1.Anorectal motility in children with functional constipation.
Jie-Yu YOU ; Hong-Mei ZHAO ; Wen-Xian OU-YANG
Chinese Journal of Contemporary Pediatrics 2010;12(11):915-917
Adolescent
;
Anal Canal
;
physiopathology
;
Child
;
Constipation
;
physiopathology
;
Female
;
Gastrointestinal Motility
;
physiology
;
Humans
;
Male
;
Rectum
;
physiopathology
2.Clinical teaching for non-special medical practitioner in the department of pediatric hematology
Jianwen XIAO ; Xianhao WEN ; Ying XIAN ; Jie YU
Chinese Journal of Medical Education Research 2013;(11):1168-1170
The common problems for non-special pediatric medical practitioners in the depart-ment of hematology include short-time of rotation, weak foundation of pediatric hematology and low enthusiasm of learning. The entrance education was highlighted in order to make refreshers familiar-ize with the severity of illness and eliminate the medical error. Basic theoretical study was strength-ened aiming at improving clinical skill and enhancing the learning interesting. Method of doctor-patient communication was reformed to reduce medical disputes.
3.Coccidioidomycosis in an infant.
Wen-xian OUYANG ; Jie-yu YOU ; Yi-min ZHU
Chinese Journal of Pediatrics 2008;46(12):934-935
Coccidioides
;
Coccidioidomycosis
;
pathology
;
Humans
;
Infant
;
Male
4.Value of electronic colonoscopy in the diagnosis of childhood chronic diarrhea.
Jie-Yu YOU ; Chan-Bin CHEN ; Wen-Xian OU-YANG
Chinese Journal of Contemporary Pediatrics 2007;9(5):493-494
Adolescent
;
Child
;
Child, Preschool
;
Chronic Disease
;
Colonoscopy
;
methods
;
Diarrhea
;
diagnosis
;
pathology
;
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Male
5.How to Cultivate the Pediatrics Interns' Clinical Work Ability
Xian-Hao WEN ; You-Hua XU ; Jie YU ; Ying XIAN ; Yong-Chun SU ;
Chinese Journal of Medical Education Research 2006;0(10):-
The internship is the transition period of a medico becoming a doctor,the cultivation of clinical work ability of interns is a comprehensive ability cultivation which includes the foundation theories' consolidation and use,the practical operative train- ing,the cultivation of clinical thought ability and communication between doctors and patients,etc.To educate pediatrics intern has its characteristics.
6.Pediatric Shwachman-diamond syndrome: report on 5 cases and literature review.
Xian-Hao WEN ; Jian-Wen XIAO ; Jie YU ; Ying XIAN ; Xian-Min GUAN ; Yu-Xia GUO
Chinese Journal of Contemporary Pediatrics 2013;15(11):970-974
Bone Marrow Diseases
;
diagnosis
;
genetics
;
therapy
;
Child, Preschool
;
Exocrine Pancreatic Insufficiency
;
diagnosis
;
genetics
;
therapy
;
Female
;
Humans
;
Infant
;
Lipomatosis
;
diagnosis
;
genetics
;
therapy
;
Male
;
Mutation
7.CT scan findings of primary pulmonary non-Hodgkin's lymphoma and their relation to pathological features.
Wen-jie LIANG ; Xian-yong ZHOU ; Shun-liang XU
Journal of Zhejiang University. Medical sciences 2009;38(2):199-203
OBJECTIVETo investigate the CT scan findings of primary pulmonary non-Hodgkin's lymphoma (PPNHL) and their relation to pathological features.
METHODSThe CT scan findings of 17 PPNHL cases confirmed pathologically from August 1992 to June 2007 were analyzed in relation to their pathological foundation.
RESULTIn 17 cases the CT findings showed: 1) Five were single mass or nodule, including 3 with air-bronchograms, 1 with straddling-lobe distribution and 3 with slight enhancement; 2) One was multi-nodules with air-bronchograms; 3) Six were consolidation with air bronchogram,including 3 with straddling-lobe distribution and 3 with slight enhancement; 4) Five were combined changes, including 5 with air-bronchograms, 2 with straddling-lobe distribution and 4 with slight enhancement. The CT features of PPNHL corresponded to their pathological process and pathological features.
CONCLUSIONPrimary pulmonary non-Hodgkin's lymphoma should be considered when CT scan shows variety of images found in one patient, middle lobe of right lung involved, air-bronchograms and straddling-lobe distribution in consolidation with slight enhancement.
Adult ; Aged ; Female ; Humans ; Lung Neoplasms ; diagnostic imaging ; pathology ; Lymphoma, Non-Hodgkin ; diagnostic imaging ; pathology ; Male ; Middle Aged ; Tomography, X-Ray Computed
8.Study on Mutation in Exon 8 of ATP7B Gene in Chinese Patients with Wilson Disease
xian-ting, JIAO ; xiao-qing, LIU ; ya-fen, ZHANG ; jie, WU ; lian-wen, WANG
Journal of Applied Clinical Pediatrics 2004;0(08):-
G,the noval insertion mutation of c.2298_2299insC is identified in Chinese patients.
9.The clinical analysis of 51 taxi drivers with peptic ulcer.
Wen-wen LUO ; Jie ZHAO ; Yun-xian FU ; A-huo MA
Chinese Journal of Industrial Hygiene and Occupational Diseases 2012;30(2):131-132
OBJECTIVETo explore the main pathogenic factor causing the peptic ulcer of taxi drivers, which provide the basis for its prevention.
METHODS98 taxi drivers were inspected by electronic endoscopy, according to the inspection all cases were divided into ulcers group and normal group. Then various factors were statuses by the logistic regression analysis according to the results of questionnaire.
RESULTSThe prevalence of peptic ulcer of taxi drivers was 52.0%, and logistic regression analysis showed that dining time, taste spicy, meals temperature, smoking,alcohol, mental stress, HP infection and stomach health knowledge were statistically significant (P < 0.05), which would be the risk factors for peptic ulcer of taxi drivers.
CONCLUSIONBy emphasis on diet and lifestyle adjustments, stress regulation on the basis of eradication of HP infection will help the prevention and treatment of peptic ulcer of the taxi driver.
Adult ; Automobile Driving ; Female ; Humans ; Male ; Middle Aged ; Occupational Diseases ; epidemiology ; Peptic Ulcer ; epidemiology ; Prevalence ; Risk Factors ; Surveys and Questionnaires ; Young Adult
10.Effects of combined arsenic trioxide and resveratrol on the viability of human acute promyelocytic leukemia cell line NB4 cells
Jin-ling, YU ; Kai-wen, HE ; Wen-feng, CHU ; Xian-mei, PIAO ; Guo-fen, QIAO ; Yan-jie, L(U)
Chinese Journal of Endemiology 2011;30(1):9-12
Objective To investigated the effects of combined arsenic trioxide(ATO) and resveratrol(Res)on the viability of NB4 human leukemia cells. Methods NB4 human leukemia cell was used in this experiment.Cells were cultured in ATO (0,0.1875,0.3750,0.7500, 1.1250, 1.5000,2.2500,3.0000,5.0000 μmol/L) and Res (0, 1.5625,3.1250,6.2500, 12.5000, 18.7500,25.0000,37.5000,50.0000 μmol/L). Cell viabilities were measured by MTT in different treatment groups. Half inhibitory concentration(IC50) was calculated. The ratio of concentration of ATO and Res 1.5∶ 18,1.5∶ 25,1.5∶ 35 was added to cells, and the combination index(CI) was calculated. The level of ROS in control, ATO( 1.5000 μmol/L), Res(25.0000 μmol/L) and ATO(0.9000 μmol/L) + Res( 12.5000μmol/L) groups was measured by chemiluminescence assay. Results ①ATO( ≥0.7500 μmol/L) reduced the viability of NB4 cells in a concentration-dependent manner(P < 0.05 ), and IC50 was (1.78 ± 0.11 )μmol/L. ②)Res (≥18.7500 μ mol/L) dose-dependently decreased the viability of NB4 cells (P < 0.05 ), and IC50 was ( 18.71 ±0.18)μ mol/L. ③Combination of ATO and Res showed an antagonistic effect on NB4 cells viability. ④The ROS in Res group( 1670.55 ± 13.97) was significantly lower than that in control group(2345.88 ± 14.48,P < 0.05). The ROS in ATO group (3092.42 ± 94.84) was significantly higher than that in control group(P < 0.05). The ROS in ATO + Res group (1860.27 ± 15.99) was significantly lower than that in ATO group(P < 0.05). Conclusions NB4 cell survival rate can be decreased by ATO and Res. The combination of arsenic trioxide and Res presents an antagonistic effect on NB4 cell viability, in part by reducing intracellular ROS formation.