Adult ; Bronchoalveolar Lavage ; Humans ; Male ; Middle Aged ; Pneumoconiosis ; complications ; therapy ; Pulmonary Disease, Chronic Obstructive ; etiology ; therapy ; Treatment Outcome

Objective To research the occurrence of liver cirrhosis and portal hypertension splenectomy treatment,and analyze the risk factors for postoperative complications.Methods Retrospectivly analyzed the clinical data of 390 liver cirrhosis cases from March 2009 to May 2013 who were admitted to department of digestion and vascular surgery,First Affiliated Hospital of Xinjiang Medical University,for splenic resection.Child classification,diabetes,amount of fluid drainage,drainage time,blood loss,emergency surgery,combined with other surgery were alalysised by Logistic regression.Results Among three hundred and ninty cases of splenectomy patients,liver cirrhosis complications occurred in 53 cases (53/390,13.58％).In these 53 cases,45 cases combined diabetes,Child grade A 12 cases,B 22 cases,C 19 cases,and theirs 24 hours drainage volume was (422.45 ±297.09) mL,drainage time was (4.96 ± 1.48) d,blood loss was (874.72 ± 106.19) mL,K value was 0.10 ±0.06,R15 value was 0.27 ±0.016,albumin concentration was (30.09 ±6.87) g/L,Among the rest 337 cases,228 cases were combined diabetes,Child grade A 134 cases,B 129 cases,C 74 cases,and theirs 24 hours drainage volume was (234.06 ± 171.15) mL,drainage time was (3.18± 1.72) d,blood loss was (261.90±98.27) mL,K value was 0.14 ± 0.09,R15 value was 0.19 ± 0.015,albumin concentration was (32.51 ±5.58) g/L.Multivariate regression analysis had indicated that Child grade,drainage volume of 24 hours,drainagetime,and K value were independent factors affecting the occurrence of complications.Conclusion The major risk factors of incidence happen on postoperative complications in cirrhosis and portal hypertension splenectomy are high Chill grading,draining a long time,and 24 hours blood loss,and k value.

Objective To explore the application of empowerment theory in health education for patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods 68 patients were allocated into the intervention group and the control group with 34 patients in each group.The intervention group received health education guided by empowerment theory and the control group received only traditional health education.Coronary heart disease empowerment scale was recorded before and after intervention for both groups.Clinical symptoms and coronary angiography were observed 6 months after PCI for both groups.Results The total coronary heart disease empowerment scale score and all subscales of the intervention group were improved after intervention,as well as the control group.After 6 months,rate of angina pectoris and the rate of restenosis examined by coronary angiography were lower than those of the control group.Conclusions The health education guided by empowerment theory can effectively improve the psychosocial status as well as the long-term effect of PCI.

Aged ; Female ; Humans ; Joint Dislocations ; etiology ; surgery ; Joints ; surgery ; Laryngeal Cartilages ; surgery ; Laryngoscopy ; methods ; Male ; Middle Aged ; Treatment Outcome

China ; Hepatitis A ; immunology ; prevention & control ; Humans ; Immunization ; methods

Objective: To investigate the CT perfusion (CTP) imaging for evaluation of hemodynamic changes in patients with internal carotid stenosis before and after the medication and stenting. Methods: Forty patients with severe unilateral internal carotid stenosis (ipsilateral stenosis > 70%, contralateral stenosis < 30%) were detected by CT angiography (CTA) and conformed by digital subtraction angiography (DSA), CTP imaging was performed at the same time. Twenty-two patients with good vascular compensation at the ischemic sites and with no significant delay in blood flow were treated with medication (aspirin 100 mg, clopidogrel 75 mg and atorvastatin 20 mg daily). CTA and CTP were performed again after one year. Stenting was performed in the other 18 patients without vascular compensation or inadequate compensation and significantly delayed in blood flow, and then they took anti-platelet aggregation and plaque stable drugs (the same as the medication group). The relative perfusion parameters including regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV), regional mean transit time (rMTT), and regional time to peak (rTTP) in both groups (including the examination on admission and reexamination after one year) were compared. All the absolute perfusion parameters of the ipsilateral and contralateral sides in the operation group (including before the procedure, 7 days and one year after the procedure) were also compared. Results: Circled digit one All the relative perfusion parameters before medication and before operation were compared. In addition to rCBF (0.86 ± 0.18; 0.42 ± 0.26) and rCBV (1.02 ± 0.03; 1.15 ± 0.06), there were no significant difference in other parameters (P > 0.05). Circled digit two All the relative perfusion parameters after taking medicine for one year in the medication group and one year after the procedure in the operation group were compared. In addition to rCBF, there were significant differences in other parameters (P < 0.05). Circled digit three TTP and MTT were delayed on the ipsilateral sides before the procedure, and CBF were decreased to various degrees in 18 patients in the operation group, compared to the contralateral sides, there were significant difference. Seven days after the procedure, CTP imaging showed that CBF was improved significantly, and TTP and MTT were still delayed. In comparison with the ipsilateral and contralateral sides one year after the procedure in CTP imaging, there were no significant differences among TTP, MTT, CBF, and CBV. The comparative analysis of the absolute parameters at 3 time points were performed, and there were significant differences in the changes of TTP, MTT, and CBF on the ipsilateral sides (P < 0.05). Circled digit four After the medication group were followed up for 1 year, there were two new patients with TIA, and one of the two patients improved before the treatment. Eighteen patients in the operation group were followed up for one year after the procedure, and there were no new patients suffered TIA. Among the 16 patients with TIA before the procedure, 9 improved, and there were significant differences before and after the procedure (P < 0.05). Conclusion: CTP imaging can accurately reflect the medication and hemodynamic conditions of patients with internal carotid stenosis before and after stenting, According to the related parameters in combination with the clinical and DSA results, it has the guiding role for reasonable choice of surgical indications and objectively evaluate the efficacy and prognosis.

Adult ; Epiglottis ; Humans ; Laryngeal Neoplasms ; pathology ; surgery ; Male ; Neoplasm Recurrence, Local ; Sarcoma, Synovial ; pathology ; surgery

Dental Porcelain ; classification ; therapeutic use ; Humans

Objective To evaluate the renal function response to vasopressin in obstructed and non-obstructed kidney in vasopressin-deficient rats by using dynamic enhanced MRI. Methods This study included 26 vasopressin-deficient Brattleboro(BB)rats.Unilateral ureteral obstruction(UUO) model was set up in 12 BB rats.After releasing UU0 24 h,treatment of AVP was given in 7 non-obstrueted and 7 obstructed BB rats for 6 d.Seyen normal Wistar rats and 7 BB rats were used as control.Dynamic enhanced MRl was performed at 0-60 min following the administration of GadoliniumDTPA(0.05 mmol/kg)and the mean relative signal intensity(RSI)was measured. Results BB rats RSI increase occurred during the first minute,with a maximum mean RSI of(149±10)%in cortex,(155±13)%in medulla and(146±13)%in pelvis.Then,a gradual decrease in the cortical RSI occurred,after which a small increase was observed in Phase 3.BB rats RSI patterns were different from Wistar rats.After AVP treatment,mean RSI of BB rats in cortex,medulla and pelvis reached a maximum of(180±6)%,respectively at 30 sec,followed by a fast decrease at 1 min.Then,RSI decreased gradually.Phase 3 demonstrated a moderate increase in medullary and a relative large increase in pelvic RSI until 30 min after injection,after which RSI returned to baseline.BB rats RSI patterns after AVP treatment were similar to that of Wistar rats.Cortical,medullary and pelvic mean RSI increased slowly compared to non UUO rats.In phase 3,mean RSI of all segments decreased gradually.UUO rats RSI patterns were different from non UUO rats.After AVP treatment in UUO rats,mean RSIs of all segments increased faster compared to UUO rats without AVP.Cortical mean RSI reached a maximum of(193±7)% at 2 mim Mean RSI of medulla were unchanged,but the pelvic mean RSI deereased gradually to a minimum of(77±5)%at 5 min.Phase 3 was characterized by a slight recovcry of all RSIs.UUO rats RSIs were recovered after AVP treatment.The renal blood flow(RBF)of UUO rats was decreased to(1.1±0.1)m1·min-1·100g-1,wherease the RBF was increased to (1.9±O.3)ml·min-1·100g-1 after injecting AVP. Conclusion Dynamic enhanced MRI may provide useful information for distinguishing between kidneys having changes in the renal vasopressin concentration and the kidneys suffer from the obstructed renal damage.

Objective To study the incidence of PTEN, p53 and Ki-67 expression in astrocytoma and show the relationship between PTEN, p53 expression and the proliferation activity. Methods The surgical specimens from 68 brain astrocytoma patients were analysed to detect PTEN, p53 and Ki-67 expression with immunohistochemical method. Results The incidence of PTEN, p53 and Ki-67 expression was 54.4 %,45.6 % and 48.5 % respectively in astrocytoma. With the grade of astrocytoma increasing the levels of PTEN protein decreased, on the other hand the levels of p53, Ki-67 increased. There was a negative correlation between PTEN expression and grade of astrocytoma while there was a positive correlation between p53, Ki-67 expression and grade of astrocytoma by using the Spearman Correlation test to analyse the data. The incidence of Ki-67 positive expression was 24.3 % in 37 cases exhibiting PTEN positive staining, whereas the incidence of Ki-67 positive expression was 77.4 % in 31 cases exhibiting PTEN negative staining. In statistics, there was an inverse correlation between PTEN and Ki-67 expression. Conclusion There is an inverse correlation between histopathological grades of astrocytoma and PTEN expression. A positive correlation is found between p53, Ki-67 expression and histopathological grades of astrocytoma. PTEN can inhibit tumor cell proliferation in astrocytoma.