Objective:To measure the voice samples of the normal aged in order to systemically study the fea-tures of the voice changes. Method :To collect and analyze 146 voice samples of the normal aged with sonogram.Result:The fundamental frequency of the voice of the aged decreases and rises in the male more than 80 yearsolder. The low frequency harmonics are regulation and the intensity is strong in the formant of the aged. Thedifference reduces in voice between male and female. The harmonics to noise ratio tends downwards and the am-plitude perturbation quotient tends upwards along with the growth of age in the aged male. The changes of the above-mentioned parameters are not significant in the aged female. Conclusion:The voice changes are normalphysiological ones in the normal aged. The changes of the parameters are used to evaluate normal aged voice andabnormal one. The changes show that the function in the aged phonation tends to decline to a certain extent andit must be protected and be trained.

Objective The research aimed at evaluating whether non-invasive endolymphatic MR imaging could be used in aged patients(≥60 years)suffering from Meniere's disease.Methods Under guidance of nasal endoscopy,a diluted gadopentetate dimeglumine injection was administrated through eustachian tube into mid-ear cavity in four patients (≥60 years old) suffered from Meniere's disease.3D-FLAIR MRI scan was performed one day after the administration.Results The administration succeeded through eustachian tube into mid-ear cavity in those four patients.A rise of fluid level on tympanic membrane while administrating a diluted gadopentetated meglumine injection was observed.Imaging of inner ear endolymphatic spaces were visible in vestibule and cochlea in imaging of patient 1.As to patient 2,in cochlea the scala tympani of the first and second turns were enhanced while scala vestibule weren't;Vestibules couldn't be recognized.In images of patient 3,the scala tympani of the three turns in cochlea were enhanced while scala vestibule weren't;Vestibules couldn't be recognized.For Patient 4,in cochlea the scala tympani of the first turn were enhanced while scala vestibule weren't,and the second turn was partially enhanced;and endolymphatic space of vestibule could be distinguished from perilymphatic space.Conclusions This technique could be adopted in investigation of Meniere's disease in elderly patients.MR imaging of endolymphatic spaces in vestibule and cochlea can be visualized,which may partially provide data for diagnosis of Meniere's disease.

Objective:To evaluate the clinical effect of posterior cervical pedicle screw fixation operation for cervical spondylotic myelopathy.Methods: From Mar 2014 to Sep 2015, 55 patients with cervical spondylotic myelopathy treated with posterior cervical pedicle screw fixation operation were involved. Cervical curvature in the cervical three dimensional CT by the Harrison’ s cervical curvature measuring method was measured, and JOA scores, NDI scores and VAS scores before and after operation and the last follow-up were evaluated. Results:A total of 55 patients with cervical spondylotic myelopathy obtained good operation effect and the cervical curvature and neural function were improved.The cervical curvature, JOA score, NDI scores, and VAS scores were significantly better than that before operation (P < 0.05) . Last follow-up results showed that there was statistical significance on JOA score, NDI score, and VAS score compared with that after operation (P<0.05), but not on cervical curvature (P>0.05) . Conclusion:The neurological function and cervical curvature of the cervical spondylotic myelopathy can be improved through posterior cervical pedicle screw fixation operation.