1.Investigation and analysis on teaching evaluation of professional teachers in military medical university
Juan LU ; Shihao WEN ; Weimin REN
Chinese Journal of Medical Education Research 2005;0(05):-
The course arrangement,teaching contents and means and other items were investigated and analyzed in this research of teaching evaluation of professional teachers in military medical university.The results showed that the levels of post-oriented education teaching were increasing in updating ideas and accumulating experiences in recent years.However,there still existed a few problems such as too much basal theories,lack of real army circs in the contents and little practice in the manners.Therefore,the quality of post-oriented education in military medical university is expected to be developed to a higher level.
2.Recent advances in pericytes angiogenic signaling pathways.
Wen-bao LU ; Xiao-rui SHI ; Rui-juan XIU
Chinese Journal of Pathology 2011;40(6):423-426
Angiopoietins
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metabolism
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physiology
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Animals
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Cell Proliferation
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Endothelial Cells
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cytology
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physiology
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Humans
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Neoplasms
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blood supply
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Neovascularization, Pathologic
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physiopathology
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Neovascularization, Physiologic
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physiology
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Pericytes
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cytology
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metabolism
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physiology
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Proto-Oncogene Proteins c-sis
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metabolism
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physiology
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Receptor, Platelet-Derived Growth Factor beta
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metabolism
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physiology
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Receptor, TIE-2
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metabolism
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physiology
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Signal Transduction
4.CD_4~+ CD_(28)~(null) T cell numbers of peripheral blood in patients with coronary heart diseases
Li-Juan HUANG ; Ying CUI ; Wen-Ying SUN ; Gui-Qin DU ; Lu-Lu LI ;
Chinese Journal of Laboratory Medicine 2001;0(04):-
Objective To investigate changes in CD_4~+ CD_(28)~(null)T cell numbers of peripheral blood and the expression of perforin in patients with coronary heart disease.Methods Sixty-eight patients with acute coronary syndromes,56 with stable angina and 65 healthy subjects were enrolled in the study.CD_4~+ CD_(28)~(null)T lymphocytes were measured by flow cytometric analysis.Results The numbers of CD_4~+ CD_(28)~(null)T lymphocytes in patients with acute coronary syndromes were higher than those in patients with stable angina and in the control subjects(11.6 % vs 2.84% and 0.59%,P
5.Effects of water extraction of Salvia miltiorrhiza in sperm quality of mice
Huanqun ZHOU ; Wen ZHOU ; Shan LU ; Yan XIE ; Aiai WANG ; Juan LIU ; Huifang LIU
The Journal of Practical Medicine 2016;32(20):3342-3345
Objective To research effects of water extraction of Salvia miltiorrhiza in sperm quality of mice. Methods Forty adult male Kunming mice were randomly divided into 5 groups, including low concentration group, medium concentration group, high concentration group, control group and positive control group in eight mice in each group. The low, medium and high concentration groups were given by gavage with 1 500, 3 000 and 6 000 mg/kg water extraction of salvia miltiorrhiza once a day respectively, while the control group was given gavage with 10 mL/kg normal saline daily, as well as the positive control group was injected with 100 mg/kg cyclophosphamide once; All mice were sacrificed after 30 days. We measured the weight gain, viscera coefficient and sperm quality in each mouse. Results There were no statistical difference in the weight of every week, increase of the weight, testis and epididymis coefficients among the control group, the low, medium and high concentration groups (P > 0.05), while the weight and weight increase were significantly higher than that in the positive control group (P < 0.05). Sperm concentration, viability, morphology, motility, PR, VSL, VAP of low, medium and high concentrations group were significantly improved than the control group (P < 0.05), and the sperm quality in the four groups were higher than that in the positive control group (P < 0.05). Conclusion Water extraction of salvia miltiorrhiza can obviously improve the sperm viability, morphology, and motility of mice.
6.Pharmaceutical Care for One Case of Renal Transplantation Recipient with Pulmonary Infection
Guiping GUO ; Yao LU ; Xiangduan LIU ; Xiaoliang QIAN ; Juan BAI ; Aidong WEN ; Yin WU
China Pharmacist 2015;(11):1928-1930
Objective:To provide some thoughts for pharmaceutical treatment and care for the patients with pulmonary infection af-ter renal transplantation. Methods:Clinical pharmacists participated the whole treatment process of one case of pulmonary infection af-ter renal transplantation. According to the literatures combined with medical history, clinical symptoms and lab results, the drug treat-ment process of the patient was analyzed, and the key points of the optimized pharmaceutical care were summarized. Results: The pharmaceutical care included the dose adjustment of immunosuppressants at the early phase of the disease and after the improvement of clinical symptoms, attention paid to the interactions between multiple anti-infective drugs and immunosuppressive agents, dosage ad-justment based on the renal function of the patient, monitoring adverse drug reactions and drawing up personalized regimen. Conclu-sion:Through comprehensive medication monitoring, clinical pharmacists can help physicians develop timely and effective treatment programs and provide professional and effective pharmaceutical care for patients.
8.A comparison of four methods for extraction of human fecal DNA by using real time PCR
Zhong-Wen WU ; Ying HAN ; Hai-Feng LU ; Lan-Juan LI ; Ji-Fang SHENG ; Jian ZUO ;
Chinese Journal of Laboratory Medicine 2001;0(01):-
Objective To compare the relative efficacy and quality of extraction of human fecal DNA using four methods.Methods Real-time PCR were utilized for analysis both quantification and quality of the fecal targeted bacteria(including gut all eubaeterium,Bacteriodes-PrevoteUa group,Bifidobacterium spp Enterobacteriaceae and Enterococcus spp)by using 16s rRNA gene-targeted genus or group-specific primer sets.Results The negative rat of PCR product from method 3(phenol-chloroform plus bead-beating) was about 40%(4/10)by using universal primers,the PCR inhibition disappeared after fecal DNA purified with column.The total fecal 16s rRNA gene copy numbers(per gram of wet weight of feces)as well as the numbers of Bacteriodes-Prevotella group from method 1(QIAamp~DNA stool mini kit)and 4(QIAamp~ DNA stool mini kit combined with bead-beating)was higher significantly than that from method 2(FastDNA ~Kit,Biol01)and 3(P
9.Predictive Effect of Mean Platelet Volume in Patients with Portal Vein Thrombosis: A Meta-analysis of Case-control Studies
Wen-Yi LIN ; Xuan LU ; Feng-Juan FAN ; Yu HU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2018;38(4):575-581
Mean platelet volume (MPV) is an early marker of platelet activation.Larger platelets,compared to small ones,increase platelet adhesion and aggregation,and present a higher thrombotic activity.Some studies have explored the association between MPV and the morbidity of portal vein thrombosis (PVT).The aim of this study was to evaluate the predictive effect of MPV in patients with PVT by a meta-analysis.We searched Pubmed,Web of Science,SCOPUS,OVID,CNKI and CBMD from database inception to September 13,2017.Seven studies in accordance with selection criteria were included.The extraction of basic data was independently conducted by two reviewers.The mean difference in MPV between PVT patients and controls were pooled with weighted mean difference (WMD)and 95% confidence interval of 0.88 fl (95% CI:0.61-1.15).A random-effect model was chosen for an obvious heterogeneity in the pooling (Chi-square=27.12,df=6,P<0.0001,I2=77.9%).The sources of heterogeneity were from the difference of primary disease of participants and portal vein diameter.Taken together,our results reveal that MPV is a predictive indicator in patients with PVT.
10.The predictive value of serum estradiol level during early phase of controlled ovarian hyperstimulation in IVF-ET
Juan LIU ; Huanqun ZHOU ; Wen ZHOU ; Shan LU ; Yunping NI ; Dongying TANG ; Yijiao CHEN
The Journal of Practical Medicine 2016;32(13):2157-2160
Objective To evaluate the value of serum E2 levels during COH in predicting IVF-ET outcome. Method Data from 311 IVF-ET cycles received long protocol were collected and analyzed according to E 2 levels 5 days after stimulation:Group A (E2≤500 pmol/L), Group B (500