1.Analysis on the elements of teaching ability in the field of traumatology and orthopedics of TCM
Changqing ZHAO ; Yueguang FAN ; Feng HUANG ; Wen SHU
Chinese Journal of Medical Education Research 2015;14(4):391-393
Teaching ability is the comprehensive embodiment of expertise and personal cultivation,and it is closely related to teaching results.The teaching ability of teachers in the field of traumatology and orthopedics of TCM is developed in their practice of clinical work and teaching practice,which reflects the efficiency and quality of their classroom teaching and clinical teaching.The elements of teaching ability in the field of traumatology and orthopedics of TCM should be strengthened by approaches such as professionalism,the ability of teaching design,the expertise of modem educational technology and professional dedication.
3.Gemcitabine combined with cisplatin and methylprednisolone sodium succinate in chemotherapy for relapsed or refractory T cell non-Hodgkin lymphoma.
Shu ZHAO ; Qing-yuan ZHANG ; Wen-zhou SUN
Chinese Journal of Oncology 2010;32(4):316-316
Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Cisplatin
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administration & dosage
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Deoxycytidine
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administration & dosage
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analogs & derivatives
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Female
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Humans
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Lymphoma, T-Cell
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drug therapy
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pathology
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Male
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Methylprednisolone Hemisuccinate
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administration & dosage
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Middle Aged
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Neoplasm Recurrence, Local
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drug therapy
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Remission Induction
4.Prevalence and molecular proifle of theStaphylococcus aureus strains harboring tstand/or pvl genes
Huanqiang ZHAO ; Yuhan ZOU ; Shu JIN ; Wen SHU ; Rong TANG ; Qingzhong LIU
Chinese Journal of Infection and Chemotherapy 2016;16(3):353-358
Objective To investigate the prevalence, accessory gene regulator (agr) and staphylococcal cassette chromosome mec (SCCmec, only for methicillin resistantS. aureus, MRSA) types of theS. aureus strains carrying toxic shock syndrome toxin-1 (tst) and/or panton-valentine leukocidin (pvl) genes.Methods Nine hundred and sixteen isolates ofS. aureus were collected from seven hospitals in Shanghai and Zhejiang Province and subjected to detection oftst,pvl,mecA andmecC genes by polymerase chain reaction (PCR). Theagr and SCCmec (only for MRSA) types were determined in thetst orpvl gene positive isolates.Results Of the 916 isolates, 208 carriedtst gene (22.7%), 35 harboredpvl gene (3.8%), and 665 weremecA positive (MRSA). No isolate was mecC positive. Out of the 665 MRSA isolates, 198 hosted thetst gene (29.8%). The most commonagr and SCCmec types were agr 2 (97.0%) and SCCmec II (94.4%), respectively. For thepvl gene, only 14 isolates were positive (2.1%). Theagr 1 (85.7%), SCCmecIII (42.9%) and SCCmec IVa (28.6%) were the most commonagr type and SCCmec type. In the 251 methicillin-sensitiveS. aureus (MSSA) isolates, 10 carriedtst gene (4.0%) and 21 carriedpvl gene (8.4%). The prevalence oftst gene in MRSA was higher than that in MSSA, while the prevalence ofpvlgene was just the opposite. However, the prevalence ofpvlgene in MRSA isolates from Zhejiang Province was higher than that in the MRSA isolates from Shanghai (P<0.05).Conclusions The prevalence oftst gene in MRSA is signiifcantly higher than that in MSSA. The prevalence ofpvlgene is low in theS. aureus isolates studied. However, clinicians should pay close attention to these strains due to the implication of PVL toxin in some
severeS. aureus infections.
5.Alterations of protein phosphatase-2A in peripheral lymphocytes in mild cognition impairment and Alzheimer's disease
Zhong-Sen QU ; Yong-Bo ZHAO ; Xing-Bin WANG ; Wen-Wen LIU ; Qiao-Shu WANG ;
Chinese Journal of Neurology 2005;0(10):-
Objective To explore the alterations of protein phosphatase-2A (PP-2A) in lymphocytes in mild cognition impairment (MCI) and Alzheimer's disease (AD).Methods The activity PP-2A of was measured by ~(32)p liquid seintillography for incorporated radioactivity in control group(n=11) , the MCI group(n=11),and the AD group(n=11).The expression of PP-2A was determined by Western blot.Results In the control group,the activity of PP-2A (1.01?0.09) and the expression of PP-2A (0.96?0.07) were high while in the MCI group,the activity of PP-2A (0.71?0.12) and the expression of PP-2A (0.80?0.05) were decreased (both P
6.DCX and GFAP time-course expression in dentate gyrus of hippocampus following kainic acid-induced seizures on C57/BL6 mice.
Pei-Fei GU ; Hua WEN ; Wen-Shu HUANG ; Song-Yan ZHAO ; Yu SHANG
Chinese Journal of Applied Physiology 2011;27(1):11-12
Animals
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Dentate Gyrus
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metabolism
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Epilepsy
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chemically induced
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metabolism
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Glial Fibrillary Acidic Protein
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metabolism
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Hippocampus
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metabolism
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Kainic Acid
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Male
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Mice
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Mice, Inbred C57BL
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Microtubule-Associated Proteins
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metabolism
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Neurons
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metabolism
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Neuropeptides
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metabolism
7.Study on clinical characteristics and therapeutic outcomes of 173 patients with Takayasu arteritis
Shu-yun WEN ; Wen ZHANG ; Yan ZHAO ; Xiao-feng ZENG ; Feng-chun ZHANG
Chinese Journal of Rheumatology 2011;15(9):604-607
ObjectiveTo study the clinical features, arterial involvement, therapeutic strategies and outcomes of Takayasu arteritis (TA). MethodsThe clinical symptoms, arterial images, inflammatory parameters and follow-up information of 173 patients with TA were retrospectively studied. Comparisons between groups were performed by t-test. ResultsThere were 136 female and 37 male patients in this study. The mean age at onset was(26±11 ) years. Hypertension, pulse deficit or asymmetrical pulse, and fever were present in 46.6%, 41.1%, 28.7% of patients, respectively. The distribution of arterial involvement were 64.7%in aorta, 9.8% in pulmonary artery, 19.1% in innominate artery, 65.9% in common carotid arteries, 65.3%in the subclavian artery, 36.2% in the renal artery, 12.1% in the vertebral artery, and 5.8% in coeliac axis.Elevated erythrocyte sedimentation rate(ESR) was found in 61.0% patients. Active tuberculosis or history of tuberculosis was implicated in 45 patients(26.0%). Ten patients(5.8%) were hepatitis B virus carriers.Among 105 followed-up patients, 98 patients(94.2%) achieved persistent remission, 17 patients relapsed when corticosteroids were tapered. ConclusionCorticosteroids combined with or steroid alone, supplemented with endovascular intervention procedures or surgical bypass procedures when necessary, can effectively control the clinical symptoms and inflammatory parameters and improve the quality of life of patients.
8.The analysis of factors affecting the quality of life of family caregivers of patients with Alzheimer′s disease
Pingjing JANG ; Xiaolin TAN ; Jie HUANG ; Ke ZHAO ; Yan WEN ; Fei CHEN ; Zhenhong JIANG ; Shu HU
Chongqing Medicine 2015;(30):4201-4203,4206
Objective To investigate the quality of life and its influencing factors of families primary caregivers of dementia patients .Methods The typically self made questionnaire ,WHO quality of life measurement profile (WHOQOL‐BREF) ,zarit bur‐den of care scale(ZBI) ,social support rating scale (SSRS) et al were adopted to investigate 64 caregivers of AD patients .Results (1) The overall quality of life of family caregivers of total subjective feelings were significantly lower than the general health status of subjective feeling score (t= -2 .217 ,P=0 .030) .The field of physiological and psychology points have no statistically significant difference in comparison with Chinese norm (t= -0 .252 ,-1 .994 ,P=0 .801 ,0 .050);the field of social and environment points have statistically significant difference compared with norm(t= -3 .830 ,3 .658 ,P=0 .000 ,0 .001) .(2) caregiver who have spouse , poor parent child relationship and patients with somatic diseases and mental behavior symptoms have lower quality of life(P<0 .05) .(3)Total score of Quality of life was negatively associated with total score of care burden (r= -0 .433 ,P=0 .000) ,while was significant positive associated with total score of the social support (r=0 .346 ,P=0 .005) .(4)Marital status ,parent‐child rela‐tionship ,physical illness and social support were the main factors affecting the quality of life(r2 =0 .409) .Conclusion Strengthen the social support and psychological intervention of dementia caregivers who has a spouse ,poor parent-child relationship and poor physical condition may help to improve the quality of life .
9.Analysis of Newborn′s Weight Investigation in Some Areas of Henan Province
xiao-shu, LI ; hu, ZHAO ; wen-juan, YIN ; ai-hong, WU ; su-fang, SHEN
Journal of Applied Clinical Pediatrics 2004;0(09):-
Objective To investigate the full-term newborn′s weight in Zhengzhou city and nearby areas around Zhengzhou in Henan province.Methods Each group newborn′s weight was divided with sex and city.We studied the regularity of full-term newborn′s weight,and examined the cause of the newborn′s weight rising.Results The average newborn′s weight in Zhengzhou was (3449.06?453.97) g,which in nearby areas around Zhengzhou was (3352.07?429.91) g.The average newborn′s weight in Zhengzhou was 86.97 g higher than other cities (P