It is very difficult to operate the patients with malignant neoplasms combined with superior vena cava syndrome because of SVC has a special place.And it's prognosis is not good. Now we will use some relative articles to draw a synoptic conclusion in the indications ,surgical skills, and curative effects of this operation.

Objective To design and implement an Android -based medical chest system to realize informatized management of military medicine and equipment.Methods RFID tag was attached to the materials in the chest, and reading module with multiple antenna, Bluetooth module and responder were installed on the chest, Android-based PDA was developed to realize information communication.Results Trials proved that the system could perform auto classified management and precision locating of the materials in the chest, and could provide direction for medicine taking.Conclusion The system enhances the efficiency of the staff and ensures the accuracy and safety of medicine taking, and thus can be popularized in military hospitals.

AIM: To explore the different inhibitory effect of arsenic trioxide (As_2O_3) on hepatocarcinoma cell growth in SMMC-7721 and BEL-7402 cell lines and its mechanism. METHODS: The cell culture and trypan blue staining were used to study the inhibitory effect of arsenic trioxide on cell growth, and the glutathione (GSH) contents in hepatocarcinoma cells treated with arsenic trioxide were detected. RESULTS: Arsenic trioxide inhibited the growth of BEL-7402 cells in a time and dose-dependent manner. The inhibitory effect was significant at a lower dose of 0.50 ?mol/L for 24 h, however, to SMMC-7721 cells, a higher dose of 2.00 ?mol/L for 96 h was needed. The inhibitory rate of arsenic trioxide (0.25-2.00 ?mol/L) on BEL-7402 cell growth was higher than that on SMMC-7721 cells. The content of GSH in SMMC-7721 cells was much higher than that in BEL-7402 cells [(50.8?5.2) (?mol/g) protein and (18.7?1.4) ?mol/g protein, respectively]. CONCLUSION: There was a significant difference in inhibition of hepatocarcinoma cell growth by arsenic trioxide between BEL-7402 and SMMC-7721 cell lines, the cause of which may be due to the difference in GSH content in BEL-7402 and SMMC-7721 cells. [

The ongoing health reform features direct hosting of county-level hospitals by provincial level hospitals as an important means and effective attempt to improve comprehensive service capacity of the former.This paper introduces the“Hanchuan Model”,in which Hubei People’s Hospital has hosted Hanchuan city People’s Hospital,and analyzed the operation performance and hurdles found.Based on such studies,the authors recommend on the vertical integration of medical resources by means of hosting, and comprehensive reforms of county public hospitals.

Centering on hospital crisis communication management,the paper analyzed the relationship between hospital crises and new media environment.The new media form is studied as the basic dimension,to explore the new media′s timeliness,openness,interactivity and uncontrollability,as well as their impact on the hospital crisis management.It discussed the lack of hospital crisis communication management under the context of new media environment,and proposed how the hospitals make use of the new media,and adjust their strategies to respond to the crisis.These points prove both academic and practical for the construction of the new mechanism of China ’s hospital crisis communication management,and encourage the new media to play their social public functions.

Lung cancer has been widely known for its highest morbidity among all tumors in this world.Anti-sense neoclitide technology is a kind of widely-recognized gene therapy for its high efficiency and practical simplicity.This essay will briefly review principles of anti-sense neoclitide technology used in treatment of lung cancer and characteristics of this technology in gene therapy of lung cancer.

Objec0tive To investigate the molecular mechanism of the mal-production of IgA and IgA1 by tonsillar mononuclear cells (TMCs) in IgA nephropathy (IgAN) patients by measuring the mRNA expression of Iα-Cα germline transcript and the mRNA and protein expression of activated induced cytidine deaminase (AID) in cultured TMCs stimulated with lipopolysaccharide (LPS) or hemolytic streptococcus (HS) in IgAN patients as well as the chronic tonsilitis patients. Methods Twent-seven IgAN patients admitted into our hospital from Jan.2009 to Feb.2010 were enrolled.Twent-seven patients with chronic tonsillitis without renal disease were selected as control.Tonsillar mononuclear cells were isolated by density gradient centrifugation in lymphocyte separation medium.The amount of IgA or IgA1 secreted in the culture supernatants was determined by specific enzyme-linked immunosorbent assay (ELISA).Expressions of Iα-Cα germline transcript and AID mRNA were examined by real-time PCR.The AID protein was determined by Western blot. Results The production of IgA and IgA1 protein,especially the ratio of IgA1/IgA and the expression of AID protein in TMCs were significantly increased in IgAN group compared with chronic tonsillitis group (all P＜0.05).The IgA and IgA1 level of stimulated TMCs were obviously increased in patients with IgAN compared with control group (P＜0.05).And the expressions of Iα-Cα mRNA,AID mRNA and AID protein were up-regulated significantly in stimulated TMCs (all P＜0.05). Conclusions Both LPS and HS can induce the production of IgA and IgA1 and up-regulate the expressions of AID and Iα-Cα in TMCs of IgAN patients.Our results indicate that the TMCs are capable of producing high level of IgA and IgA1 stimulated by LPS or HS,whuch may be due to the　 incression of AID and Iα-Cα.

With the quick development and the requirements of internationalization of China's higher education,bilingual education has become a teaching task which is actively carried out in universities.Basic medical courses has strong professional and high abstractive characteristics.The bilingual education of basic medical courses have special requirements.Problems of bilingual education in basic medical courses teaching and possibly solutions were discussed to help better understanding of the bilingual teaching of basic medical courses and exert its advantages.

Objective To investigate the effects of inosine on the neuronal apoptosis and the expression of cytochrome C mRNA after focal cerebral ischemia and reperfusion in rats,and to explore the neuroprotective mechanisms of inosine. Methods SD rats model of focal ischemic reperfusion was induced by intraluminal middle cerebral artery occlusion (MCAO) with a nylon monofilament suture. Inosine (100 mg/kg) was injected intraperitoneally twice following MCAO. Apoptosis was determined by terminal deoxynucleotidy1 transferase-mediated uridine 5'-triphosphate-biotin nick end -labeling (TUNEL) staining. In situ hybridization was performed to examine the expression of cytochrome C mRNA. Results TUNEL-positive cells were observed 2 h after reperfusion and peaked at 1 d and 2 d after reperfusion in cortex and striatum respectively. Inosine reduced the number of TUNEL-positive cells at and after reperfusion 12 h. Cytochrome C mRNA expressed in cortex and striatum of ischemic hemisphere as early as at 2 h after reperfusion and reached a peak at 12 h and 1 d in cortex and striatum respectively. Inosine could diminish the expression of cytochrome C mRNA at and after reperfusion 12 h. Conclusions Inosine might play a neuroprotective role by inhibiting the neuronal apoptosis and the expression of cytochrome C mRNA which were induced by cerebral ischemia reperfusion injury.

Objective To investigate the effects of Xuebijing injectio (Chinese herb preparation) on intestinal function and inflammatory responses in severe burn patients. Method Thirty-two patients with comparable severity in burn injury were randomly divided into Xuebijing injectio treatment group (n = 16) and control group (n = 16). Patients in both groups received routine burn therapy, while those in Xuebijing treatment group additionally received Xuebijing injectio 100mL in intravenous drip twice a day for 7 days. Before the treatment and on the 3rd and the 7th day after the treatment, blood concentrations of diamine oxidase (DAO), lipopolysaccharide (LPS) ,tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) were determined in both groups. Analysis was made by SPSS 12.0 software. Results The plasma levels of DAO, LPS, TNF-α and IL-6 were decreased in both groups after the treatment. However, the plasma levels of DAO, LPS, TNF-α and IL-6 in the Xuebijing treatment group were significantly lower than those in control group on the 3rd and 7th day after the treatment (P＜ 0.05).Conclusions Xuebijing injectio could protect intestinal function, decrease the plasma level of endotoxin and lessen zhe inflammatory responses in severe burn patients.