1.Application of Spiral CT for Pancreatic Adenocarcinoma: Emphasis on the Value of the Tumor-pancreas Contrast
Chinese Journal of Medical Imaging Technology 2001;17(2):108-110
Objective To evaluation the application value of two-phase enhanced spiral CT in pancreatic adenocarcinoma. Methods Two-phase enhanced spiral CT was performed in 27 cases of pancreatic adenocarcinoma. After plain CT examination, performed arterial phase(25s after infusion)and portal venous phase(60~70s after infusion)with a 150ml bolus injection of contrast material at 3ml/s. CT attenuation values of tumor and normal pancreas in all scanning phase were obtained and the tumor-pancreas contrast was calculated. Results Mean tumor enhancement were 48±8 HU(arterial phase)and 72±6 HU(portal venous phase), normal pancreas enhancement were 125±18 HU、98±11 HU, mean tumor-pancreas contrast was significantly differenced on arterial phase (73±21 HU)and portal venous phase (25±12 HU). Conclusion Excellent tumor-pancreas contrast is obtained with arterial phase scans, as such it is of significance reference value for diagnosis pancreatic adenocarcinoma.
2.Clinical Observation on 60 Cases of Functional Dyspepsia with Stagnation of Qi due to Spleen Deficiency Treated by Jianpi Xiaozhang Granule
Wen LIU ; Ming CHEN ; Jinmei DENG ;
Journal of Traditional Chinese Medicine 1993;0(05):-
0.05),and no adverse reaction was found in both groups.Conclusion:Jianpi Xiaozhang Granule and motilium have obvious and similar therapeutic effect on functional dyspepsia with stagnation of Qi due to spleen deficiency.
4.Feasibility of galactomannan assay in bronchoalveolar lavage fluid in diagnosis of hematologic malignancy patients with invasive fungal infections.
Yun LENG ; Wen-Ming CHEN ; Jin-Wei LIU
Chinese Journal of Hematology 2011;32(8):551-552
Adolescent
;
Adult
;
Aged
;
Bronchoalveolar Lavage Fluid
;
Feasibility Studies
;
Female
;
Hematologic Neoplasms
;
microbiology
;
Humans
;
Lung Diseases, Fungal
;
diagnosis
;
etiology
;
Male
;
Mannans
;
analysis
;
Middle Aged
;
Young Adult
6.Evaluation of left ventricle systolic function and postsystolic shortening in essential hypertension with different patterns of ventricular geometric models by strain and strain rate imaging
Chao LIU ; Ming CHEN ; Xiang ZHANG ; Wen LI
Chinese Journal of Ultrasonography 2008;17(10):843-846
Objective To investigate regional systolic function in left ventricle(LV) and postsystolic shortening(PSS) in patients with essential hypertension with different remodeling patterns of LV by strain and strain rate imaging. Methods According to the level of LV mass index and relative wall thickness, forty patients with hypertension were divided into LV normal geometry(LVN) group and LV remodeling(LVR) group, with thirty healthy subjects as control. The strain and strain rate were compared among the basal,middle and apex segments. Results Compared with control, systolic peak strain and strain rate in both groups of LVN and LVR were decreased significantly(P<0.05). Prevalence of PSS in LVR group (55%) was higher than that in LVN group(39%) and control(22%) with significant differences(P<0.01).Conclusions High prevalence of pathologic PSS in patients with hypertension could implied that unbalance of segmental motion in regional myocardial ischemia. However,presence of PSS in healthy subjects might be the result of synchronization and balance of normal myocardium under physical condition.
7.Related factors of death in patients with gas burst induced burn.
Lin-hong LIU ; Wen-jie REN ; Ming-jun WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(10):611-613
Adult
;
Burns
;
etiology
;
mortality
;
China
;
epidemiology
;
Coal Mining
;
Explosions
;
Female
;
Gases
;
Humans
;
Male
;
Middle Aged
;
Retrospective Studies
;
Young Adult
8.Effects of uremia patients sera on bone marrow derived CFU-E proliferation
Jin-Wei LIU ; Qian-Mei SUN ; Wen-Ming CHEN ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To investigate the existence of the erythropoiesis inhibitors(?).Methods Twelve patients suffered from uremia with anemia were studied[5 males,and 7 females,(50?12)years].Methylcellulose culture technique was used to culture mice bone marrow cells.The sera from the uremia patients were added to CFU- E and BFU-E culture medium with final concentrations of 1,25%,2.5% and 5%,Mice bone marrow cells were ob- tained from the female Balb/c mice.In vitro CFU-E and BFU-E culture in the presence of sera from uremia patients was compared with that in the presence of normal human subjects with the use of normal mice bone marrows.Re- suits The effects of the sera from uremia patients on CFU-E and BFU-E colon growth were in a dose-dependent manner.The effect was correlated with the concentrations of the sera(P
9.Clinical analysis of 221 cases of inhalation injury induced by gas explosion.
Lin-hong LIU ; Wen-jie REN ; Ming-jun WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(8):494-495
Adolescent
;
Adult
;
Burns, Inhalation
;
etiology
;
therapy
;
Explosions
;
Female
;
Gases
;
Humans
;
Male
;
Retrospective Studies
;
Young Adult
10.Necroptosis Involves in Mechanism of Lung Injury Induced by Intestinal Ischemia-Reperfusion
Peng YANG ; Ming WEI ; Xiang LI ; Shihong WEN ; Kexuan LIU
Journal of Sun Yat-sen University(Medical Sciences) 2017;38(3):321-326
[Objective] To explore whether necroptosis is involved in the mechanism of lung injury induced by intestinal ischemia-reperfusion.[Method] Thirty-two healthy male Sprague-Dawley rats were randomly assigned into 4 groups (n--8):sham operation group (sham group),isehemia/ reperfusion group (I/R group),necroptosis inhibitor necrostatin-1 group (Nec-1 group) and solvent dimethyl sulfoxide (DMSO) group (DMSO group).Model of intestinal I/R injury was produced by clamping the superior mesenteric artery for 1.5 h followed by 6 h reperfusion in rats.Necrostatin-1 1.0 mg/kg was administered 30 min before occlusion in Nec1 group,while the equal volume of DMSO was given instead in DMSO group.The rats were sacrificed at 6 h of reperfusion and the lung tissues were removed for measurement of wet-dry ratio and microscopic examination and scored.The expression of receptor-interacting protein 1 (RIP1) and receptor-interacting protein 3 (RIP3) in lung tissues was detected using Western-blot and immunohistochemistry.[Result] Compared with sham group,lung morphology score and wet/dry ratio in I/R,DMSO group raised (P < 0.05).Lung morphology score and wet/dry ratio statistically declined in Nec-1 group compared with I/R and DMSO group (P < 0.05),while there was no statistical difference of wet/dry ratio between sham group and Nec-1 group (P > 0.05).As the result of westernblot and immunohistochemistry showed,the expression of RIP1 and RIP3 was up-regulated in I/R group and DMSO group (P <0.05),which was inhibited by Nec-1 in Nec-1 group (P < 0.05).[Conclusion] Necroptosis is involved in the mechanism of lung injury induced by intestinal ischemia-reperfusion,and Nec-1,the special inhibitor of RIP1,can reduce the injury.