1.Well-differentiated papillary mesothelioma: report of a case.
Chinese Journal of Pathology 2007;36(6):431-432
Adult
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Biomarkers, Tumor
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metabolism
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Calbindin 2
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Female
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Follow-Up Studies
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Humans
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Mesothelioma
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metabolism
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pathology
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surgery
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Mucin-1
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metabolism
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Peritoneal Neoplasms
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metabolism
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pathology
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surgery
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S100 Calcium Binding Protein G
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metabolism
4.Expression of Endothelin in Kidneys of Rats with Unilateral Ureteral Obstruction
guo-lan, XING ; zhang-suo, LIU ; jian-guo, WEN
Journal of Applied Clinical Pediatrics 2004;0(09):-
Objective To determine the expression of endothelin in kidneys of rats with unilateral ureteral obstruction (UUO). Methods Rats were evenly divided into two groups. Some were subjected to complete ligation of left ureter and the others with sham operation were used as control group.Four weeks later, we examined the mRNA expressions of ET-1 in kidneys of all these rats using reverse transcription-polymerase chain reaction (RT-PCR) method.The immunohistochemistry analysis was carried out to investigate the protein level of ET-1. The urinary concentration of ET-1 was determined by radioimmunoassay.Results In UUO group, the urinary concentration of ET-1 increased substantially;both gene expression and protein level of ET-1 were much higher than those in control group. At the same time, tubulointerstitial fibrosis was present in the kidneys of rats with UUO. Conclusion ET-1 is involved in the pathogenesis of the injury of UUO.
5.Significance of Renal Evaluation of Vasopressin-Deficient Brattleboro and Wistar Rats by Using Different Concentrated Gadolinium Diethylenetetramine Pentaacetic Acid Dynamic Enhanced Magnetic Resonance Imaging
jian-jun, WEN ; li, YANG ; jian-guo, WEN ; hong, ZHANG ; gui-xian, WANG ; bao-chi, LIU
Journal of Applied Clinical Pediatrics 1992;0(05):-
ObjectiveTo explore the renal functions of vasopressin-deficient Brattleboro(BB) rats by using different concentrated Gadolinium-diethylenetetramine pentaacetic acid(Gd-DTPA) dynamic enhanced magnetic resonance imaging(MRI).MethodsThe study included 14 BB rats(male rats of 3 month-old) and 14 normal male Wistar rats used as control group.Dynamic MRI was performed by using either a low dosage(0.05 mmol/kg) or a high dosage of Gd-DTPA(0.5 mmol/kg).Data of 0-60 min renal cortex,medulla and pelvic were obtained after using contrast medium.MRI of kidneys at different time was analyzed and the mean relative signal intensity(RSI) was measured.Then the RSI curves of different groups were marked.Data of each group were caculated separately by SPSS 11.0 software.ResultsThe findings demonstrated that RSI curves of the vasopressin-deficient kidneys showed different patterns as compared with those of the control group(P
7.Analysis of the relevant high-risk factors in newborns with hearing impairment.
Jian-Guo TANG ; Yi CAI ; Wen-Ya LI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(9):701-702
Female
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Follow-Up Studies
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Hearing Loss
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etiology
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Hearing Tests
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Humans
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Infant, Newborn
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Male
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Risk Factors
8.Application Investigation of Xiyanping Injections in Bone Surgery Department Inpatients in a Certain Hos-pital
Xianxi GUO ; Wen HE ; Jinchun SONG ; Jian YANG ; Jiachuan LEI
China Pharmacist 2014;(10):1720-1722
Objective:To investigate the application of Xiyanping injections ( XYP) in the bone surgery department inpatients in a certain hospital to provide reference for the clinical rational medication. Methods:A retrospective investigation was adopted to randomly survey 180 hospitalized medical recorders with XYP from a certain hospital in 2013. The usage, dosage and medication purpose of XYP were analyzed. Results:The reasonable rate of usage and dosage of XYP was 97. 2%. Among the surgical patients, 82. 8% were giv-en XYP, and among them, 97. 3% was accordance with the medication purpose. Among the nonsurgical patients, 17. 2% were given XYP, and among them, 71. 0% was accordance with the medication purpose. The alone-use rate was 60. 0% and the rate of combina-tion with antibacterials was 40. 0%. The longest treatment course was 20d, the shortest one was 1 d, and the mean value was (7. 7 ± 5. 3) d. Conclusion:Irrational use of XYP exists in clinics, and the use should be strengthened and regulated.
9.Urodynamic study of lower urinary tract function after radical hysterectomy in postoperative women of cervical cancer
Hui-Rong SHI ; Xiao-Feng YANG ; Jian-Guo WEN ;
Chinese Journal of Obstetrics and Gynecology 2000;0(12):-
Objective To investigate the characteristics of the preoperative and postoperative urodynamical parameters of women with uterine cervical carcinoma after radical hysterectomies.Methods Forty-six women had uterine cervical carcinoma at stage Ⅰ b or Ⅱ a.Complete pre-and postoperative urodynamie follow-ups were conducted for each patient.Results Twenty-six women(57%)who had preoperatively normal urinary tract function needed to void by abdominal straining after radical surgery.After the radical hysterectomy,the postvoid residual volume[(205?201)vs(5?3)ml,P
10.Effect of Foreign Plasmid DNA on Material and Energy Metabolism of Spleen in Mice
Jian-Wen LIU ; Yong-Hui SHI ; Guo-Wei LE ;
China Biotechnology 2006;0(02):-
To study the influence of foreign plasmid DNA on spleen metabolism in immune-stimulated mice via the gastrointestinal tract. Mice were oral administered by pipette with 200?g of plasmid pcDNA3 and spleen were isolated at 4h and 18h after oral administration. Total RNA were extracted from spleen and spleen gene expression profile of Balb/c mice was analyzed by using Affymetrix oligonucleotide genechip after oral plasmid pcDNA3 administration. Functional cluster analysis was conducted by Genmapp and MAPPFinder software. By functional cluster analyzing the genes which were up-regulated more than twofolds, Genmapp results showed that plenty of metabolic pathway were induced in spleen after oral administration of plasmid pcDNA3. These metabolic process included purine metabolism, pyrimidine metabolism, protein synthesis, cholesterol synthesis, fatty acid synthesis, Glycolysis, TCA cycle and mitochondria oxidative phosphorylation pathway. The similar results also took place at 18h after oral administration. The result indicated that foreign plasmid DNA can modulate metabolism process in spleen of mice via the gastrointestinal tract, and may help understand the mechanism of action of foreign plasmid DNA uptaked via the gastrointestinal tract.