With the in-depth study of oral hypoglycemic drugs , the safe-ty and effectiveness of glyburide in the treatment of gestational diabetes has been confirmed.Related studies showed that glyburide had a lower placental transmission.And the studies about placental transport mecha-nisms showed that it might be associated with a variety of transport pro-teins, including ATP ( adenosine 5 ’ -triphosphate ) -binding cassette ( ABC ) transporters and organic anion transporting polypeptides ( OATPs).
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