye SU ; Wen HUANG ; Xin SONG ; Juntao MA
Chinese Journal of Medical Library and Information Science 2014;(5):76-80
Drupal, a powerful content management system and content management framework, can provide a visiting interface for the mobile terminal equipments , especially the interface for the mobile APP program .How to imple-ment the information pushing function in mobile library using Drupal+PhoneGap was described by constructing the APP program model for information pushing and browsing in mobile library as an example.
7.Correlation of neutrophil gelatinase - associated lipocalin with dialysis adequacy,microinflammation and iron metabolism in maintenance hemodialysis patients
Zhanyuan LI ; Wen HUANG ; Yu ZHENG ; Hanyang YE ; Lingwei JIN ; Bairu YE ; Zhihong ZHOU
Chinese Journal of Nephrology 2012;28(8):597-601
Objective To examine the correlation of serum neutrophil gelatinase-associated lipocalin (NGAL) with dialysis adequacy,microinflammatory state and iron metabolism,and to assess the value of NGAL in identifying the dialysis adequacy in maintenance hemodialysis (MHD) patients.Methods A total of 150 MHD patients and 50 healthy control people were enrolled in the study.Clinical data were collected and serum NGAL,CRP,transferrin saturation,serum ferritin were measured.MHD patients were divided into adequacy group and non-adequacy group according to spKt/V value.Serum NGAL between two groups was compared and correlation of NGAL with spKt/V,inflammatory factors,and other clinical indexes was examined by Pearson,multivariate regression Logistic model and area under curve (AUC) of ROC.MHD patients were followed up for 3 months.Similar correlation analysis was carried out before and after follow up between two groups.Results Serum NGAL of MHD patients was higher compared to healthy people [(445.45±50.34) μg/L vs (50.02 ±6.45) μg/L].Among 150 MHD patients,95 were classified into adequacy group,while 55 into non-adequacy group according to spKt/V value.Serum NGAL was significantly higher in adequacy group as compared to non-adequacy group [(589.14±56.34) μg/L vs (360.13±46.23) μg/L,P<0.05].Serum NGAL was positively correlated to spKt/V,CRP,TSAT [r=0.652,0.825,0.785,all P<0.05],but not to serum ferritin.Serum NGAL was also correlated to spKt/V,CRP,TSAT by multivariate regression Logistic model.AUC showed that NGAL level could reflex the condition of dialysis adequacy.During the follow up,all adequacy patients remained the same adequacy status.Thirty-eight out of 55 non-adequacy patients were qualified for complete adequacy after intervention.The serum NGAL before and after intervention was (368.14±56.21) μg/L and (360.56±46.23) μg/L respectively without significant difference.Conclusions Serum NGAL is obviously higher in MHD patients with dialysis adequacy compared to those without dialysis adequacy.Serum NGAL is positively correlated to spKt/V,CRP,TSAT.NGAL can reflex the condition of dialysis adequate in MHD patients.
8.Phenols from Vitex negundo
Ting WEN ; Jie HUANG ; Xiaojun HUANG ; Chunlin FAN ; Ying WANG ; Wencai YE
Chinese Traditional Patent Medicine 2017;39(7):1431-1434
AIM To study the phenols from Vitex negundo Linn..METHODS The ethyl acetate fraction of 70% ethanol extract from V.negundo was isolated and purified by silica,Sephadex LH-20 and ODS column,then the structures of obtained compounds were identified by spectral data.RESULTS Seven compounds were isolated and identified as luteolin-4'-O-β-D-glucopyranoside (1),isoorientin 6-O-caffeate (2),3,4,5-tricaffeoyl quinic acid (3),(+)-pinoresinol-4-O-β-D-glucoside (4),methyl isoferuloyl-7-(3,4-dihydroxyphenyl) lactate (5),benzyl 7-O-β-D-glucoside (6) and oresbiusin A (7).CONCLUSION All the compounds are isolated from this plant for the first time,and compounds 1,3,5-7 are first isolated from genus Vitex.
9.A new flavonoid glycoside from leaves of Eucalyptus robusta.
Xi-feng GUAN ; Qian-yi GUO ; Xiao-jun HUANG ; Ying WANG ; Wen-cai YE
China Journal of Chinese Materia Medica 2015;40(24):4868-4872
A new flavonoid glycoside, (-)-2S-8-methyl-5,7,4'-trihydroxyflavanone-7-O-β-D-glucopyranoside (1), along with five known ones, quercetin-3-O-(2"-galloyl)-α-L-arabinoside (2), kaempferol-3-O-α-L-arabinoside (3), guaijaverin (4), trifolin (5) and hyperin (6), was isolated from the leaves of Eucalyptus robusta. Their structures with absolute configurations were elucidated by NMR, HR-ESI-MS, CD spectra data and physicochemical methods. In addition, 2-6 were isolated from E. robusta for the first time.
Eucalyptus
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chemistry
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Flavonoids
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chemistry
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isolation & purification
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Glycosides
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chemistry
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isolation & purification
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Plant Leaves
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chemistry
10.Evaluation of outcome and cerebral protective effects for ketogenic diet therapy to status epilepticus
Jialun WEN ; Jianxiang LIAO ; Xianling MENG ; Sufang LIN ; Tieshuan HUANG ; Jinghua YE
Chinese Pediatric Emergency Medicine 2015;22(9):614-616
Objective To explore the efficacy of ketogenic diet( KD) in the treatment of status epi-lepticus( SE) and whether KD could protect the brain,and propose a new thought on SE patients′reasonably individualized treatment, brain protection and prognosis improvement. Methods From Sep 2013 to Jan 2015,all the patients diagnosed as SE were advised to apply KD treatment; the patients who refused KD treatment were included in the control group,while the patients who accepted KD treatment were included in the treatment group. Based on the SE treatment principles,the control group applied traditional anti-convulsive therapy,while the treatment group applied traditional therapy combined with KD treatment. Before the treat-ment and after the epilepsy control,the patients′ serum was collected to test neuron specific enolase( NSE) and S100βlevels,and the duration of epilepsy control was recorded. Results The treatment group included a total of 10 patients; 3 patients had a good efficacy and obtained seizure-free after the treatment; clinical seizures declined significantly in 6 patients. The treatment group′s overall response rate was 9/10,which was higher than that of the control group(5/8)(P<0. 01). The treatment group′s duration to gain efficacy was shorter than that of the control group[(5. 2 ± 2. 9) d vs. (9. 8 ± 1. 5) d,P<0. 01]. After the treatment,the patients′NSE and S100β in both groups were significantly decreased than those before the treatment ( P<0. 001 or P<0. 05). After the treatment,the serum NSE and S100β of the patients in the treatment group were lower than those in the control group,with statistically significant difference(P<0. 05). Conclusion Frequent epileptic seizures and SE would impair the patient′s brain. Controlling the epileptic seizures actively could lower the severity of brain injury. KD could effectively control the epileptic seizure and had neuropro-tective effects.