BACKGROUND: Effect of exercise training on ultrastructure of skeletal muscle is a focus of quantified cytobiology in sports medicine. OBJECTIVE: To explore the changes of transportation function of calcium ion in sarcoplasmic reticulum of muscle in the model of reduced training after endurance training. DESIGN, TIME AND SETTING: The randomized animal trial was performed at Xi'an Sports Institute from April to July 2006, and the biochemical test was performed at the Animal Experimental Center of Xi'an Jiaotong University in July 2006. MATERIALS: Thirty-nine healthy 2-month-old male SD weighing (220?20) g were selected. METHODS: Five rats were used in the preliminary experiment, and the others were randomly divided to normal control group (n=8), endurance training group (n=8) and reduced training group (n=18). The increasing training period of endurance training group and reduced training group lasted for 6 weeks, and then reduced training group was randomly divided to 3 groups according to reduced training cycle: 2, 4 and 6 weeks group. The rats did increasing endurance loading exercise on a treadmill, while reduced intensity was used in reduced training group. MAIN OUTCOME MEASURES: Enzyme coupling method and fluorescence probe technology were used to detect sarcoplasmic reticulum Ca2+-ATPase (adenosine triphosphatase) and maximum Ca2+ uptake and release of gastrocnemius muscle. RESULTS: The activity of Ca2+-ATPase in endurance training group was significantly increased compared with normal control group (P 0.05); reduced training 4 and 6 weeks groups were significantly reduced compared with endurance training group (P 0.05); while the maximum uptake and release of Ca2+ in sarcoplasmic reticulum of reduced training 4 and 6 weeks group was significantly reduced (P

BACKGROUND:The androgen response to resistance exercise is one of hot topics in sports science research. At present, the androgen responses to resistance exercise show different results. There are different androgen changing trends under different resistance exercise interventions.
OBJECTIVE:To have a deep insight into the influence of resistance exercise on the response of human body androgen, clarify research progress in androgen response to resistance exercise, and provide the basic theory for monitoring resistance training.
METHODS:Literatures and paper reports about androgen response to resistance exercise are electronical y retrieved from the American Biological Medical Literature Database PubMed from 1986 and 2013. Final y 46 literatures addressing the research progress is analyzed about androgen responses to resistance exercise were included.
RESULTS AND CONCLUSION:Studies have shown that, weight lifting (power snatch and power clean), squating, and deadlifting produced higher testosterone levels than the smal muscle groups. Under the same load, eccentric and concentric contractions produced the same hormone response. Adequate training amount and intensity may change the circulating testosterone levels. Short sports intermittent time led to a higher testosterone response than the long intermittent time. The free testosterone levels in youth group were significantly increased compared with the older group before and after exercise. Nutrition intervention affected acute testosterone responses to resistance exercise. Changes in exercise intensity and amount wil alter quiet testosterone levels, once returned to normal training, testosterone levels wil return to baseline values. Resistance exercise can increase androgen receptor content in human skeletal muscles.

Chronic obstructive pulmonary disease(COPD) is a common condition among the old,which remains a main cause of death due to its high fatality.Airway remodeling is one of its pathological features.This article reviews the pathological changes and imageological assessment of COPD airway remodeling,its correlation with microbes and its pathogenesis and therapies.

AlM: To investigate the risk factors of diabetic retinopathy ( DR) in type 2 diabetes patients.METHODS:A total of 380 cases of type 2 diabetes were selected from January 2014 to June 2014, divided into DR group (126 cases) and non-diabetic retinopathy ( NDR) as control group (254 cases), all patients were underwent medical history, physical examinations, laboratory and assistance examinations. The prevalence and single factor and multiple factors of DR were analysed by the logistic regression model.RESULTS: The univariate logistic regression analysis showed that DR was associated with diabetes duration, systolic blood pressure, triglyceride, total cholesterol, low - density lipoprotein, urine protein, intraocular pressure, carotid intima - media thickness, peripheral neuropathy disease was the related risk factors for DR. ln multiple logistic regression analysis, only duration was the related risk factors for DR.CONCLUSlON:The occurrence of DR is the outcome of combined action of multiple factors, duration is an independent risk factor for occurrence of DR.

Objective To analyze the related risk factors of pathological changes of cardiocerebral vascular in type 2 diabetes mellitus (T2DM) patients with hypertension.Methods 100 patients with T2DM were selected as the research subjects.According to the presence of hypertension,they were divided into control group (without hyper tension) and observation group (hypertension),50 cases in each group.The incidence of pathological changes of cardiocerebral vascular in the two groups was compared,and the risk factors of pathological changes of cardiocerebral vascular were analyzed.Results In the control group,the pathological changes of cardiocerebral vascular in 16 cases,the incidence rate was 32.0％.In the observation group,the pathological changes of cardiocerebral vascular in 33 cases,the incidence rate was 66.0％.The incidence rate of the observation group was significantly higher than the control group,there was statistically significant difference (x2 =10.427,P ＜ 0.05).The age,smoking,diet,exercise,fat metabolic disorders,diabetes,glycemic control,diabetic complications between the two groups had statistically significant differences (all P ＜ 0.05).Conclusion Complicated with hypertension will increase the pathological changes incidence of cardiocerebral vascular in patients with T2DM at a certain extent.The age,smoking,diet,exercise,lipid metabolic disorders,diabetes,glycemic control,diabetic complications are related risk factors to hypertension induced the pathological changes of cardiocerebral vascular in patients with T2DM.

Objective To understand the motivation of blood donation and the main influencing factors of blood donation behav-ior to formulate a targeted recruitment strategy.Methods A stratified cluster sampling method was adopted to perform the ques-tionnaire investigation on the influencing factors of blood donation without payment in 583 non-donors and 554 blood donors of Fos-han City.The analysis was performed by using the chi square test and Logistic regression analysis method.Results The character-istics of blood donation population were more males,aged 20-<30 years old,high school or secondary education,monthly income in 1 000-<3 000 Yuan;the main motivation for donating blood wasdevotion to love and social responsibility;the blood donation behavior was affected by the factors ofdevotion to love and social responsibility,give repeated donors certificate and medalfear of infectious disease and blood donation will affect healthfear of painandblood donation site traffic inconvenience and other factors.Conclusion The factors of incentive measures,barriers measures,psychological factors,blood donation services,and so on will affect the citizens to donate blood.Different recruitment strategies should be developed for different crowds.

The noradrenaline(NE) content in ovary as well as estrogen(E) and progester-one(P) levels in blood of the mature and inmature rats were determined with spec-trophotofluorometry and radioimmunoassay respectively. The ovary NE content and blood E,P levels have been found to fluctuate during estrous cycle. By using linear regression, it shows that blood P level (Y) is affected by the ovary NE content (X) in a linear manner, where Y = 0.002X-1.2(Significance test of regression coefficient, P

Objective To study the relationship between survival rate and pathogen,subtype,stage,delivered methods of 55 patients with severe hepatitis during late period of pregnancy.Methods Clinical data of 55 cases with severe hepatitis during late period of pregnancy was analyzed retrospectively.Results The incidence of hepatitis B was highest in patients with severe hepatitis during late period of pregnancy (84.5%).In subtypes,the incidence rates of chronic severe hepatitis,acute severe hepatitis and subacute severe hepatitis were 83.6%,5.5%,10.9% respectively(P

The recombinant plasmids containing IFN-?B gene fragments were constructed by ligating IFN gene fragment trimmed by Bal-31 exonclease and vector pUR222 digested by HincⅡ . In some of the recombinant plasmids ?B-IFN gene was able to be expressed under the control of lac. promoter of pUR222. Over 700 transformants were screened by cylopathogenic inhibition assay in microplate. Fifteen transformants showed antiviral activity,and one of them, pSM2317 reached 1?108 U/L.

AIM: To investigate the mechanisms of Chinese herbal medicin e formulas (Qi-ling-tang, Ba-wei-di-huang-wan and Chai-ling-tang) in the p revention and treatment of diabetes. METHODS: Wistar rats were d ivided into five groups and treated with Qi-ling-tang (the group QLT), Ba-wei -di-huang-wan (the group BWDHW), Chai-ling-tang (the group CLT), water (the group model) and control, respectively. The rats in groups QLT through model we re injected with 30 mg?kg -1 /daily streptozotocin (STZ) for five days beginning on day 8. The glucose concentration, fructosamine, insulin, total-pr otein, albumin and the percentage of W3/25 and OX8 T-cells in serum as well as the body weight of the rats were measured. Tissue sections of paraffin-embedde d pancreas of the rats were observed after staining with HE, AZAN and immunohist ochemistry. RESULTS: After STZ injection, the diabetic incidence of the rats in groups QLT, BWDHW and CLT were significantly lower than that in the group model, especially in the group BWDHW was only 21% by study day 10. A significant decrease in blood glucose concentration was found in groups BWDHW (25%) and CLT (18%) from study day 15 to 26. The percentage of W3/25 cell s in groups QLT and BWDHW was higher than that in the control group. The averag e area of islets and the area of bate cells were greater in groups QLT, BWDHW an d CLT than in the group model. CONCLUSION: Three formulas retard the development of hyperglycemia of rats induced with multiple low doses STZ by increasing the cell mediated immunofunction. The formulas Ba-wei-di-huang-w an and Chai-ling-tang can reduce hyperglycemia.