Hepatic echinococcosis(HE)is a zoonosis seriously affecting the population in west China.Computed tomography(CT),magnetic resonance angiography,ultrasound angiography can be used for detection of HE with the advantages of multiple angles and high definition.CT perfusion imaging,magnetic resonance perfusion imaging,diffusion weighted imaging and magnetic resonance spectrum may provide molecular imaging to visualize HE in vitro.Total cystectomy is a radical method for the treatment of hepatic cystic echinococcosis (HCE),but has the drawbacks of HE recurrence and bile leakage;subradical cystectomy not only eliminate residual cavity of HAE,but also effectively avoids the risks which might be caused by total cystectomy.Radical hepatectomy is the first choice for the treatment of hepatic alveolar echinococcosis(HAE),while for patients with end-stage HCE,liver transplantation is the final choice of treatment.

Hearing ; Humans ; Neuroma, Acoustic ; surgery ; Neurosurgical Procedures ; methods

Hepatic alveolar echinococcosis (HAE)is a zoonotic parasitic disease that seriously threatens the population in western China and compromises patients′quality of life.With the continuous improvement in radical resection rate in recent years,late-stage HAE pa-tients that were incurable in the past now have the opportunity for radical resection.However,patients who are not suitable candidates for radical resection still suffer from various complications and poor quality of life.Therefore,HAE is still considered a refractory and complex disease.The simple empirical treatment model provided by traditional professional discussion is unable to satisfy the treatment of advanced refractory HAE as it is unable to integrate specialized,standardized clinical skills for diagnosis and treatment.Multidisciplinary individual-ized treatment (MDT)organically integrates the advantages of the available treatment into a reasonable individualized comprehensive treat-ment regimen.This review summarizes the advances in MDT for HAE as the best option to increase long-term survival,and suggests MDT as the first-line treatment for late-stage refractory hepatic alveolar echinococcosis.

The Bland-Altman method has been widely used for consistency evaluation in the field of medicine .However, fre-quent errors in the application of the method seriously affect the quality of researches .This review focuses on the studies of the Bland-Altman method , the status quo and common problems in its application , and standards for related reports .

Recently the lysine succinylation was discovered in vivo, and it was demonstrated to be widely involved in cell dif-ferentiation, cell metabolism and other important physiological activities.Lysine succinylation has become the forefront of life science research.Scientists have provided a lot of evidences that proteins in prokaryotes and eukaryotes are widely succinylated, without which the central metabolism and intermediary metabolism of many metabolic enzymes are disrupted.To better understand the importance of Succinylation in vivo, protein-succinyl modification of the current research and the latest developments are reviewed, which summarize succinylated protein lysine sites in the center of important physiological metabolic pathways, diseases and other pathological conditions.

Objective To review the management of distal common bile duct stenosis found on Ttube cholangiography.Methods This is a retrospective study on 63 patients who were found to have a distal common bile duct stenosis on T-tube cholangiography after cholecystectomy and bile duct exploration.In 30 patients,the T tube was removed.In 14 patients,the T tube was kept draining for 6 month.Seven patients developed biliary obstructive symptoms after the T-tube was spigotted,but in 3 of these patients,the T-tube could finally be removed by prolonging the spigotted time.In the remaining 4 patients,another operation was required 3 month after the first operation.In 13 patients the T tube was taken out after 6 months following balloon dilation.Results In 47 patients in whom the Ttube could be spigotted,41 patients (87.23％) did not develop any biliary obstructive symptoms on follow up for 2 6 years,while 6 patients developed biliary obstructive symptoms (12.77％).In 13 patients who received halloon dilation,7 developed biliary obstructive symptorns (53.85％).Conclusions In patients after common bile duct exploration,if distal common bile duct stenosis was found on T-tube cholangiography,the T-lube could he spigotted and the T-tube could be taken out if no obstructive symptoms developed.

Objective To review our experience in the diagnosis and surgical management of aberrant right posterior hepatic bile duct injury.Methods Twenty eight patients with aberrant right posterior hepatic bile duct injury treated at the First Affiliated Hospital of Xinjiang Medical University between January 2002 to December 2011 were studied retrospectively.According to the injury type and the time of diagnosis,these patients were divided into three groups.The first group comprised of 10 patients in whom the injury was recognized and repaired at the time of the original surgery.The second group consisted of 10 patients in whom the injured aberrant right posterior hepatic bile duct was diagnosed and treated after operation.The third group comprised of 8 patients who developed an external bile fistula after the aberrant right posterior hepatic bile duct injury.The short and long term complications after surgical repair in the three groups were compared.Results In the first group,1 patient developed an intra-abdominal fluid collection.There was no bile stricture patients in first group.In the second group,1 patient developed bile fistula,2 patients intra-abdominal fluid collections,1 patient wound infection,and 1 patient bile duct stricture.In the third group,2 patients developed bile fistula,1 patient intestinal obstruction,2 patients wound infection,1 patient intra-abdominal hemorrhage,2 patients bile duct stricture and 1 patient an incisional hernia on follow-up.Conclusions Finding and repairing an aberrant right posterior hepatic bile duct injury at the original operation is the best treatment.According to the type and time of diagnosis,different surgical repair methods can be used for the aberrant right posterior hepatic bile duct injury.

Adolescent ; Adult ; Blast Injuries ; complications ; Deafness ; etiology ; therapy ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Young Adult

AIM: To investigate the effect of platelet-derived growth factor (PDGF) on ?_3 integrin gene expression and the role of ?_3 integrin on adhesion, migration and proliferation of vascular smooth muscle cells (VSMC) induced by PDGF. METHODS: ?_3 integrin gene expression was detected by RT-PCR. After ?_3 integrin extracellular domain was blocked, VSMC adhesion, migration and proliferation were measured by adhesion assay, a wound-culture model and [~3H]-TdR incorporation, respectively. RESULTS: After the interaction between ?_3 integrin and extracellular matrix was blocked, VSMC proliferation was inhibited in some degree and the rate of [~3H]-TdR incorporation into VSMC decreased 39%. The cell adhesion and migration were significantly inhibited when 10 mg/L anti-?_3 integrin antibody was added (P

0.05). The mean operation time of the LAVH group was significantly shorter than that of the TLH group [(95.6?18.2) minutes vs (112.9?24.5) minutes, t=-4.883, P=0.000]; whereas, the blood loss in the LAVH group was significantly more than the TLH group [(73.8?50.8) ml vs (49.8?26.9) ml, t=2.926, P=0.004]. Conclusions Laparoscopic hysterectomy is safe and feasible. Both LAVH and TLH have advantages. TLH is more suitable to experienced doctors.