Environmental endocrine disrupting chemicals (EDC) may interfere with thyroid function by affecting the synthesis,release,transport,metabolism,and clearance of thyroid hormone as well as its receptor binding,etc.Thyroid hormones are essential for normal fctal brain development and for many aspects of normal adult physiology.This paper is to provide a brief overview of recent findings on thyroid disruptionly EDC.It would contribute to the development of new strategies against thyroid dysfuction.

Through the collection of Practice of acupuncture and moxibustion written by CHEN Jingwen, the acupuncture master in the Republic of China, the academic characteristics on acupuncture and moxibusiton were analyzed. The literature comparison method was adopted to compare the works of LUO Zhaoju, ZENG Tianzhi and LI Wenxian, etc. at the same period. It was discovered that CHEN Jingwen was the medical master who systematicly brought up the theory of acupoint properties earlier in the modern times. Classifying drugs based on acupoints was his academic feature. Additionally, the compatibility therapy of Chinese medicine was introduced to explain the essential ideas on the acupoints combination. The treatment was determined on the basis of zangxiang theory and the reinforcing and reducing therapy of acupuncture was emphasized in the determination of treatment and prescription. CHEN Jingwen's theory of acupoint property had been stressed and spread among the medical scholars in the Republic of China and he had made the beneficial exploration for the development of modern acupuncture and moxibustion therapy.
Acupuncture ; education ; history ; Acupuncture Therapy ; history ; Books ; history ; China ; History, 20th Century ; Humans ; Moxibustion ; history

Basic medical theory integrating with clinical practice is the motivation of medical development.In our country,basic medical theory research levels has been low because of mismatch between clinic practice and basic research in lots of affiliated hospitals of medical colleges.In this paper,according to analysize the basic medical research status of several affiliated hospitals of Shantou University Medical College,we think that it is key for enhancing basic research levels to strengthen building clinical research platform,standardize management of scientific research and guide medical staffs carrying out basic theory research from clinic practice.

Through collecting the economic operation information of the society-run blood purification institutionrs,the cost is divided into fixed cost,variable cost and mixed cost according to the relationship between the cost and the number of dialysis.It formulated the standard cost model of blood purification institutions,according to the county and city classification,the basic situation of the size and capacity of the organization were assumed.It mainly included standard labor costs,standard drug costs,standard health materials fees and standard professional equipment depreciation and other information,which was benefitial for industry decision-making and internal fine management.

Objective:Through the closed loop management mode,it realized the whole process of material information could be traced back,especially in the medical business level.Methods:Based on the requirement of management accounting,the integrated accounting and business information were in accordance with management accounting.Results and Conclusion:It set up different management nodes in the closed loop of the materials,such as medicine,sanitary materials and test reagents,so as to get the relevant information.The problems of the extensive management of materials could be solved to improve the efficiency of the management of hospital materials.

Patients with non-alcoholic fatty liver disease (NAFLD) have unhealthy diets, sedentary behavior and lack of physical activity. This lifestyle triggers liver disease and probably favors its progression. It is now the most common significant cause of end-stage liver disease and hepatocellular carcinoma. From the perspective of non-pharmacological intervention, lifestyle modifications including diet, exercise, and weight loss remain the most effective therapy for nonalcoholic fatty liver disease. Bariatric surgery in morbidly obese individuals who have failed to lose weight through lifestyle modifications can improve steatosis, inflammation, and fibrosis. Comprehensive treatment measures can produce synergistic effect, but long-term adherence is particularly critical.

Objective To investigate clinical effects of laparoscopic salpingotomy combined with pituitrin in the treatment of tubal pregnancy.Methods 160 children with tubal pregnancy were chosen in our hospital in the period and randomly divided into two groups including control group (80 children)with laparoscopic salpingotomy treatment and treatment group (80 children)with pituitrin adjunct treatment before operation on the basis of control group.And the operation time,intraoperative bleeding volume,postoperative body temperature,hospitalization time,the retention rate of fallopian tube,fallopian tube patency rate,persistent ectopic pregnancy rate,intrauterine pregnancy rate and fertility rate of both groups were compared.Results The operation time,intraoperative bleeding volume, postoperative body temperature and hospitalization time of the control group were separately (20.33 ±2.70)min, (52.76 ±7.42)mL,(37.52 ±0.54)℃ and (7.56 ±1.98)d;the operation time,intraoperative bleeding volume, postoperative body temperature and hospitalization time of the treatment group were separately (8.94 ±1.61)min, (16.33 ±2.15)mL,(37.46 ±0.50)℃and (5.91 ±1.42)d;the operation time,intraoperative bleeding volume and hospitalization time of the treatment group were significantly better than those of the control group (t=2.26,2.60, 2.08,all P<0.05 );there was no significant difference in postoperative body temperature between 2 groups (t=1.55,P>0.05).The retention rate of fallopian tube and fallopian tube patency rate of the control group were sepa-rately 75.00% (60/80)and 52.50%(42/80);the retention rate of fallopian tube and fallopian tube patency rate of the control group were separately 93.75% (75/80)and 81.25% (65/80);the retention rate of fallopian tube and fallopian tube patency rate of treatment group were significantly better than those of the control group (χ2 =9.71, 10.14,all P<0.05).The persistent ectopic pregnancy rate,intrauterine pregnancy rate and fertility rate of the control group were separately 17.50%(14/80),31.25%(25/80)and 37.50%(30/80);the persistent ectopic pregnancy rate,intrauterine pregnancy rate and fertility rate of the treatment group were separately 15.00% (12/80),61.25%(49/80)and 16.25% (13/80);there was no significant difference in persistent ectopic pregnancy rate between 2 groups (χ2 =1.33,P>0.05);the intrauterine pregnancy rate and fertility rate of treatment group were significant-ly better than those of the control group (χ2 =11.84,12.52,all P<0.05).Conclusion Laparoscopic salpingotomy combined with pituitrin in the treatment of tubal pregnancy can efficiently decrease operation time the amount of bleeding,shorten hospitalization time and be helpful to improve the reproductive outcome.

Objective To investigate the antibiotic resistance rate of Helicobacter pylori,and to provide reliable evidence of choosing optimal drugs for clinical therapy.Methods Overall 3304 patients were enrolled from February 2006 to March 2007 who accepted gastroscopy followed by Helicobacter pylori culture of the gastric mucosa from biopsy.The antimicrobial susceptibilities of Helicobacter pylori strains for six antibiotics including metronidazole,amoxicilin,gentamycin,levofloxacin,furazolidone,clarithromycin were observed by Kirby-Bauer disk diffusion test.Results 1171(35.4%)biopsy clinical specimens were proved to be Helicobacter pylori positive when cultured in vitro and identified by conventional assays.The metronidazole resistance rate(99.32%)of Helicobacter pylori was significantly higher than that of any of the other 5 antibiotics,and the levofloxacin resistance rate(0.51%)was the lowest.Furthermore there were no significantly change in the tendency of resistance rate for the two above antibiotics from February 2006 to March 2007.However,Helicobacter pylori was resistant to amoxicilin,gentamycin,furazolidone,clarithromycin,and the resistance rate was 61.06%、4.78%、21.35% and 39.45% respectively.Meanwhile,the resistance rates corresponding to four antibiotics were different obviously.Conclusions With the application of antibiotics for Helicobacter pylori eradication,the antibiotic resistance rate increased perceptibly.The rate of resistance to metronidazole appeared to be the highest among six antibiotics applied to clinical treatment.Drug susceptibility testing was valuable to eradicate Helicobacter pylori in clinical therapy.

The dynamic changes about vasoactive intestinal peptide (VIP), angiotension Ⅰ (AⅠ)and angiotension Ⅱ (A Ⅱ)concentrations in plasma, cerebral spinal fluid (CSF) and brain extracts were studied in the experimental high-velocity missile wound models, which were produced on both hind legs of dogs. The findings were as follows: (1) Plasma VIP, AⅠ and AⅡ concentrations started to increase from 30 rain after the wound and the elevation had been continuing at 4 h after the wound. Their highest points of post-trauma were 2,9, 11.5 and 4.9 times as much as that of pre-trauma. (2) CSF VIP elevated at 4 h after the wound, but AⅠ and AⅡ concentrations reduced tempo tarily at 1 h and 2 h after the wound respectively. (3) The changes of VIP, AⅡ concentrations in the brain extracts tented to be consistent with that of the CSF. The signifcance and machanism of these changes of VIP and AⅡ concentration remain to be clarified.

Objective To study the clinical features, laboratory index and therapy of hypoplastic myelodysplastic syndrome. Methods 8 patients with hypoplastic MDS by using the method of bone marrow smear and bone marrow biopsy were studied. T lymphocyte subsets were analyzed by flow cytometry. 8 patients were treated with personalized therapy. Results All the patients of this group had hypoplastic bone marrow with more than two parts, bone marrow hypocellularity and characteristics of ineffective hematopoiesis. The analysis of T lymphocyte subsets showed that 5 of 8 patients had abnormal CD+4/CD+8 ratios. After personalized treatment, there were 2 obvious remission cases, 3 partial remission cases, 2 progression cases and 1 inefficacy case. Conclusion Hypoplastic MDS is characterized by bone marrow hypocellularity and ineffective hematopoiesis, which showed immunological abnormalities. Personalized therapeutic strategy may prolong survival in patients with hypoplastic MDS.