1.Clinical analysis of 163 cases of pulmonary thromboembolism
Hua ZHANG ; Yiqiang CHEN ; Hongxia WEN ; Xiaoying ZOU ; Chen WANG
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Objective To explore the role and significance of standardized scheme for diagnosis and treatment of pulmonary thromboembolism(PTE).Methods The clinical data of 163 consecutive PTE patients who were treated in our hospital from Jan.1972 to Dec.2006 were retrospectively reviewed.The patients were divided into group A and group B based on the time of application of standardized treatment and diagnosis for PTE.The clinical data of the two groups were analyzed and compared.Results The main risk factors included deep vein thrombus,operation,injury,fracture and tumors,etc.Dyspnea was the most important clinical symptoms.The incidences of dyspnea in group A and B were 92.5% and 84.6%,respectively.The diagnostic case and the ratio of final diagnosis in group B was increased compared to those in group A on an annual basis.The median time for diagnosis was shortened(P
3.Study on transdifferentiation of renal tubular epithelial cells in patients with chronic aristolochic acid nephropathy
Wen CHEN ; Yipu CHEN ; Jing ZHANG ; Hong CHENG ; Bao DONG ; Wanzhong ZOU
Chinese Journal of Nephrology 1997;0(01):-
Objective To investigate the relationship between tubular cells transdifferentiation and renal interstitial fibrosis in patients with chronic aristolochic acid nephropathy (CAAN). Methods Specimens from renal biopsies of 10 CAAN patients with serum creatinine level of (309. 41 ? 164. 44) ?mol/L were performed to examine the extent of renal interstitial fibrosis by Masson staining, the expression of collagen types Ⅰ and Ⅲ by sirius red staining, and the expression of cytokeratin(CK), ?-smooth muscle actin (a-SMA), vimentin (Vim) and transforming growth factor-? 1 (TGF-?1) by immunohistochemical staining. Quantitative analysis by computer image analytic system or semi-quantitative analysis were used to evaluate the data. Results There was positively significant correlation between interstitial collagen types Ⅰ and Ⅲ and serum creatinine level ( r =0. 890, P
4.Delayed scanning method in multi-slice spiral CT for diagnosis of pulmonary embolism
Chuanming FU ; Wen CHEN ; Xiaohong GONG ; Lungang CHEN ; Kaihua WANG ; Jianhua ZOU
Chinese Journal of Interventional Imaging and Therapy 2009;6(4):321-323
Objective To compare different delayed scanning methods in multi-slice spiral CT angiography (MSCTA)in diagnosis of pulmonary embolism (PE). Methods Sixty patients with suspected PE were divided into three groups (A, B and C). MSCT with same Iodine concentration, injection rate, contrast medium but different delayed scanning methods was performed after injection of contrast medium. Patients in group A were examined with fixed time method (15 s), in group B with small dose-density curve method, while in group C with contrast medium track and triggering technoligy. The number, position and the shapes of emboli were evaluated with MIP, MPR and VR. Results The successful examination rate of group A was 55.00% (11/20), while of group B and C was both 100%. The coincidence rate of MSCTA compared with DSA in each group was 96.04% (291/303). Conclusion The best delayed scanning method in MSCTA for diagnosis of pulmonary embolism is contrast medium tracking and triggering technology.
5.Rhythmic changes of ambulatory blood pressures in pre-eclampsia patients
Wenxia ZOU ; Jiying WEN ; Jianmin NIU ; Lijuan LV ; Lina ZHAO ; Xiaohong LIN ; Guiying CHEN
Modern Clinical Nursing 2013;(6):9-11
Objective To study the rhythmic changes of 24 h ambulatory blood pressure in pre-eclampsia(PE)patients and come up with coping strategies. Method The levels and circadian variations of blood pressures in 240 pre-eclampsia patients were monitored and observed with 24 h ambulatory blood pressure monitoring. Results Among the 240 PE cases,121 were diagnosed as mild PE and 119 as severe PE.There were significant differences in the average of 24 h circadian variation,the average of date time variation,decreased blood pressure at night time between the two groups(all P<0.05). Conclusion Through ambulatory blood pressure monitoring,nurses can monitor the rhythmic changes of 24 h ambulatory blood pressure,make reasonable arrangements for the treatment and care operations,reduce the factors that induce eclampsia and ensure the safety of mother and baby .
6.Optimum harvest study of Gentiana crassicaulis in Ludian.
Yu ZENG ; Xing-Fu CHEN ; Yuan-Feng ZOU ; Jiu-Hua SONG ; Wen-Yu YANG ; Tao CHENG
China Journal of Chinese Materia Medica 2014;39(14):2635-2639
The paper is aimed to study the difference in yield and quality at different harvest time and determine the optimum harvest of planting Gentiana in Ludian traditional harvest period. The authors analyzed the variation in fresh weight, dry weight, dry discount rate, length, diameter, volume and the content of gentiopicroside, loganin acid, alcohol-soluble extract and total ash and made a comprehensive appraisal of yield, appearance quality and intrinsic quality by gray relational distance ideal Comprehensive Evaluation method. The results showed that there is a big difference in yield and quality both 2-year-old and 3-year-old Gentiana harvested in traditional harvest period and the comprehensive evaluation more better when harvested more later. It can be seen, Gentiana harvested the later had a better yield and quality in Ludian traditional harvest period. The harvest of Gentiana can be appropriate delayed depending on the particular circumstances of production.
Agriculture
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methods
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China
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Gentiana
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anatomy & histology
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growth & development
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metabolism
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Iridoid Glucosides
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metabolism
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Organ Size
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Quality Control
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Time Factors
7.A prospective study of endoscopic ultrasound-guided celiac plexus neurolysis for pain management in patients with pancreatic carcinoma
Xiaoping ZOU ; Suyu CHEN ; Ying Lü ; Xiaoqi ZHANG ; Wen LI ; Zhaomin XU
Chinese Journal of Digestive Endoscopy 2011;28(11):623-626
ObjectiveTo prospectively assess the efficacy and safety of endoscopic ultrasoundguided celiac plexus neurolysis (EUS-CPN) in the management of pain caused by pancreatic carcinoma.MethodsPatients with confirmed un-resectable pancreatic malignancy were treated with EUS-CPN once or twice.The data including age,gender,pain duration,opioid consumption,tumor location,pain scores before and after the procedure,number of treatment,duration of pain relief and survival time were collected.ResultsA total of 27 cases with cancerous abdominal pain were recruited.The median pain scores were significantly lower after EUS-CPN,and pain relief was obtained in 81.5% (95% CI,66.8% -96.1% ) patients with a median duration of 56.0 days (95% CI,17.1-94.9),whose confidence interval was comparable to that of survival time (97.0 days,95 % CI,82.7-111.3 ).No clinical factors could predict post-procedure duration of pain relief (x2 =6.757,P =0.239).Procedure-related transient diarrhea and fever were noted only in 1 patient.No major complications occurred.ConclusionEUS-guided CPN is safe and effective in alleviating abdominal pain associated with pancreatic cancer,even at the late stage.Moreover,no clinical factor could predict post-procedure degree or duration of pain relief.
8.Optimization of electroporation parameters in HL-60 cells for STIM1 siRNA interference during its differentiation.
Hai-Yang CHEN ; Wen-Ying ZOU ; Cui-Hua XIE ; Xiao-Jing MENG ; Chun-Qing CAI
Chinese Journal of Applied Physiology 2011;27(4):497-499
Cell Transformation, Neoplastic
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drug effects
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genetics
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Dimethyl Sulfoxide
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pharmacology
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Electroporation
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methods
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HL-60 Cells
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Humans
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Membrane Proteins
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genetics
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Neoplasm Proteins
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genetics
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RNA Interference
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RNA, Small Interfering
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genetics
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Stromal Interaction Molecule 1
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Transfection
9.Expression of KiSS-1,matrix metalloproteinase-9,nuclear factor-?Bp65 in ovarian tumour
Guo-Lan GAO ; Li-Dan LIU ; Xue-Sen ZOU ; Wen-Xue CHEN ;
Chinese Journal of Obstetrics and Gynecology 2001;0(01):-
0.05).The expression of NF-?Bp65 protein in epithelial ovarian cancer was significantly correlated with FIGO stage(P0.05).There was obviously negative correlation between KISS- 1 and MMP-9 expression in ovarian cancer(rs=-0.547,P
10.Endoscopic submucosal dissection in patients with high grade intraepithelial neoplasia and/or early cancer of remnant stomach after partial gastrectomy
Tingsheng LING ; Guangxia CHEN ; Lei WANG ; Xiaoqi ZHANG ; Xiaoping ZOU ; Wen LI ; Zhaomin XU
Chinese Journal of Digestive Endoscopy 2015;32(7):427-431
Objective To evaluate the feasibility,safety and efficacy of ESD for precancerous lesions and early cancer of remnant stomach after partial gastrectomy.Methods ESD was performed in 11 cases of high grade intraepithelial neoplasia/early cancer of remnant stomach.The short-term and long-term indices including time of procedure,complication,En Bloc resection rate,R0resection rate,local recurrence rate as well as lymph node metastasis were recorded and analysed.Results ESD was completed in all patients with only one case of delayed massive bleeding which was controlled by endoscopy successfully.Average procedure time,En Bloc resection rate,R0 resection rate were 85.5 minutes,100% and 90%,respectively.No local recurrence or lymph node metastasis was detected during post-ESD surveillance (15 ~ 51 months).Conclusion High grade intraepithelial neoplasia and early cancer of remnant stomach after partial gastrectomy might be indication for ESD because of its safety and definite effect.Additionally,careful management of the fibre tissue is the key to procedure success.