Objective To explore the risk factors of septicemia in hospitals. Methods A retrospective control study of cases was conducted, using SPSS software to conduct single factor and Iogistic regression analysis so as to screen possible risk ractors. Results Differences of 14 factors were shown to be statistically significant in the analysis of single factors. Further Iogistic regreasion analysis of the 14 factors indicate that the following are independent risk factors of septicemia in hospitals: basic diseases(OR = 5.3), tumor chemotherapy(OR=15.9), albumin＜30g/L(0R=5.9), vascular catheterization ＞ 2 days(OR= 5.2), operation time＞ 4 hours(OR= 4.9), continuous use of antibiotics(OR=1.1), and simultaneous use of more than 2 kinds of antibiotics(OR= 9.0).Conclusion Septicemia in hospitals results from the synergistic effect of a variety of factors. The possible risk factors that have been screened need to be further confirmed through perspective studies and clinical trials.

Objectives:To investigate the clinical impacts of chronic total occlusion (CTO) in acute non-ST segment elevation myocardial infarction (NSTEMI) patients underwent primary percutaneous coronary intervention (PCI).Methods:A total of 2 271 acute NSTEMI patients underwent primary PCI from China Acute Myocardial Infarction Registry were enrolled in this study and divided into the CTO group and the non-CTO group according to the angiography. The primary endpoint was in-hospital mortality and mortality during a 2-year follow-up. The secondary endpoint was major adverse cardiovascular events (MACE) including revascularization, death, re-myocardial infarction, heart failure readmission, stroke and major bleeding.Results:Thirteen-point four percent of the total acute NSTEMI patients had concurrent CTO. In-hospital mortality (3.6% vs. 1.4%, P<0.01) and 2-year mortality (9.0% vs. 5.1%, P<0.01) were significantly higher in the CTO group than those in the non-CTO group, respectively. Multiple regression analyses showed that chronic obstructive pulmonary disease ( HR 7.28, 95% CI 1.50-35.35, P=0.01) was an independent risk factor of in-hospital mortality, and advanced age ( HR 1.04, 95% CI 1.01-1.07, P<0.01), and low levels of ejection fraction ( HR 0.95, 95% CI 0.93-0.98, P<0.01) were independent risk factors of 2-year mortality. CTO ( HR1.67, 95% CI 1.10-2.54, P=0.02) was an independent risk factor of revascularization, but not a risk factor of mortality. Conclusions:Although acute NSTEMI patients concurrent with CTO had higher mortality, CTO was only an independent risk factor of revascularization, but not of mortality. Advanced age and low levels of ejection fraction were independent risk factors of long-term death among acute NSTEMI patients.