1.Meta - analysis of the risk factor for endophthalmitis in patients after cataract surgery
Fei, WEN ; Bin, LI ; Fa-Wen, LI
International Eye Science 2016;16(7):1261-1264
AIM: To explore the main risk factors related to the incidence of endophthalmitis in patients after cataract surgery in China and to provide evidence for prevention.METHODS: The results of 5 studies on the main risk factors of endophthalmitis in patients after cataract surgery were analyzed by Meta-analysis method.
RESULTS: The pooled odds ratio values and 95% CI of age(≥70), diabetes, vitreous overflow, operative time ( ≥ 10min ), common operating room and control of using time of topical anesthetic were 1. 81(95% CI: 1. 43-1. 69),3. 66 (95% CI: 1. 64 - 8. 16),2. 21 (95% CI: 1. 46 -3. 32),3. 54 (95% CI: 2. 47 - 5. 06),2. 77 (95% CI: 2. 07 -3. 72),2. 09(95% CI: 1. 53-2. 86).
CONCLUSION: The main risk factors of endophthalmitis were the age(≥70), diabetes, vitreous overflow, operative time(≥10min), common operating room and control of using time of topical anesthetic.
4.Oligonucleotide Array Comparative Genomic Hybridization and Its Application
Yi-Fei PENG ; Wen-Li MA ;
China Biotechnology 2006;0(10):-
The array CGH technique (Array Comparative Genome Hybridization) has been developed to detect chromosomal copy number changes on a genome-wide and/or high-resolution scale. It is mainly used in human genetics and oncology. Generally PCR amplified bacterial artificial chromosomes (BACs) or cDNAs have been spotted on the arrays as probes. Recently, however, oligonucleotide arrays designed with more flexibility and provide much higher resolution with high sensitivity, have been successfully explored in stead of BAC array CGH and can save considerable time and efforts. There will be a gradual transition from BAC array CGH to oligonucleotide array CGH in the coming years. The combination of oaCGH and other high-through put analysis can lead to discoveries of a host of novel oncogenes, tumor suppressors as well as tumor drug resistance genes. Some major platforms of oaCGH concerning their spatial resolution, optimal probe length, sensitivity, specificity and application in recent years were compared.
6.Postoperative reconstruction of facial squamous cell carcinoma by cervicothoracic flap and temporal flap: a case report.
Fei LI ; Shuxin WEN ; Binquan WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2016;30(5):415-416
To report one case of postoperative reconstruction of facial squamous cell carcinoma by cervicotho-racic flap and temporal flap in our hospital. Clinical symptoms of the patient are facial mass and tumor ulceration.The patient had chronic bronchitis. On admission, the right side of the patient face was found to have a mass of about 6. 5 cm X 5. 0 cm, and the middle is about 2. 5 cm X 2. 5 cm X 1. 0cm ulcer, the neck has no swollen lymphnodes by palpation. After imaging and pathological examination,the patient was diagnosed as right facial squamouscell carcinoma and chronic bronchitis.
Carcinoma, Squamous Cell
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surgery
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Face
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pathology
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surgery
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Humans
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Postoperative Period
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Reconstructive Surgical Procedures
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Surgical Flaps
8.Value of magnetic resonance imaging for breast - conserving surgery
Shan GUAN ; Xinyu LL ; Wu WEN ; Fei YAN ; Zhixia LI
Chinese Journal of General Surgery 2009;24(3):200-203
Objective To evaluate magnetic resonance imaging (MRI) for breast-conserving surgery. Methods In this study, 52 cases of breast cancer eligible for breast-conserving surgery judged by traditional screening methods from May 2004 to December 2007 were inspected preoperatively with MRI in order to detect the cases of muhicentric breast cancer. At the same time, tumor size and invasive extent was measured accurately with enhanced magnetic resonance sequence combined with fat-suppression to determine the minimally extent of the surgical excision required. Results In the 52 cases of breast cancer patients, 3 cases of multicentric breast cancer and 49 cases of single breast cancer were diagnosed by MRI ,there were 3 cases with extensive intraductal carcinoma in the cases of single breast cancer. The primary negative margin rate was 93.6% (44/47) in the 47 cases with breast-conserving surgery. Conclusions MRI has thesuperiority to detect the muhicentric disease and the extensive intraductal carcinoma of breast cancer.Therefore MRI is useful in determining the indication and the extent of surgical excision of breast-conservingsurgery.
9.Colonoscopic diagnosis of gonorrheal proctocolitis
Youcai XU ; Fei LI ; Qiaosheng WEN ; Al ET
Chinese Journal of Digestive Endoscopy 2001;0(01):-
Objective To study the endoscopic manifestation of gonorrheal proctocolitis.Methods Retrospectively reviewed and analysed the clinical and endoscopic smaples of 6 gonorrheal proctocolitis cases on the findings of clinical endoscopic features,pathology,mucus smear and cultures.Results Colonoscopic features of rectum and distal sigmoid mucosa revealed varying grades of edema,congestion and abundant mucus in 6 cases;supurative secretion in 3 cases;scattered bleeding spots,local erosive and superficial ulceration in 2 cases. Pathological findings were chronic inflammation in 4 cases,local erosion,necrosis with superficial ulceration in 2 cases.Rectum mucus smear and mucus culture were positive for gonococcus in all 6 cases.Conclusion The colonoscopic and pathological features of proctocolitis merely showed the non-specific changes even in the severe cases.The gram stain and culture of rectal mucus,particularly the later,gave the highest diagnostic significance.
10.The effect and their mechanism of acid pocket in reflux esophagitis
Yedong HU ; Lu BAI ; Fei LIU ; Wen XU ; Wei LI
Chinese Journal of Digestion 2010;30(12):881-884
Objective To investigate the function of acid pocket in reflux esophagitis. Methods The 15 healthy controls and 24 reflux esophagitis patients were identified by reflux disease questionnaire (RDQ) and gastric endoscopy. The location of subjects' lower esophageal sphincter (LES) was determined by 4 channel esophageal manometry system. Then a single-channel pH electrode was positioned 1 cm below the distal border of the LES to monitor fasting pH for half an hour. After a standard meal, the pH was continuously measured for two hours. Then the electrode was moved to 5 cm above the proximal border of the LES to monitor the dynamic pH for 24 h.Results Acid pocket was found in 16 cases of reflux esophagitis patients(66.67%) and 10 cases of healthy individuals (10/15). Acid pocket occurred earlier in reflux esophagitis group than healthy controls [11.00(4.25-17.00) min vs 30.00(15.50-54.25) min, P<0.05], and the average pH value was lower [1.84(1.59-2. 19) vs 2.32 (1.96-2.71), P<0.05]. There was no statistic difference in mean pH value of gastroesophageal junction and the duration of acid pocket before the meal.Conclusion There is abnormal acid reflux in reflux esophagitis patients, and acid pocket with earlier occurrence and lower pH value may relevant to esophageal mucosal impairment.