1.Implementation of Embedded Patient Information Query System
Chinese Medical Equipment Journal 1989;0(03):-
Objective To design a mobile device for patient information query.Methods Linux was used as operating system,and embedded SQL was used to access the database.Data transmission was realized by socket programming.Results The correctness of data access and transmission was proved by test,and the validity of the system was also confirmed.Conclusion Embedded system technology meets the need of mobile medical care.
2.Realizing generalized registration of medical sequence image using mutual information criterion
Chenguang ZHAO ; Wufan CHEN ; Weipeng LI
Chinese Journal of Medical Physics 2001;18(1):23-26
Mutual information(MI) is a tool of measuring the statistical dependence between two random variables. MI between two images, being considered as two random fields, can be calculated to determine the degree of information redundancy between the image intensities of corresponding pixels in both images. In this paper, we utilize the MI criterion to realize the generalized registration between two neighboring slices in a medical image sequence (CT, MR et al) and consider that they match with each other if the MI between them is maximal. Experimental results confirm performance of our algorithm.
3.Comparison between Fast Track Cardiac Anesthesia and Regular Anesthesia for Pediatric Patients with Congenital Heart Disease
Rong WANG ; Weipeng WANG ; Lihuan LI
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To retrospectively compare the postoperative recovery and medical cost of pediatric patients underwent fast track cardiac anesthesia(FTCA,extubated in operating room)or regular anesthesia(extubated out of operating room).Methods From January 2005 to January 2006,108 children with congenital heart disease were operated under FTCA,108 patients who received regular anesthesia were set as a control group.The general characteristics,anesthetic method,postoperative treatments,recovery,and medical cost of the two groups were compared.Results The mean body weight of FTCA group was significantly higher than that in the control [(13.8?4.2)kg vs(10.9?3.8)kg,t=5.321,P=0.000].The patients received sevoflurane for anesthesia induction in the FTCA group were more than those in the control(58 vs 16,?2=36.260,P=0.000).The mean dosage of fentanyl used during operation in FTCA group was significantly lower than that in the control [(10.9?7.3)?g/kg vs(18.0?5.7)?g/kg,t=-7.697,P=0.000].In addition,fewer patients in FTCA group used more than one kind of sedative after the operation(7 vs 19,?2=6.296,P=0.012).95 patients in FTCA group returned to their ward without extubation-related complications.No significant difference in length of hospital stay was found between the two groups,however,the medical cost of FTCA group was significantly lower than that in the control(P
4.LIS design and research of security based on web technology
Xiaolin ZHU ; Weipeng LI ; Yang CAO
Chinese Medical Equipment Journal 1993;0(06):-
Functional requirement of LIS analyzed, this paper discusses the application of web technology to it. The choice of application server and security control and management are emphasized on, and then corresponding solutions are provided.
5.A unification scheme of medical treatment information network based on HL7 Engine
Bo LU ; Weipeng LI ; Xiaoyan CHEN
Chinese Medical Equipment Journal 1989;0(02):-
The development of HIS and the isolation of all the HISs are mentioned in this paper. It's suggested that HL7 be used to unify the health information. The inosculation of Laboratory Information System (LIS) and Hospital Information System (HIS) is taken as an example to introduce a unification scheme of medical treatment information network based on Health Level Seven (HL7) Engine.
6.Application of classification, clustering-based data mining technology to CLIS
Kai SU ; Weipeng LI ; Lin YANG
Chinese Medical Equipment Journal 1993;0(06):-
This paper expatiates the application of classification, clustering-based data mining technology to Clinical Laboratory Information System (CLIS) with the introduction of the concepts of CLIS and data mining.
7.HL7 message processing technology based on XML
Bo LU ; Weipeng LI ; Qi WANG
Chinese Medical Equipment Journal 2003;0(12):-
Information integration of heterogeneous systems needs implementing to meet the communication requirements of all subsystems of Hospital Information System (HIS). The solution is to introduce Health Level Seven (HL7), an international medical information exchange standard. With extensible Markup Language (XML) as the message-encoding manner, HL7 version 3 follows the object-oriented methodology. Based on the message system of HL7 version 3, this paper introduces an XML-based message processing technology and then testifies its feasibility.
8.Anesthesia for video-assisted thoracoscopic coronary artery bypass surgery
Weipeng WANG ; Lihuan LI ; Mingzheng LIU
Chinese Journal of Minimally Invasive Surgery 2001;0(04):-
Ojective To study the anesthesia technique for video-assisted thoracoscopic coronary artery bypass surgery (VATCABS). Methods The anesthesia of 14 VATCABS were reviewed retrospectively. Results The average dose of Fentanyl was (13.3?7 3)?g/kg Six (42.9%) of 14 cases were extubated at the operating room, while other 8 cases (57.9%) were extubated (4.71?2.21) hours after operation. The time of ICU stay was (45.2?35.5) hours. No anesthesia related complications were found perioperatively. Conclusions "Fast track" anesthesia technique is suitable for VATCABS.
9.Effect of gender and treatment strategy on remote ischemic preconditioning-induced reduction of myocardial damage in patients undergoing cardiac surgery: a meta analysis
Chenghui ZHOU ; Yuntai YAO ; Huatong LI ; Weipeng WANG ; Lihuan LI
Chinese Journal of Anesthesiology 2013;33(6):657-660
Objective To evaluate the effect of gender and treatment strategy on remote ischemic preconditioning (RIPC)-induced reduction of myocardial damage in patients undergoing cardiac surgery.Methods We systematically searched the literature in PubMed,EMBase,and Cochrane Library (from Feb 1990 to Feb 2012) using the related keywords.Randomized control trials (RCTs) published in English with report on postoperative biomarkers of myocardial damage concerning RIPC-induced myocardial protection in adult patients undergoing cardiac surgery were included.Standardized mean difference (SMD) was calculated.Publication bias and sensitivity analysis were used to evaluate the reliability of overall enzymatic estimate.Meta-regression analysis was performed to explore the potential sources of significant heterogeneity among results of studies.Data were analyzed using Stata 12.0.Results Thirteen RCTs involving 985 patients were included in our study.Compared with controls,RIPC significantly reduced postoperative serum levels of biomarkers of myocardial damage with significant heterogeneity (SMD=-0.539; 95%CI:-0.926to-0.152; P<0.05; I2 =88.7%,P<0.01).No evidence of obvious publication bias was observed (P =0.083,Begg' s test; P =0.077,Egger' s test).Sensitivity analysis showed that each individual study produced no effect on the direction and magnitude of the overall effect size (P < 0.05).Meta-regression analysis revealed that male (%) (coefficient =0.02 ; 95 % CI:-0.002-0.042 ; P =0.070 ; adjusted R2 =19.61%) and total ischemic time (min) (coefficient=-0.08; 95%CI:-0.154-0.002; P =0.055; adjusted R2 =19.47%) were the two major influential factors.Conclusion Gender affects RIPC-induced reduction of myocardial damage after cardiac surgery in patients,RIPC-induced reduction of myocardial damage infemale patients is superior to that in male patients and a better efficacy can be achieved by prolonging the single ischemic time or by increasing the ischemic cycles.
10.Changes of expression of angiogenic factor mRNA in the spinal cord of rat models of protruded intervertebral disc and the effects of electroacupuncture
Weipeng WU ; Wei LI ; Peng CHENG ; Daixun JIANG ; Wu CHEN
Acta Laboratorium Animalis Scientia Sinica 2015;(3):261-266
Objective The purpose of this study was to determine the changes of expression of angiogenic factor mRNA in the spinal cord of rats with protruded intervertebral disc and the effects of electroacupuncture , and to analyze the role of electroacupuncture in the spinal microvascular angiogenesis .Method Eighteen healthy male Sprague-Dawley rats were divided randomly into 3 groups:the electroacupuncture group , model group and sham-operated group .The protruded intervertebral disc models were generated by the left lateral and ventral spinal cord compression at T 13 using a self-made silicon sheet.Only the rats in the first group were treated by electroacupuncture once a day for consecutive 7 days.Spinal cord tissue samples were taken from the compression site at 7 days after operation .The mRNA levels of Ang-1, Tie-1, Ang-2, Tie-2, VEGF, Flt-1, caspase-3 and Tsp-1 were determined by RT-PCR, and the pathological changes of the spinal cord was examined using HE staining .Results The rats in the electroacupuncture treated group showed significantly im-proved hind leg function , a relatively complete spinal cord structure , and a clear boundary between grey and white matters . The expression levels of Ang-1, Ang-2, Tie-1, Tie-2, capase-3 and Tsp-1 in the spinal cord tissues of the model group were significantly higher than those of sham-operated group ( P<0.01 ) , but the levels of VEGF and Flt-1 between those two groups showed no significant difference (P>0.05).The expression levels of Ang-2, Tie-1, Tie-2, caspase-3 and Tsp-1 of the electroacupuncture group were significantly lower than those in the model group (P<0.01), while the expression levels of Ang-1, VEGF and Flt-1 were not significantly different between the two groups (P>0.05).All the indexes be-tween electroacupuncture and sham-operated groups showed no significant difference ( P>0.05 ) .Conclusions Our re-sults demonstrate that mRNA expression of relevant angiogenic factors were abnormal after spinal cord compression , while electroacupuncture can down-regulate the expression of Ang-2, Tie-2,Tsp-1 and caspase-3, and modulate the promoting and inhibiting factors of angiogenesis to return towards normal , therefore , to create beneficial conditions for the repair of spinal cord injuries .