1.The change in epidural anesthesia between HRV and RAAS
Wen-Bin ZHANG ; Xian-Zhong SUO ;
Cancer Research and Clinic 2006;0(08):-
Objective To observe the change and relation between heart rate variability (HRV) and renin-angiotensin-aldostemne system (RAAS) under epidural anesthesia.Methods 16 cases patients ASAⅠ-Ⅱwere chose for epidural anesthesia.HRV,MAP and RT had been monitoring at pre-anesthesia (T1),15 min after inducing (T2),1 min after incising (T3),1 min pre-probing (T4),5 min after dragging uterus (T5), 1min after cutting uterus (T6) and the end point (T7).At same time,renin angiotensin and aldostemne were measured by drawing radial arterial blood when it was T1,T2,T3,T5,T7.Results Comparing with T1,LF/ HF increased significantly (P
2.Expression of homeobox gene MSX-2 during cranial suture fusion of SD rats
Xian-xian, YANG ; Zhao-wen, YAN ; Mei, ZHANG ; Ru-hong, ZHANG ; Xiong-zheng, MU
Journal of Shanghai Jiaotong University(Medical Science) 2009;29(6):693-697
Objective To investigate the expression of homeobox gene MSX-2 during cranial suture fusion of SD rats and discuss its significance. Methods SD rats aged 1, 2, 5, 8, 12, 15, 18, 22, 30 and 45 days were selected, and immunohistochemistry and Real-time PCR were employed to localize and quantify the expression of MSX-2 in different regions of cranial sutures. Results MSX-2 expressed in calvarial suture tissues including the extreme ends of the osteogenic fronts and the underlying dura mater. The expression of MSX-2 was low in posterior frontal suture (PF) and sagittal suture (SAG) from postnatal day 1 to day 8 before the initiation of suture fusion, while it was higher in PF than in SAG from postnatal day 12 to day 22 after the initiation of PF suture fusion. The expression of MSX-2 significantly declined in PF and was moderately higher than that in SAG from postnatal day 30 to day 45 after the initiation of suture fusion. Conclusion There is different expression of MSX-2 in PF and SAG during different suture fusion periods, which suggests the expression of MSX-2 may participate in the regulation of cranial bone development and the fusion of cranial sutures.
3.Congenital aortic arch twist abnormality with thoracic aorta aneurysm: a case report.
Wei-hua ZHU ; Wen-bin ZHANG ; Xian-mei HUANG
Chinese Journal of Pediatrics 2005;43(7):540-540
Abnormalities, Multiple
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diagnosis
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diagnostic imaging
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Aorta, Thoracic
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abnormalities
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diagnostic imaging
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Aortic Aneurysm, Thoracic
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congenital
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diagnosis
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diagnostic imaging
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Aortic Diseases
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congenital
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diagnosis
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diagnostic imaging
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Child
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Diagnosis, Differential
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Humans
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Male
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Radiography
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Rare Diseases
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X-Rays
4.Primary exploration of the product quality supervision on medical devices in use.
Xintao ZHANG ; Qing HAO ; Xian SHI ; Jiong ZHU ; Wen LI
Chinese Journal of Medical Instrumentation 2014;38(3):207-209
This paper focuses on issues needed to be clear towards the product quality supervision of medical devices in use. The life circle of medical devices, the supervision regarding its boundary, target, emphasis, basis and standards have been analyzed in turn. A clear and creative idea is also provided for theoretical exploration of the supervision on medical devices in use.
Materials Management, Hospital
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Quality Assurance, Health Care
5.Blood screening and gene detection of thalassemia in the pregnant couples in Changshou district
Lingyan ZUO ; Zezhen HE ; Xian CHE ; Min ZHANG ; Hao WEN
Chongqing Medicine 2015;(31):4370-4372
Objective To establish blood screening and genetic detection of thalassemia trait in pregnant couples in Chang‐shou area so as to provide guidance for aristogenesis and prenatal diagnosis .Methods A total of 1 760 pregnancy in maternal and child health hospital treated from January 2013 to October 2014 were selected for study .The component of hemoglobin was ana‐lyzed as primary screening and genotype of pregnant couples were ensured in which primary screening result is positive .Results There were 27 cases suspected as α‐thalassemia (positive rate was 1 .53% ) and 25 cases suspected as β‐thalassemia(positive rate was 1 .42% ) in the primary screening(n=1 760) .The positive rate of gene carrier were 31 .51% (n=438) in women and 33 .33%(n=27) in men .Conclusion The routine screening of thalassemia could guide aristogenesis in high incidence area and provide terms of prenatal diagnosis and genetic counseling .
6.The investigation of methods for prevention of anastomotic stenosis after resection of esophageal cancer
Renzhu WEN ; Mingwu CHEN ; Lei XIAN ; Lei DAI ; Yanan ZHANG
China Oncology 2016;26(6):552-555
Background and purpose:Esophageal cancer is one of the common malignant tumors in our country. Anastomotic stenosis is a common complication after resection of esophageal cancer, seriously affecting the quality of life of patients after operation. By changing anastomosis, this study explored the methods for prevention of anastomotic stenosis after esophageal cancer surgery.Methods:Patients were randomly divided into groups. Patients admitted on odd dates were placed in the control group whereas patients admitted on even dates were placed in the experimental group. Patients in the control group were treated with gastroesophageal anastomosis using anastomat for gastroesophageal anastomosis. Anastomotic stomach was contracted by purse string suture at first, and then treated with stapler gastroesophageal anastomosis, before the gastroesophageal anastomosis was carried out on patients in the experimental group. After 6 months’ follow-up, the incidences of anastomotic stenosis between the two groups were compared.Results:The postoperative anastomotic stenosis rate in the control group was 19.2%, while that in the exper-imental group was 0%. There were statistically signiifcant differences between them (χ2=22.8,P<0.005). The incidence of anastomotic stenosis in the control group was signiifcantly higher than that in the experimental group.Conclusion:Anastomotic stomach contracted by purse string suture before stapler gastroesophageal anastomosis can effectively reduce the occurrence of anastomotic stenosis after esophageal cancer surgery.
7.Exercise based on traditional Chinese medicine for patients with stable chronic obstructive pulmonary disease
Wen ZHANG ; Xian-Qiao JIN ; Wen-Hua CHEN ; Wei-Qing WU ; Rong YANG ; Yan-Yan YU ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(12):-
Objective To make up an exercise prescription based on traditional Chinese medical training (EP-TCMT) for patients with stable chronic obstructive pulmonary disease (COPD).Methods Eighty-five pa- tients with stable COPD were randomly divided into a control group (CG group),a traditional Chinese medicine group ( TC group) and an exercise prescription group ( EP group).The patients in the TC and EP groups were giv- en intensive training for 8 weeks.Their 6 rain walk distance (6MWD) and Borg scale scores were assessed before and after the treatment.Results The 6MWD in the TC group increased from 337.68?59.18 m to 386.14?76.71 m,while those in the EP group improved from 348.00?55.94 m to 425.17?53.22 m.The Borg scale scores in the TC group decreased from 3.14?1.94 to 2.32?1.25,while those in the EP group declined from 3.45?1.84 to 1.72?0.70.Conclusion Making up EP-TCMTs is feasible.Additional treatment was found to improve exercise tolerance and decrease dyspnea in COPD patients.Exercise therapy based on traditional Chinese methods is easy and safe.
8.Significance of Renal Evaluation of Vasopressin-Deficient Brattleboro and Wistar Rats by Using Different Concentrated Gadolinium Diethylenetetramine Pentaacetic Acid Dynamic Enhanced Magnetic Resonance Imaging
jian-jun, WEN ; li, YANG ; jian-guo, WEN ; hong, ZHANG ; gui-xian, WANG ; bao-chi, LIU
Journal of Applied Clinical Pediatrics 1992;0(05):-
ObjectiveTo explore the renal functions of vasopressin-deficient Brattleboro(BB) rats by using different concentrated Gadolinium-diethylenetetramine pentaacetic acid(Gd-DTPA) dynamic enhanced magnetic resonance imaging(MRI).MethodsThe study included 14 BB rats(male rats of 3 month-old) and 14 normal male Wistar rats used as control group.Dynamic MRI was performed by using either a low dosage(0.05 mmol/kg) or a high dosage of Gd-DTPA(0.5 mmol/kg).Data of 0-60 min renal cortex,medulla and pelvic were obtained after using contrast medium.MRI of kidneys at different time was analyzed and the mean relative signal intensity(RSI) was measured.Then the RSI curves of different groups were marked.Data of each group were caculated separately by SPSS 11.0 software.ResultsThe findings demonstrated that RSI curves of the vasopressin-deficient kidneys showed different patterns as compared with those of the control group(P
9.Effects of early enteral nutrition on prognosis of patients with sustained esophageal caner
Bo ZHANG ; Wen ZHANG ; Xuequan LUO ; Shengting QIANG ; Zhiyi ZHAO ; Huazeng CHEN ; Guoming XIAN ; Feng ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(8):1313-1314
Objective To investigate the effect of early enteral nutrition.Methods 248 patients with esophageal and gastric carcinoma were randomly divided into two groups,and received enteral nutrition(EN)and parenteral nutrition(PN)each continuously for 6 days after operation.The body weight,blood routine test,liver function,and postoperative day 8 were compared with those before operation.Results The body weight,red blood cell count,and the levels of hemoglobin,serum albumin and transaminase decreased less in EN group than those in PN group(P<0.01).The complication rates of anastomotic fistula,pulmonary infection,and delayedincision healing and average volume of pleural effusion were 0,13.8%,0,780ml in EN groups,while 3.2%,28.2%,7.2%,1842ml in PN group.Conclusion Early postoperative enteral nutirtion after esophageal carcinoma surgery can improve nutritional status and reduce complications in comparision with parenteral nutrition.
10.Enhanced effect of guizhi plus Gegen Decoction on learning and memory disorder in LPS induced neuroinflammatory mice.
Ying XU ; Zong-Qi ZHANG ; Yan ZHAO ; Xian-Wen DONG ; Xing-Yu WANG ; Li-Qing ZHANG
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(2):179-184
OBJECTIVETo explore the potential effect of Guizhi plus Gegen Decoction (GGD) in improving learning and memory of lipopolysaccharides (LPS) induced neuroinflammatory mice and its possible mechanisms.
METHODSTotally 63 male ICR mice were randomly divided into 5 groups, i.e., the normal control (n = 13), the model group (n = 13), the low dose GGD group (n = 10), the high dose GGD group (n = 14), and the positive control group (n = 13). Mice were intraperitoneally injected with LPS (0.33 mg/kg) to induce Alzheimer's disease (AD) model. Mice in the high and the low dose GGD groups were administered with 12 g/kg or 6 g/kg by gastrogavage for 4 successive weeks. Mice in the control group were intraperitoneally injected with minocycline (50 mg/kg) for 3 days. By the end of treatment LPS were injected 4 h before behavior test each day, and then behavior test was conducted in mice of each group. Effect of GGD on learning and memory of AD mice was observed by using open field test, novel object recognition task, and Morris water maze.
RESULTSOpen field test showed there was no statistical difference in the movement time and the movement distance among all groups (P > 0.05), suggesting that LPS and GGD had no effect on locomotor activities of mice. In novel object recognition test, AD mice spent significantly shorter time to explore novel object after they were induced by LPS (P < 0.05), while for AD mice in the low and high dose GGD groups, their capacities for exploration and memory were significantly improved (P < 0. 05, P < 0.01). Results of Morris water maze showed that AD mice exhibited increased escape latency (P < 0.05) and spent much less time in swimming across the original platform (both P < 0.05). However, AD mice in the low and high dose GGD groups had obvious shortened latency and increased time percentage for swimming (P < 0.05, P < 0.01).
CONCLUSIONGGD possessed certain improvement in learning and memory disorder of LPS induced AD mice.
Alzheimer Disease ; chemically induced ; drug therapy ; psychology ; Animals ; Drugs, Chinese Herbal ; therapeutic use ; Lipopolysaccharides ; adverse effects ; Male ; Memory Disorders ; prevention & control ; Mice ; Mice, Inbred ICR ; Neuritis ; chemically induced ; drug therapy ; psychology ; Phytotherapy