1.Analysis of Viral Etiology in 3 572 patients with Acute Respiratory Tract Infections
International Journal of Laboratory Medicine 2015;(20):3002-3004
Objective To explore the viral etiology of acute respiratory tract infections in Nanping area .Methods A total of 3 572 patients ,suffered from acute respiratory tract infections from December 2012 to December 2014 were enrolled in the study .Sev‐en common respiratory viruses were detected by direct immunofluorescence assay ,including influenza A virus(IA) ,influenza B virus (IB) ,adenovirus (ADV) ,respiratory syncytial virus (RSV) ,arainfluenza type Ⅰ (P1) ,arainfluenza type Ⅱ (P2) ,arainfluenza typeⅢ (P3) .Results In total 3 572 samples ,509 samples were virus positive (14 .25% ) .Among them ,507 positive samples were single virus infections and 7 positive samples were double virus infections .RSV infection(9 .38% ) ,P3 infection(2 .32% ) and IA infection (1 .09% ) rates were the top three .Conclusion RSV was the main viral pathogen among 7 common respiratory viruses with obvious seasonal periodicity .Children′s immunity is low and need to prevent respiratory viral infections .
2.Intervention Measures of Nosocomial Infection in Hospitals of Hunan Province:An Evaluation on Implementation
Chinese Journal of Nosocomiology 2009;0(16):-
0.05).The usage rate of antimicrobial agents in inpatients and outpatients was 74.65% and 45.52% respectively,with a significant difference(P
3.Analysis on the knowledge of non-communicable disease among general practitioners in the community
Yan QIU ; Ying LIU ; Wen REN ; Bing WANG ; Jingjing REN
Chinese Journal of Health Management 2016;10(3):188-191
Objective To better promote the health education and health promotion among patients with chronic disease, general practitioners (GPs) in the community should master the knowledge of non-communicable diseases (NCDs). This paper aimed to describe the current situation of GPs' knowledge about prevention and treatment of NCDs. Methods Self-designed questionnaires were issued to 1 077 GPs in community health service centers, and all GPs finished the questionnaire without assistance. The content of questionnaire includes the general information of GPs and six questions focusing on NCDs. Results Overall, 1 076 GPs completed the questionnaire, and the response rate was 99.9% (1 076/1 077). With regard to the six questions about NCDs, 90.4% (973/1 076) of GPs were well aware of the diagnosis of hypertension. Apart from that, the knowledge of diabetes mellitus (60.9%, 655/1 076), factors related to NCDs (70.2%, 755/1 076), the concepts of mental illness (52.0%, 560/1 076) and the clinical significance of tumor markers (87.9%, 946/1 076) among GPs were adequate, while more than half of the GPs did not know a lot about home oxygen therapy. Conclusion The mastering level of knowledge about prevention and treatment of NCDs among GPs varies that they need further improvement.
4.Current status and development of the training of general practitioners with special interest (GPSI) in China
Ying LIU ; Yan QIU ; Wen REN ; Jingjing REN
Chinese Journal of Medical Education Research 2021;20(4):406-408
In recent ten years, general practitioner (GP) training and practice develops rapidly in China. It has established a relatively complete GP training system, including medical college education and standardized residency training. However, the path of continuing professional development and clinical skills improvement for GP after standardized residency training is still unclear. The concept of GP with special interest (GPSI) has been proposed these days, and it has put forward a new development direction for the career path of GP. In this article, on the basis of understanding the current status of GPSI in China, we try to discuss its advantages and problems, and then propose our suggestions for its future development.
5.Advances in research on RNA interference-related drugs for cancer treatment.
Chinese Journal of Oncology 2012;34(11):801-804
Animals
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Antineoplastic Agents
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therapeutic use
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Gene Silencing
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Genetic Therapy
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methods
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Humans
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MicroRNAs
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antagonists & inhibitors
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therapeutic use
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Neoplasms
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genetics
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therapy
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RNA Interference
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physiology
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RNA, Small Interfering
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antagonists & inhibitors
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therapeutic use
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RNA-Induced Silencing Complex
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metabolism
6.Effects and safety of low moleculer weight heparin on treatment of nephrotic syndrome
Hong REN ; Nan CHEN ; Wen ZHANG
Chinese Journal of Practical Internal Medicine 2001;0(09):-
Objective\ To investigate the effect and safety of LMWH on treatment of nephrotic syndrome(NS).Methods\ We randomized 43 patients with primary NS into 2 groups.Steroid and cyclophosphamide were given in control group.LMWH with the dosage of 3200~5000IU twice per day was added in the treated group.Results\ After 4 to 6 weeks of treatment,a significant increase in AT-Ⅲ,anti-Xa activity and serum albumin and decrease in fibrinogen and proteinuria were observed in LMWH.Conclusion\ LMWH should be recommended as a useful treatment of NS.
7.Diagnosis and treatment of deep vein thrombosis and pulmonary embolism in nephrotic syndrome
Wen ZHANG ; Nan CHEN ; Hong REN
Chinese Journal of Practical Internal Medicine 2001;0(09):-
Objectives To investigate the incidence of deep vein thrombosis (DVT) of lower limbs and pulmonary embolism (PE) caused by hypercoagubility in patients with nephrotic syndrome and to estimate the indication and clinical effect of anticoagulation therapy. Methods 54 patients with nephrotis syndrome(thirty-one males and twenty-three females with mean age: 44 13?15 88, 24 hours proteinuria:8 43?5 64g, albuminemia: 20 48?5 41g/L) were enrolled in this study.DVT of lower limbs and PE were confirmed by radionuclide imaging (RNV) with 99mTc-MAA and the clinical effect of subcutaneous injection of low molecular weight heparin (LMWH) and oral antiplatelet coagulation therapy were evaluated as well. Results 41 out of 54 cases (76%) had DVT of lower limbs, 14 8% of which had clinical manifestations. 32 out of 54 cases (59 25%) had PE, 7 4% of which had symptoms. 70 7% of PE were caused by DVT of lower limbs. No patient died of PE after the LMWH treatment.Conclusions DVT is one of the most important complications of NS. RNV can be used to make early diagnosis of DVT of lower limbs and PE. Early anticoagulation therapy might ameliorate the prognosis of NS and lower the mortality of PE.
8.Investigation and analysis on teaching evaluation of professional teachers in military medical university
Juan LU ; Shihao WEN ; Weimin REN
Chinese Journal of Medical Education Research 2005;0(05):-
The course arrangement,teaching contents and means and other items were investigated and analyzed in this research of teaching evaluation of professional teachers in military medical university.The results showed that the levels of post-oriented education teaching were increasing in updating ideas and accumulating experiences in recent years.However,there still existed a few problems such as too much basal theories,lack of real army circs in the contents and little practice in the manners.Therefore,the quality of post-oriented education in military medical university is expected to be developed to a higher level.
9.Studies on antiarrhythmic portion in Cornus officinalis extract
Lantong ZHANG ; Leiming REN ; Jinkun WEN ;
Chinese Traditional and Herbal Drugs 1994;0(11):-
Object To study the effective portion in Cornus officinalis Sieb. et Zucc. extract (COE) for the treatment of arrhythmia. Methods Effect of COE on chloroform induced ventricular fibrillation in mice and electrophysiology of isolated guinea pig papillary muscle were studied. Results Antiarrhythmic effect of COE may be related to its prolongation of action potential duration, increase of the absolute value of resting potential and a decrease of autonomy of sinus node. The effective portion in COE may be its total organic acid and a certain yet unknown trace substance, whereas its total glycosides were devoid of such activities. Conclusion Pharmacodynamic and myocardial electrophysiologic studies showed that the total organic acid and a certain unknown trace substance possessed the obvious antiarrhythmic activity.
10.Analysis of the Curative Effect of Interventional Therapy for Cervical Cancer
Xiaoyan WEN ; Fengqi REN ; Yi WANG
Journal of Practical Radiology 2001;0(07):-
Objective To evaluate the effect of operation associated with uterine arerial chemotherapy and embolization preoperation.Methods 31 patients with pathologically confirmed cervical carcinoma were treated with interventional therapy,followed by uterectomyandpelvic lymphadenectomy.Results Curative effect was obvious.The lymph metastasis of Ⅱ and Ⅲ stage was 12% and 66.67%respectively.27 patients followedup for 3 years,23 were survived(85.19%).Conclusion For cervical carcinoma,before operation,the interventional therapy can reduce the size of tumor and the metastasis of lymph,improve the ectomy by operation and the survival rate.