1.The surgical staging and operative treatment of primary tumors of cervical spine
Jianru XIAO ; Lianshun JIA ; Wen YUAN
Chinese Journal of Orthopaedics 2000;0(11):-
Objective To investigate the clinical characteristics, surgical staging of primary tumors of cervical spine, the effects of different surgical approach and operative method. Methods The location, characteristics,surgical staging, clinical manifestation of tumors, different operative approach and opertative methods were described respectively. Surgical staging of the tumors in 45 cases was divided into four stages: 10 cases in stageⅠ,11 cases in stage Ⅱ, 9 cases in stage Ⅲ, 15 cases in stage Ⅳ. Eleven cases were treated with intracapsule excision, 18 cases by marginal excision, 15 cases by wide excision. Results The following up period lasted from 6 months to 10 years(average 3 years). One case with upper cervical spine tumor died from quadriplegia, respiratory and circulatory failure 10 days after operation. The short term results after operation were satisfactory in 44 cases. The local pain and neurological symptoms were improved or resolved. Megrim in 2 cases disappeared;1 cases with malignant nerve sheath tumors and 1 cases with chondrosarcoma died from metastasis, and systemic failure in 13 months, 24 months. Tumors focus recurred one year after the surgery in 1 case with osteoblastomas, 1 case with chondrosarcoma and 1 case with giant cell tumor. Conclusion The surgical approach and operative methods must be selected according to the location, surgical staging, characters of tumors; operative methods and postoperative comprehensive therapy play important roles on prognosis of the tumor cases.
2.Clinical applications of molecular biomarkers in urothelial carcinoma of bladder.
Liang CHENG ; Jia-wen XU ; Jia-jia HE ; Jing ZHAO ; Xiao-dong TENG
Chinese Journal of Pathology 2011;40(10):714-717
Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Basigin
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analysis
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Biomarkers, Tumor
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analysis
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genetics
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Carcinoma, Transitional Cell
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drug therapy
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genetics
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metabolism
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Gene Expression Profiling
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Humans
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In Situ Hybridization, Fluorescence
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Inhibitor of Apoptosis Proteins
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analysis
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Mutation
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Neoplasm Recurrence, Local
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metabolism
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Nuclear Proteins
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analysis
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Receptor, Fibroblast Growth Factor, Type 3
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analysis
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genetics
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Tumor Suppressor Protein p53
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analysis
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genetics
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Urinary Bladder Neoplasms
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drug therapy
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genetics
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metabolism
3.Application of Joint Computer Radiography System and High kV Radiography Technique in Diagnosis of Cardiac Disease
Lihua XIAO ; Jianjun HUANG ; Xing WEN ; Yunling JIA ; Shihong OU
Chinese Medical Equipment Journal 1989;0(02):-
Objective To investigate the application of computer radiography system in combination with high kV radiography technique to diagnose cardiac disease.Methods 30 patients with cardiac disease were taken chest photographs,which chest photographs by CR system and high kV radiography technique were compared with these by common high kV radiography.Results The good rate of air tube occupied is 98% in therapy group,but the rate is only 70% in common group.The discrepant comparison is significant differences.Conclusion It is more significant that CR system in combination with high kV radiography technique than common photograph to diagnose cardiac disease.
4.Recent advances in diagnosis of flat lesions of urinary bladder.
Liang CHENG ; Jia-wen XU ; Xiao-Dong TENG
Chinese Journal of Pathology 2010;39(9):577-581
Antigens, CD20
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metabolism
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Carcinoma in Situ
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classification
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diagnosis
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metabolism
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pathology
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Diagnosis, Differential
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Humans
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Hyaluronan Receptors
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metabolism
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Hyperplasia
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Precancerous Conditions
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diagnosis
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metabolism
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pathology
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Tumor Suppressor Protein p53
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metabolism
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Urinary Bladder
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metabolism
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pathology
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Urinary Bladder Neoplasms
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classification
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diagnosis
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metabolism
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pathology
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Urothelium
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metabolism
;
pathology
5.Recent advances in diagnosis of malignant soft tissue tumor of urinary bladder.
Liang CHENG ; Wen-bin HUANG ; Xiao-dong TENG ; Jia-wen XU ; Shao-bo ZHANG
Chinese Journal of Pathology 2010;39(2):126-130
Diagnosis, Differential
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Hemangiopericytoma
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metabolism
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pathology
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Hemangiosarcoma
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metabolism
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pathology
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Histiocytoma, Malignant Fibrous
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metabolism
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pathology
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Humans
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Immunohistochemistry
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Leiomyosarcoma
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metabolism
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pathology
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Nerve Sheath Neoplasms
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metabolism
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pathology
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Neuroectodermal Tumors, Primitive
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metabolism
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pathology
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Rhabdoid Tumor
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metabolism
;
pathology
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Rhabdomyosarcoma
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metabolism
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pathology
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Soft Tissue Neoplasms
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metabolism
;
pathology
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Urinary Bladder
;
metabolism
;
pathology
6.The X-ray features of breast ductal carcinoma in situ and its small invasive foci and correlation between mammographic features and prognostic biologic factors
Ya-Jia GU ; Qin XIAO ; Wen-Tao YANG ; Xiao-Jing ZHENG ; Rong-Feng GU ;
Chinese Journal of Radiology 1994;0(06):-
Objective To retrospectively evaluate the mammographic features of breast ductal carcinoma in situ (DCIS)and DCIS with small invasive foci,and to analyze the correlation between the mammographic findings and the prognostic biologic factors.Methods The mammographic examination was performed in 95 consecutive women with breast DCIS(n = 50)and DCIS with invasive foci(n = 45 ).The prognostic biologic factors including progesterone receptor(PR),C-erbB-2,and p53 were evaluated in 62 of 95 cases.Categorical data were expressed as percentages and analyzed by using the X~2 test,and furthermore the odds ratio was measured.Results(1)Only one abnormality was seen on mammography in 62 patients. Combined two abnormalities on mammography were seen in 26 patients.Mammograms were normal in 7 patients.(2)Calcifications with or without other abnormality were noted in 62 cases.Of them,73% (n =45)had higher probability of malignancy calcifications and the others were intermediate concern calcifications.Clustered calcifications(36 lesions)was the most common distribution,which usually accompanied by another abnormality.And then were segmental(18 lesions)distributed pattern.As far as the shape of mass (n = 22)was concerned,the oval shaped lesion(13 cases)was the most common,and the margin of the mass appeared as ill-defined in 15 eases,microlobulated in 1,circumscribed in 4,and obscured in 2,respectively.Isodensity mass had a higher frequency in this group(12/22,55%).Other non-calcification findings included architecture distortion(7 cases),local asymmetry (15 cases),global asymmetry (5 cases),and solitary dilated duct (3 cases),and most of them accompanied with other signs. (3)For expression profile of the biological factors,significant differences were found among malignant calcification group,intermediate concern calcification group,and non-calcification group. The odds of PR positive for the lesions noted as non-calcification were 11.00 times higher (X~2 =8.571 ,P=0.003 ;95% CI, 1.998—60.572)than the lesions noted as intermediate concern calcifications,and 8.80 times higher (X~2 = 9.748,P=0.002 ;95% CI,2.024—38.253)than the lesions noted as malignant calcifications.The odds of C-erbB-2 positive for the lesions showed as malignant calcifications were 12.35 times higher (X~2=7.353, P=0.007 ;95% CI,1.447—105.443)than the lesions showed as non-calcification,and 5.74 times higher (X~2=4.977,P = 0.026;95% CI,1.110—29.645)than the lesions showed as intermediate concern calcifications.Conclusion The mammographic features of DCIS and DCIS with small invasive foci were characteristic.Mammographic findings could be a prognostic markers,which could provide a possibility for making a treatment plan.
7.Diagnostic Value of Gap-Ligase Chain Reaction Enzyme Linked Immunosorbent Assay for Chlamydia Trachomatis Pneumonia in Neonatal and Small Infants
chun, DENG ; xiao-wen, LI ; jia-lin, YU ; shi-xiao, WU
Journal of Applied Clinical Pediatrics 1994;0(04):-
Objective To explore the diagnostic value of Gap-ligase chain reaction(LCR)-enzyme linked immunosorbent assay(ELISA)for Chlamydia trachomatis(CT) pneumonia in infants(28 days-3 months old baby was 16.9%(27/160 cases),and the incidence in 3-6 months old baby was 8.1%(12/149 cases).The clinical symptoms included that 25 cases(51.0%) had fever,48 cases(98.0%) with paroxysmal cough,45 cases(91.8%) with rhinocleisis,45 cases(91.8%) with spitting foam,49 cases(100%) with tachypnea,28 cases(57.1%) with lips cyanosis,26 cases(53.1%) with medium and moist rales,24 cases(49.0%) with dry rales,18 cases(36.7%) with phlegm whimper,29 cases(59.2%) with rough breath sounds in both lungs and there were 13 cases(26.5%) with conjunctivitis.Chest film and paper capacitor showed that bilateral extensive interstitial and(or) alveolar infiltration,over-inflation 23 cases(46.9%) had no lobal consolidation or pleural effusion.The WBC counts were normal or slightly high.All children were treated with cephalothin or penicillin before confirmation with CT infection.Eleven cases were treated with azithromycin after diagnosis with CT pneumonia and were cured 9 days after treatment and the others were not treated with azithromycin so their course prolonged from 15 to 44 days,among them there were 11 out-patients who were treated many times because of repeated cough.Conclusions CT is important pathogenic organism to cause pneumonia in neonatal and small infants.It is important to pay attention to the possibility of pneumonia caused by CT and make the diagnosis in early period as soon as possible and treat them with sensitive drug to shorten the course.
8.Research on spectral reflectance characteristics for Glycyrrhizae Radix.
Hui LI ; Cai-Xiang XIE ; Xiao-Jin LI ; Mei-Jia WEN ; Guang-Lin JIA ; Ming-Hui SHI ; Bao-Lin GUO ; Xiao-Guang JIA
China Journal of Chinese Materia Medica 2014;39(3):427-432
In order to study the spectral reflectance differences of Glycyrrhizae Radix under different growth conditions and lay the foundation for quantitative monitoring of Glycyrrhizae Radix remote sensing images, spectra of Glycyrrhiza species under different growth period and different varieties and different regions were measured by a portable spectrometer. The results showed that the reflectivity of annual G. uralensis was obviously higher than that of the two years plant in the visible light band own to the contents of crown layer chlorophyll. The reflectivity of two years G. pallidiflora was higher than that of G. uralensis in the near infrared band own to the leaf area index and the content of leaf water. The red edge spectrum of annual plant fluctuated largely than that of two years plant due to vegetation coverage and leaf area index. G. pallidiflora grew well than G. uralensis. Under different regions of the Glycyrrhiza species, spectral data analysis showed that within a certain range, the average annual precipitation and average annual evaporation were the major factors to affect the differences of Glycyrrhiza species spectral data under different regions owe to the leaf water content, the higher leaf water content, the lower spectral reflectance. The principal component analysis and continuum-removed method of the spectral data under different regions found that, within a certain range, the average annual precipitation and average annual evaporation were the major factors caused by the differences of Glycyrrhiza species spectral data under the different regions, Glycyrrhiza species spectral similarity related to the spatial distance.
Geography
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Glycyrrhiza
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chemistry
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Principal Component Analysis
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Spectrum Analysis
9.Application of the second metatarpophalangeal joint by traction prolong transplant repair the defects in the metacarpophalangeal joint
Jian-Wen LIAO ; Ze-Hua CHEN ; Jia-Chuan ZHUANG ; Jia-Jun ZHANG ; Zheng LI ; Shao-Xiao YU ; Zhen-Wei ZHANG ;
Chinese Journal of Microsurgery 2006;0(05):-
Objective Application of the second metatarpophalangeal joint by traction prolong trans- plant repair the defects in the metacarpophalangeal joint,reconstruct the function of it.Methods By means of the apparatus to prolong finger in advance,then transplant the second metatarpophalangeal joint to recon- struct metacarpophalangeal joint for seven cases of obsolete defects in the metacarpophalangeal joint.Results The average of finger prolong was 2.6 cm,consultation from 1 to 4 years.average 2.5 years,thai the trans- plant joints have all survived and osteal concrescence.Through the criterion Chinese Medical Association,good rate was 85.7%. Conclusion It' s a good method to repair obsolete defects in the metacarpophalangeal joint by transplant traction prolong of the second metatarpophalangeal joint.
10.A case report of sudden death caused by carcinoma of nasal sinuses with a huge liquid mass in cranial cavity.
Jia-xiong ZHANG ; Wen-tao ZOU ; Xiao-jing CAI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(11):948-948
Adult
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Brain Neoplasms
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complications
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Death, Sudden
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etiology
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Female
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Humans
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Nose Neoplasms
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complications