1.Development of a Software for Automatically Generated Contours in Eclipse TPS.
Zhao XIE ; Jinyou HU ; Lian ZOU ; Weisha ZHANG ; Yuxin ZOU ; Kelin LUO ; Xiangxiang LIU ; Luxin YU
Chinese Journal of Medical Instrumentation 2015;39(3):225-227
OBJECTIVEThe automatic generation of planning targets and auxiliary contours have achieved in Eclipse TPS 11.0.
METHODSThe scripting language autohotkey was used to develop a software for automatically generated contours in Eclipse TPS. This software is named Contour Auto Margin (CAM), which is composed of operational functions of contours, script generated visualization and script file operations. RESULTS Ten cases in different cancers have separately selected, in Eclipse TPS 11.0 scripts generated by the software could not only automatically generate contours but also do contour post-processing. For different cancers, there was no difference between automatically generated contours and manually created contours.
CONCLUSIONThe CAM is a user-friendly and powerful software, and can automatically generated contours fast in Eclipse TPS 11.0. With the help of CAM, it greatly save plan preparation time and improve working efficiency of radiation therapy physicists.
Humans ; Radiotherapy Planning, Computer-Assisted ; Software
2.Clinical application in the rapid diagnosis of urinary tract infection
Xiqin ZHANG ; Caiping GONG ; Weisha WANG ; Suling LIU ; Tieying HOU
Chinese Journal of Laboratory Medicine 2019;42(5):375-380
Objective To explore the value of UF-5000 urinary sediment analyzer in assistant examination of urinary tract infections by comparing the results of bacteria and white blood cells for UF-5000 with those of routine laboratory methods.Methods A total of 1 021 clean mid-stage urine samples suspected urinary tract infection were collected from the inpatients and outpatients of the Guangdong Provincial People's Hospital from October to December 2017.All specimens were detected by UF-5000 to evaluate the repeatability,linearity,carrying contamination rate,stability and efficiency of review flag by the instrument.Urine bacterial culture and clinical diagnosis were used as reference standards to calculate the coincidence rate of bacterial test results with purified bacteria,coincidence rate with bacterial culture,and agreement rate with cultured colonies.The urinary fungal culture and clinical diagnosis were used as reference standards to calculate the coincidence rate,sensitivity and specificity of the fungal test.Based on the results of bacterial culture and clinical diagnosis,UF-5000 was used to detect the efficacy of white blood cells and bacteria for the diagnosis of UTI.The results of UF-5000 detection,the results of urinary dry chemistry analyzer UC-3500,and the results of bacterial smear microscopy were compared with the results of urinary bacterial culture to determine the sensitivity,specificity and sensitivity of each method,and the coincidence rate of with the culture method.Statistical analysis was performed using variance analysis,Wilcoxon rank sum test,coincidence rate test (Kappa test),and receiver operating characteristic curve (ROC curve).Results UF-5000 was used to detect bacteria and white blood cells,UC-3500 was used to detect neutrophil esterase and nitrite with good repeatability,which met the EP5-A requirements;the linear relationship between bacteria was very good in the range of 0-10 000/ml,R=0.999;the contamination rate of UF-5000 was 0.00% for bacteria,0.01% for white blood cells.The rate of UC-3500 was qualified;the bacteria was stable for 2 hours at room temperature and 6 hours at 4 ℃,and the white blood cells were stable for 4 hours at room temperature and 4 hours at 4 ℃.Compared with UF-1000i,the review flag rate of UF-5000 reduced about 77.8%.The coincidence rate of detection and purification of UF-5000 bacteria was 100.0%(16/16),that of Gram-negative bacteria (G-) was 94.0% (110/117),that of Gram-positive bacteria (G+) was 82.2%(37/45).The agreement rate of compared with bacterial colonies was 95.1%(216/227),and that of fungi culture was 77.1% (749/972),that of sensitivity was 81.9%(118/144),and that of specificity was 76.2%(631/828).UF-5000,UC-3500,and bacterial smear microscopy showed that the ability of bacterial infection of urinary tract was compared with the results of traditional bacterial culture.The UF-5000 urinary tract infection flag (UTI) had the highest agreement rate,reaching 84.1% (180/214).The sensitivity was 70.3% (52/74),the specificity was 91.4% (128/140);the coincidence rate of UC-3500 was 73.8% (158/214),the sensitivity was 25.7% (19/74),and the specificity was 99.3% (139/140);the consistency of bacterial smear microscopy was 66.4% (142/214),the sensitivity was 82.4% (61/74),and the specificity was 57.9% (81/140).Conclusion The total number of bacteria and white blood cell counted by UF-5000,the flag of bacterial and the UTI information,have partial clinical significance in the rapid detection of urinary tract infection.
3.Application of 3D printed personalized breast bracket in IMRT for breast cancer
Xiaoyan TANG ; Rong YE ; Fasheng HUANG ; Yuying YAN ; Weisha ZHANG ; Zuoyun HUANG ; Rui LING
Chinese Journal of Radiation Oncology 2022;31(7):633-637
Objective:By comparing the positioning errors caused by 3D printed personalized breast bracket and common headrest in intensity-modulated radiation therapy (IMRT), the fixation effect of 3D printed personalized breast bracket in IMRT was analyzed.Methods:Thirty-two breast cancer patients from January to July 2021 were randomly divided into a the 3D printed breast bracket group and common headrest group. All patients in two groups were kept in supine position, head tilted to the healthy side, the affected hand held the grip bar on the same side of the horizontal bar, the healthy hand held the opposite side of the vertical bar, and the chest and mandible were fixed with thermoplastic film. CBCT scan was performed weekly, and gray level registration was carried out according to the three registration regions of interest: breast or chest wall field, supraclavicular and inferior field, and axillary field. The positioning errors in the left and right, head and foot, abdomen and back directions were analyzed between two groups.Results:In the 3D printed breast bracket group, the positioning errors of breast or chest wall field, supraclavicular and inferior field and axillary field in the left and right, head and foot, abdomen and back directions were (1.75±1.26), (1.77±1.11) and (1.70±1.08) mm, (1.75±1.25), (1.72±1.09) and (1.70±1.05) mm,(1.86±1.34), (2.14±2.13) and (1.66±1.19) mm, respectively.In the common headrest group, the positioning errors of breast or chest wall field, supraclavicular and inferior field and axillary field in the left and right, the head and feet, the abdomen and back directions were (2.54±1.84), (2.73±3.62) and (2.18±2.45) mm, (3.25±2.02), (3.52±2.26) and (2.62±2.83) mm, (3.25±2.05), (4.44±2.90) and (3.10±3.18) mm, respectively.The positioning errors significantly differed between two groups (all P<0.05). Conclusions:The positioning error of 3D printed personalized breast bracket fixation is less than that of common headrest fixation. The positioning consistency of 3D printed personalized breast bracket in the three target areas of breast or chest wall field, supraclavicular and inferior field and axillary field is better than that of common headrest.
4.Design and Validation of Remote Radiotherapy System.
Luxin YU ; Xiangxiang LIU ; Weisha ZHANG ; Jinyou HU ; Lian ZOU
Chinese Journal of Medical Instrumentation 2018;42(6):417-420
Telemedicine technology is a means of deploying medical resources with low cost and high efficiency. A set of remote radiotherapy system based on Citrix was designed in this paper, so that the senior radiation therapists from the developed areas can provide medical services effectively for the patients in the rural areas. This paper focused on the design ideas and the detail of the technical implementation of how to design a remote radiotherapy system based on the existing equipment in the primary hospital. And the technical reliability and security of the remote radiotherapy system were verified by the scientific test method with pairwise comparison. The early practical experience shows that through the remote radiotherapy system the primary radiotherapy personnel and the radiotherapy experts from thirdgrade class-A hospital can form effective alliance in radiotherapy techniques to allow patients in rural areas to receive more professional radiation therapy.
Humans
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Information Systems
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Radiotherapy
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Reproducibility of Results
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Telemedicine