1.The recognition and practice of perioperative nutrition support therapy for patients with operable cancer
Chinese Journal of Clinical Nutrition 2012;20(2):65-68
Operable cancer patients should receive nutritional risk screening or/and nutritional assessment before surgery.Perioperative nutrition support therapy should be planned and implemented for the patients with nutritional risk or malnutrition,but not necessarily following special nutritional formula.Reducing the time of preoperative fasting,providing reasonable preoperative nutrition support,and early postoperative feeding in combination may be the preferred strategy for perioperative nutritional intervention and management.Because the disease of cancer patients is complicated and changeable,perioperative nutrition support is not only a technology,but also an “art”.The guidelines,disease information,and clinical experience should be “cleverly tailored and combined” to promote the outcome-improving effect of nutrition support therapy.
2.Characteristics of hospital infection and distribution of pathogens in patients with Chronic Hepatitis B
Clinical Medicine of China 2013;(5):524-526
Objective To analyze the situations of hospital infection among patients with Chronic Hepatitis B and explore the characteristics and risk factors.Methods Totally 315 patients with Chronic Hepatitis B were chosen and studied to analyze the infection body sites,distributions of pathogens and the risk factors which might cause reproductive tract infections.Results The analysis of 315 cases showed that the infection rate was 17.14% (54 cases),and the most infection sites was abdominal infection(37.04%).Eightyfour pathogens were detected and the gram-negative bacteria were 52 plant of most(61.9%).Hospital infections of patients with Chronic Hepatitis B were closely related to age,hospital time,using of antibiotics,clinical stage,hypoproteinemia,invasive manipulation and underlying disease.Conclusion It is effective to reduce the infections by treating early,promote the nursing mind and nutritions.Using the antibiotics reasonable and enhance the educations of psychology.
3.Effects and mechanisms of insulin postconditioning on myocardial protection in isolated rat hearts
Journal of Chongqing Medical University 2007;0(08):-
Objective:To explore the effects and mechanisms of insulin postconditioning on myocardial protection in isolated rat hearts.Methods:32 Wistar rats were randomly divided intocontrol group,ischemia/reperfusion group(I/R group),low dose insulin postconditioning group(L-POST group)and high dose insulin postconditioning group(H-POST group),with 8 rats in each group.Langendorff and neely perfusion models were steadily established,then the rat hearts were arrested by cardioplegia(St.Thomas No.2 solution,STH-2)after perfusion for 30 min.These arrested hearts were remained for 30 min at 4℃and then underwent reperfusion for 60 min.In L-POST group and H-POST group,the arrested hearts were reperfused by Krebs-Henseleit buffer solution(K-H)with insulin.The content changes of myocardial eNOS and PKC were detected by immunohistochemistry and Western blo(tWB),the AI(Apoptosis index,AI)of cardiomyocyte was detected by TUNEL.Results:Compared with control group,higher expression of eNOS and PKC and higher AI were detected in I/R group、L-POST group and H-POST group (P
4.The chinese version of the patient rated wrist evaluation (PRWE): cross-culture adaptation and reliability test
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(08):-
Objective To evaluate the test-retest reliability and internal consistency of a Chinese version ofthe PRWE in a group of patients with distal radius fracture and to compare it with the original PRWE. MethodsThe original PRWE was translated into Chinese. Test-retest reliability was obtained by repeating the PRWE to thesame subjects in one week interval and presented by intra-class correlation coefficient (ICC), internal consistencywas measured by Cronbachs coefficient alpha. Results The Chinese PRWE has good test-retest reliability and in-ternal consistency which are equivalent to the results from the English PRWE. The ICC for the Chinese PRWE rangedfrom 0. 88 to 0. 92. and Cronbach Alpha for the Chinese PRWE ranged from 0. 87 to 0. 97. Conclusion The Chi-nese version of PRWE is equivalent to the original PRWE with acceptable level of reliability and internal consistency.It is a good functional assessment tool for patients with distal radius fractures.
5.Swertiamarin of related overground and underground organ of Gentiana
Chinese Traditional Patent Medicine 1992;0(04):-
flower, changed with the blossoming period. CONCLUSION: It may be a relationship between the content and blossoming period.
6.Key advances in the clinical studies of ANCA-associated vasculitis
Journal of Medical Postgraduates 2016;29(3):323-326
Anti-neutrophil cytoplasmic antibodies( ANCA)-associated vasculitis ( AAV) has various clinical symptoms, thus various treatment schemes were used in clinics.To date, there has been no validated diagnostic criteria or treatment guideline for AAV.There are three aspects to be considered when assessing the treatment with AAV patients:staging of disease, distinction between disease activity and chronic damages, and quality of life ( QOL) .This review focuses on the latest classification of vasculitis, the rela-tion between disease stages and its severity, the importance of distinguishing active diseases from permanent damages, the therapeutic choices and the management of complications.
7.Postoperative radiation therapy in gastric cancer
China Oncology 2000;0(06):-
Radiation therapy or chemoradiation will be used much more commonly in the treatment of patients in postoperative gastric cancer . We have reviewed the indication, toxicity, radiation dose, radiation field in postradiotherapy of gastric cancer patients.
8.Expression of VEGF Eukaryotic Expression Vector in HaCaT Cells and Its Biological Effects
Chinese Journal of Dermatology 2003;0(07):-
Objective To investigate the feasibility of transient transfection of human VEGF165 gene into HaCaT cells and the effects of supernatant from transfected cell culture on pig hair follicles in vitro. Methods PIRES2-EGFP-VEGF165 was transiently transfected into HaCaT cells with lipofectamine?2000. Expression of EGFP( enhanced green fluorescence protein, EGFP) was observed by laser confocal microscopy. VEGF in the supernatant was detected by ELISA. Further,the supernatant was added to pig hair follicles cultured in vitro. The growth and morphologic changes of hair follicles were measured. Results PIRES2-EGFP?VEGF165 was successfully transfected into HaCaT cells, which confirmed by laser confocal microscopy and ELISA. Moreover, the supernatant of HaCaT cells transfected with PIRES2-EGFP-VEGF165 could accelerate the growth of pig hair follicles and prolong their anagen phase. Conclusion PIRES2-EGFP-VEGF165 could be successfully transiently transfected into HaCaT cells, and expressed VEGF could upregulate the growth of pig hair follicles in vitro.
9.Extent of lymph nodes dissection for advanced gastric cancer
International Journal of Surgery 2009;36(5):341-344
For more than a century, surgical treatment of gastric cancer is always a subject of debate, es-pecially for the extent of lymph nodes dissection for advanced gastric cancer (AGC). In this article, we re-viewed the advances on lymph node excision in AGC.
10.Research progress of dendritic cells based cancer vaccines against gastrointestinal cancers
International Journal of Surgery 2008;35(11):780-783
Gastrointestinal cancers are the most common types of malignant tumors in Human Beings.The main treatment remains surgery resection,in addition to which,adjunctive therapies are far not satisfactory for the target of which are not specific.Dendritic cells cancer vaccine is one of the most promising immunotherapy ways developed in the decades and some results have showed that the vaccines may help in the treatment of gastrointestinal cancers.Till now,there is no recognized standard in the design of the vaccine and no positive correlations between the immunologic effect and clinical prognosis are showed,but we believe that with the further research in the immunological mechanism and the use of new designed methods,dendritic cells cancer vaccines will play a greater role in the treatment of malignant tumors.