1.Evaluation for embryonic stem cell study with the theory of Marx's ethics
Chinese Journal of Medical Education Research 2011;10(1):126-128
Stem cell has a prospective future in cells therapy.However,the harvesting of stem cells is a paradoxical issue.In fact.the essence of dispute on stem cell studies is a combat between utilitarianism and moralism.The point of view of Marx's Ethics about stem cell studies present dialectical harmony between utilitarianism and moralism.The development of an embryo is a developing process from cell mass to natural persons.but not social persons which have characteristics of sociality and consciousness.Embryo is not completely a person,so embryonic stem cell harvesting is consistent with Marx's Ethics.But the timing of harvesting stem cells and the way to deal with the embryo need further discussion.
2.The abnormity of hypothalamus-pituitary-hypothyroid axis in cerebral infarction onset and its significance
Journal of Chongqing Medical University 2008;0(S1):-
Objective:To find the effect of the abnormity of hypothalamus-pituitary-hypothyroid axis on cerebral infarction onset. Methods: Objects were divided into 3 groups: cerebral infarction group(CIG)、persons with cerebral infarction risk factor group(CIRG) and control group(CG) .The concentration of serum T3、T4、TSH、TGA and TMA on an empty stomach in each group were measured respectively by radioimmunoassay,and results were compared between each two groups by using Student t test. Results:Compared with CIRG and CG,the levels of T3、T4 in the sample of CIG were lower,and the level of TSH were higher,and there was distinctly difference(P0.01). Conclusion:This study indicated that the function of hypothalamus-pituitary-hypothyroid axis was abnormity in patients with cerebral infarction and those persons with cerebral infarctive risk factor.
3.Clinical Observation on the Treatment of Infantile Viral Myoearditis with Huangqi Injection united Vitamin C
International Journal of Traditional Chinese Medicine 2009;31(3):250-251
Objective To observe the clinical effects of treating infantile viral myocarditis with Huangqi Injection united Vitamin C. Methods 60 patients with infantile viral myocarditis were randomly recruited into a control group and a treatment group, with 30 patients in each group. Both groups were given comprehensive therapies including rest, anti-infection, myocardium nourishment, etc. The treatment group was additionally treated with Huangqi Injection united Vitamin C on the basis of comprehensive therapies. Results The total effective rate of the control group and the treatment groups was 70.00% 96.67% respectively, the difference showing statistic significance (P<0.05) . Conclusion It was effective to treat infantile viral myocarditis with Huangqi Injection united Vitamin C.
4.Study of correlation of diabetic nephropathy with serum endothelin(ET-1) and C-reactive protein(CRP)
Chinese Journal of Diabetes 2009;17(11):842-843
Objective To investigate the relationship of diabetic nephropathy with serum endothelin-1(ET-1) and C-reactive protein(CRP). Methods Levels of blood pressure, glucose, lipid, creatinine,ET-1,CRP and urinary albumin excretion(UAER) were measured and calculated in 86 patients with type 2 diabetes mellitus(T2DM)and 30 healthy subjects. Results Serum ET-1 and CRP were significantly higher in T2DM than in control(P<0.05,P<0.01).Serum ET-1 and CRP were increased with increment of serum creatinine and UAER(P<0.05,P<0.01). Conclusions Serum ET-1 and CRP may be involved in the development and progression of diabetic nephropathy.
5.Influence of electroacupuncture on somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To explore influence of electroacupuncture on somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats.Methods The double-label immunofluorescence with confocal microscope was used to observe somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats after electroacupuncture stimulation of Dazhui (GV14)' and Baihui (GV20)' in DuMai.Results Somatostatin expression of newborn neurons was found in the hippocampus.Moreover,in somatostatin expression of newborn neurons,epileptic rats with electroacupuncture had less than epileptic rats in the hippocampus.The former had an obviously significant difference compared with the latter (P
6.RELATIONSHIP BETWEEN MALIGNANT GRANULOMA AND MALIGNANT LYMPHOMA
Chinese Journal of Radiation Oncology 1995;0(02):-
This study was to compare 104 cases of malignant midline lymphoma with 69 cases of malignant granuloma in their clinical course, initial symptoms, location of lesion, extension of disease, treatment and prognosis. The two groups were similar in sex and median age. As regard to the initial symptoms such as nasal obstruction, epistaxis and nasal discharge, they were present in more than half of the patients in both groups. The primary location of lesions was in the nose (60% in both groups). As the Ann Arbor staging system is unsuitable for this disease, we compared the treatment results by area of involvement. Treatment: 74% of malignant midline lymphoma was treated by radiation and chemotherapy. 27% of malignant granuloma was treated by chemotherapy. The radiation of the two groups were 45~55Gy and 50~60Gy, respectively. The 5-year survival rates were over 90% in both groups, for those of lesion with one area involvement, 87.8% and 68% for lesions with two area involvement. 52.3% and 51.5% for three area involvement, 26.6% and 29% for four area involvement patients. Besides local uncontrol, the failure was extra-nodal invasion, such as subcutaneous nodules, pleura-peritoneal or bone marrow extensions. The authors believe that these two groups of lesions actually belong to one disease entity.
7.Clinical Observation on the Treatment of 34 Cases of Infantile Anaphylactoid Purpura with Self-made Huoxue Huayu Decoctoin
International Journal of Traditional Chinese Medicine 2009;31(4):333-
Objective To observe the effect of treating infantile anaphylactoid purpura with self-made Huoxue Huayu decoction. Methods 68 cases with infantile anaphylactoid purpura ,were randomly recruited into a control group and a treatment group, with 34 cases in each group. The control group was taken Cetirizine, Prednisone, Rutin and Vitamin C orally. The treatment group was treated with self-made Huoxue Huayu decoction on the basis of treatment in the control group. Results The total effective rate of the control group and the treatment group was 82.35% and 94.12% respectively. As compared with the effective rate in the control group, the treatment group showed significant improvement. Conclusion It was effective to treat infantile anaphylaetoid purpura with Huoxue Huayu decoction.
8.Gene polymorphisms predict efficacy and toxicity of chemotherapy for colorectal cancer
Tumor 2010;(2):164-169
Objective:The efficacy and toxicity of anticancer drugs differ in different tumor patients. It could not meet the requirements of optimization of tumor treatment if only under the guidance of clinical and pathologic characteristics. More and more attention is focused on individualized therapy based on individual gene profiles. It has been identified that gene polymorphisms are responsible for different outcomes of individuals. Gene polymorphisms, including sequence polymorphism and single nucleotide polymorphism, will decrease the clinical efficacy of chemotherapeutic drugs or increase adverse reactions by influencing the expression or activity of the corresponding proteins. In recent years several gene polymorphisms related to drug metabolism, transportation, or inactivation may affect the outcomes of chemotherapy and the frequency of adverse reactions. Identification of the polymorphism genes is important for individual therapy for tumor patients.
9.Training mode requirement analysis on in-service postgraduateswho major in health service management
Chinese Journal of Medical Education Research 2014;13(10):980-984
Objective To provide references for enhancing the connection between the need of society and the training mode of in-service postgraduates who major in health service management by analyzing the existing and potential in-service postgraduates' potential trainingwishes andexpectations.Methods Questionnaire surveys,which involved basic information,motivations and aspirations on the advanced studies,understandings and suggestions on the cultivating mode,were conducted among in-service postgraduates(Grade 2010 through Grade 2012) who major in health service management in BUCM and staffs in the departments of corresponding postgraduates.Data including 128 validated questionnaires were analyzed using descriptive statistics in excel.Results The data indicated that further education was welcomed by 87 in-service postgraduates(85.3% of the survey samples),who had astrong willing to further study.Specifically,the following tendencies were obtained:interdisciplinary training combining research and practice was approved by 71 in-service postgraduates (55.5% of the samples); career-oriented talent training mode was accepted by 90 in-service postgraduates(70.2% of the samples); 79 in-service postgraduates (61.7% of the samples) believed courses should include both theory and practice educations; flexible educational system was welcomed by 77 in-service postgraduates(60.0% of the samples) ; 61(47.7%) in-service postgraduates wished to attend class on week-ends while 45 (35.0%) wished to attend class in evenings; group instruction method was recommended by 73(57.0%) in-service postgraduates; 104(81.3%) believed double-tutors system should be applied to academic dissertation,and the academic dissertation could be all kinds of research papers such as investigation report,which was approved by 97 (75.6%) in-service postgraduates.Conclusions Through the above analysis,it can be validated that education on in-service postgraduates who major in health service management is worthy of further development.Finally,colleges and universities are suggested to optimize the training mode in four aspects including training objective,curriculum provi-sion,teaching methods and graduation thesis.
10.The effect evaluation of bronchodilation agents in the treatment of childrens with airway hyperresponsive dis-ease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(z1):1-3
Objective To objectively evaluated of the efficacy of bronchodilation agent by using pulmonary function .Methods 104 childrens with airway hyperresponsive diseases who saw doctor at the Guangdong Women and Children′s Hospital,aged 0~6 years.They were classified into three groups:salbutamol group(n=36);ipratropium bromide group(n=32) and two drugs group(n =36).Each group received salbutamol or ipratropium bromide or both.Then tidal breathing flow-volume loop and parameters were obtained before and after aerosol inhalation to evalu-ate the effects of drugs .Results There were significant improvement in each group after the inhalation of bronchodi -lators.Conclusion The two drugs of Salbutamol and ipratropium bromide can be used as the selective drugs of bron -chodilation .