OBJECTIVETo study the alkaloidial constituents of the leaves of uncaria hirsuta.

METHODSome chromatographic methods were applied to isolate pure compounds and their structures were elucidated by spectroscopic methods.

RESULTEleven compounds were isolated and identified as 19-epi-3-iso-ajmalicine (1), 3-isoajmalicine (2), harman (3), mitraphylline (4), isomitraphylline (5), isorhynchophylline (6), corynoxine (7), rhynchophylline (8), isomitraphyllic acid (9), uncarine A (10) and uncarine B (11).

CONCLUSIONCompounds 1-9 were firstly isolated from this plant.

Alkaloids ; chemistry ; Drugs, Chinese Herbal ; chemistry ; Plant Leaves ; chemistry ; Uncaria ; chemistry

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