1.Clinical Observation on the Effect of Psychological Intervention Combined with Fresh Motherwort Capsule in the Treatment of Postpartum Lochiorrhea and Waist Pain
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):80-82
Objective To investigate the clinical effect of psychological intervention combined with fresh motherwort capsule in the treatment of postpartum lochiorrhea and waist pain. Methods 86 cases of postpartum lochiorrhea and waist pain patients admitted to our hospital from January 2016 to December 2016 were selected. The patients were divided into observation group and control group according to the random number table method, 43 cases in each group. The control group was treated with routine nursing combined with the treatment of uterine stopping granule, while the observation group was treated with psychological intervention combined with the fresh motherwort capsule. After 1 month of intervention, the postoperative morbidities (the amount of lochia, the duration of lochia, the blood, and the bloody) and the abdominal pain and the condition of anxiety and depression before and after treatment were statistically compared between the two groups. Results Two groups of lochia status and waist pain were compared before treatment, and there was no statistically significant difference; After 1 month of intervention, the postoperative morbidities (the amount of lochia, the duration of lochia, the blood, the bloody) and the scores of abdominal pain in the observation were lower than those in the control group. And there was statistically significant difference; After 1 month's intervention, the anxiety and depression scores of the observation group were lower than that of the control group; the difference was statistically significant (P<0.05). Conclusion The treatment of psychological intervention combined with fresh motherwort capsules can reduce postpartum lochia amount of bleeding, shorten the duration of lochia, reduce abdominal pain, improve patient's psychological state, and promote postpartum recovery.
2.Prevalence and risk factors of diabetic retinopathy in type 2 diabetic inpatients
International Eye Science 2015;(2):337-339
AlM: To investigate the risk factors of diabetic retinopathy ( DR) in type 2 diabetes patients.METHODS:A total of 380 cases of type 2 diabetes were selected from January 2014 to June 2014, divided into DR group (126 cases) and non-diabetic retinopathy ( NDR) as control group (254 cases), all patients were underwent medical history, physical examinations, laboratory and assistance examinations. The prevalence and single factor and multiple factors of DR were analysed by the logistic regression model.RESULTS: The univariate logistic regression analysis showed that DR was associated with diabetes duration, systolic blood pressure, triglyceride, total cholesterol, low - density lipoprotein, urine protein, intraocular pressure, carotid intima - media thickness, peripheral neuropathy disease was the related risk factors for DR. ln multiple logistic regression analysis, only duration was the related risk factors for DR.CONCLUSlON:The occurrence of DR is the outcome of combined action of multiple factors, duration is an independent risk factor for occurrence of DR.
3.Applications of 18F-Fluorodexyglucose Positron Emission Tomography on the Diagnosis and Treatment of Carcinoma of Large Intestine
Chinese Journal of Bases and Clinics in General Surgery 2003;0(02):-
Objective To introduce the current study on 18F-fluorodexyglucose positron emission tomography (18F-FDG PET) scanning in diagnosis and treatment of carcinoma of large intestine.Methods The literatures about 18F-FDG PET scanning in diagnosis and treatment of carcinoma of large intestine in recent years were reviewed.Results 18F-FDG PET scanning is superior to CT and MRI in identificating carcinoma of large intestine recurrence, metastasis in the early stage after operation and staging carcinoma of large intestine.Conclusion 18F-FDG PET scanning may be one of the accessory examinations in carcinoma of large intestine and may be helpful for the choice of treatment.
4.Analysis of the relationship between serum HBV-DNA And hepatic fibrosis
International Journal of Laboratory Medicine 2015;(3):326-327,330
Objective To analyze the relationship between serum HBV-DNA and hepatic fibrosis in patients with hepatitis B. Methods Serum HBV-DNA load and hepatic fibrosis hyaluronic acid (HA),Ⅲ procollagen N terminal peptide(PⅢNP),laminin (LN),Ⅳ collagen(Ⅳ-C)of 154 cases were detected by real-time fluorescence quantitative PCR and chemiluminescence method. Statistical analysis of the correlation between HBV-DNA load and hepatic fibrosis indicator was performed.Results The data of HBV-DNA load after taking lg value was 5.49±1.39;The serum concentration of hepatic fibrosis HA was (166.95±148.20)ng/mL,PⅢNP was (12.14±7.37)ng/mL,Ⅳ-C was (65.29±45.48)ng/mL,LN was (59.52±35.67)ng/mL.The difference between experimental group and control group in hepatic fibrosis was significant(P <0.05).Serum HBV-DNA only correlated with LN(r=0.284,P =0.015).Conclusion There is no significant correlation between serum HBV-DNA and hepatic fibrosis in hepatitis B pa-tients.Anti-fibrosis treatment should also be strengthened for hepatitis B patients in the course of antiviral treatment.
5.The effect evaluation of bronchodilation agents in the treatment of childrens with airway hyperresponsive dis-ease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(z1):1-3
Objective To objectively evaluated of the efficacy of bronchodilation agent by using pulmonary function .Methods 104 childrens with airway hyperresponsive diseases who saw doctor at the Guangdong Women and Children′s Hospital,aged 0~6 years.They were classified into three groups:salbutamol group(n=36);ipratropium bromide group(n=32) and two drugs group(n =36).Each group received salbutamol or ipratropium bromide or both.Then tidal breathing flow-volume loop and parameters were obtained before and after aerosol inhalation to evalu-ate the effects of drugs .Results There were significant improvement in each group after the inhalation of bronchodi -lators.Conclusion The two drugs of Salbutamol and ipratropium bromide can be used as the selective drugs of bron -chodilation .
7.Comparison between Lysimachiae Herba and Desmodii Styracifolii Herba in pharmacological activities.
Ying XIONG ; Jun-wen WANG ; Jun DENG
China Journal of Chinese Materia Medica 2015;40(11):2106-2111
Lysimachiae Herba and Desmodii Styracifolii Herba are common traditional Chinese medicines for treating lithiasis. Both of them have efficacies of clearing heat, diuresis and eliminating calculi. However, there are some differences in their clinic applications. The former is mainly used to treat hepatolithiasis, gallstones, jaundice, stranguria and gout; Whereas the latter is mainly used to treat urinary calculus. In this paper, the pharmacological effects of Lysimachiae Herba and Desmodii Styracifolii Herba on removing calculus, choleresis, anti-inflammation and oxidation resistance were compared and analyzed based on document retrieval. In conclusion, both of them show the preventive and therapeutic effects on kidney stones and gallstones. Particularly, Desmodii Styracifolii Herba has a better effect in treating the kidney stones, while Lysimachiae Herba has a better effect in treating cholesterol gallstones.
Drugs, Chinese Herbal
;
pharmacology
;
therapeutic use
;
Fabaceae
;
Gallstones
;
drug therapy
;
Humans
;
Kidney Calculi
;
drug therapy
;
Medicine, Chinese Traditional
;
Phytotherapy
;
Primulaceae
8.Clinical observation on treatment of infantile repeated respiratory infection by combined use of heluo oral liquid and Astragalus.
Ying DENG ; Yue FAN ; Wen-hui HUANG
Chinese Journal of Integrated Traditional and Western Medicine 2004;24(6):552-553
Adjuvants, Immunologic
;
therapeutic use
;
Astragalus Plant
;
Child
;
Child, Preschool
;
Drug Therapy, Combination
;
Drugs, Chinese Herbal
;
therapeutic use
;
Female
;
Humans
;
Infant
;
Male
;
Nucleic Acids
;
therapeutic use
;
Phytotherapy
;
Pneumonia
;
drug therapy
;
immunology
;
Recurrence
;
Respiratory Tract Infections
;
drug therapy
;
immunology
;
Tyrosine
;
therapeutic use
9.Establishment and Application of a Real-Time Quantitative PCR Assay for Detection of Campylobacter Jejuni in Human Feces
Yunpeng CHEN ; Wen LIN ; Jianping DENG
Journal of Modern Laboratory Medicine 2014;(5):85-88
Objective To establish a real-time quantitative PCR assay for the identification of Campylobacter jejuni in fecal samples.Methods Specific primers of the PCR were designed according to the conserved sequences of Campylobacterjeju-ni,and the real-time quantitative PCR assay was established.150 cases of fecal samples were tested by both culture and PCR methods.With the culture testing results as the reference standard,the sensitivity,specificity,accuracy and repetition of the real-time quantitative PCR were validated.Kappa test was used to estimate the difference between the two detection meth-ods.Results The standard carve of the real-time quantitative PCR assay fitted the equationY=-3.51Log(X)+37.09 (R2=0.996)well.The sensitivity,specificity,and accuracy of the established method were 92.4%,95.8% and 94%,respective-ly.The theoretical detection limit of the PCR method was 102 CFU/ml,and its reproducibility was good (CV<5%).Statisti-cal analysis demonstrated that the results of the two methods were consistent,and the consistent strength was very strong (Kappa=0.88,P<0.05).Conclusion The established real-time PCR method can assay the Campylobacterjejuni in human fecal samples rapidly and accurately.
10.Study on the Quinolone Antibiotic Resistance and Its Relative Genes in Campylobacter Jejuni
Yunpeng CHEN ; Wen LIN ; Jianping DENG
Journal of Modern Laboratory Medicine 2015;(2):27-29
Objective To establish a real-time fluorescence PCR method to detect the drug resistance genes of pathogenic Campylobacter jejunum in human stool samples,and investigate the relationship between quinoloneantibiotic resistance and the related genes in Campylobacter jejuni .Methods According to the gyrA and gyrB gene sequences that related with the fluoroquinolone resistance in Campylobacter jejuni ,the primers of the PCR method was designed and synthesized.A rapid real-time fluorescence PCR method to detect the drug resistance genes in Campylobacter jejuni samples was established,and the optimum reaction system and conditions were screened through an optimized approach.The developed method was com-pared with the classical drug susceptibility assay.Results It was found in the compared results that,there were 8 inconsis-tent strains of Campylobacter jejuni ,2 of the 8 strains were drug sensitive but contented the drug resistance gene,while 6 strains were drug resistant but had no drug resistant gene.Conclusion The established method can be applied to detect the drug resistance relative genes of gyrA and gyrB in Campylobacter jejuni .There was some correlation between the drug re-sistance representation and its genotype,but this point requires further studies.