1.A comparative study on the treatment of bronchiectasis between VATS and open thoracotomy
Chenxi ZHANG ; Weimiao LI ; Peilong BAO ; Qiang CHE ; Tao WANG ; Xiaofei LI ; Jinbo ZHAO
Chinese Journal of Thoracic and Cardiovascular Surgery 2018;34(2):96-99
Objective To evaluate the safety,effectivity and feasibility of Video-assisted thoracoscopic surgery(VATS) for the treatment of bronchiectasis.Methods The data of patients with bronchiectasis treated by surgery from January 2010 to September 2016 in Tangdu hospital,the Forth Military Medical University,were reviewed and analyzed retrospectively.Results There were 343 cases enrolled in this study,which were divided into Thoracotomy group(230 cases) and VATS group(113 cases,17 of them were converted into open surgery).There were 125 males and 105 females in Thoracotomy group,with the average age of(46.1 ± 14.4) years,and 45 males and 68 females in VATS group with the average age of(45.8 ± 13.4) years.Four patients died during the perioperative period and all of them were from Thoracotomy group.Compared with the Thoractomy group,the blood loss [(292.1 ± 301.7) ml vs(475.7 ± 525.4) ml,P =0.001],length of hospitalization [(6.4 ± 2.4) dvs.(9.1 ±6.6)d,P<0.001],drainage time[(6.4 ±2.4)d vs.(9.1 ±6.6)d,P <0.001] were significantly lower in VATS group,but no difference in operation time.The cost in VATS group was higher [(4.5 ± 1.3) ten-thousand yuan vs (3.9 ± 1.8) ten-thousand yuan,P =0.001].For patients without comorbidities,the incidence of postoperative complications was lower in VATS group compared with that in Thoractomy group (P =0.003).There was no significant difference between two groups for patients with comorbidities (P =0.274),but there was a trend of declining in VATS group.Conclusion VATS is safe,effective and feasible to treat bronchiectasis,and should be a priority.
2.Effect of delayed umbilical cord clamping on blood glucose of full-term neonates in pregnancy with gestational diabetes mellitus
Weimiao SHI ; Jinxin HOU ; Wenxuan ZHANG
Chinese Journal of Modern Nursing 2017;23(17):2286-2288
Objective To explore the effect of delayed umbilical cord clamping on blood glucose of full-term natural neonates in pregnancy with gestational diabetes mellitus (GDM).Methods A total of 60 full-term pregnancy puerpera with GDM and spontaneous labor from a class Ⅲ grade A special hospital were selected with the convenient sampling method between August 2016 to September 2016. They were divided into control group (n=30, umbilical cord clamping immediately after delivery, conventional processing umbilical cord) and observation group (n=30, umbilical cord clamping 2 minutes after delivery, if the umbilical cord pulse stopped within 2 minutes, than the umbilical cord should be clamped immediately, conventional processing umbilical cord) using random number table. The change of blood glucose was compared two hours after birth. Results The blood glucose of neonate in the observation group was (4.27±0.85) mmol/L two hours after birth which was higher than that in control group (3.08±0.74) mmol/L with a significant difference (t=5.778,P<0.01). Conclusions The delayed umbilical cord clamping has a preventive effect on hypoglycemia two hours after birth in full-term natural neonates in pregnancy with GDM.
3.Pharmaceutical care for a patient with diabetes complicated with suspected hyperlipidemia induced by immuno‐ suppressive agents after liver transplantation
Weimiao LI ; Rongjing SONG ; Chunyan ZHANG ; Lin HUANG ; Xiaohong ZHANG
China Pharmacy 2024;35(18):2310-2314
OBJECTIVE To provide a reference for clinically rational drug use and pharmaceutical care for patients with diabetes complicated with hyperlipidemia induced by immunosuppressive agents after liver transplantation. METHODS Clinical pharmacists participated in the treatment of a patient with diabetes complicated with suspected hyperlipidemia induced by immunosuppressive agents after liver transplantation. Due to the poor glucose control of the patient, the clinical pharmacists assisted the doctor in adjusting the glycemic control plan: subcutaneous injection of 18, 12 and 16 units of Insulin lispro injection before meals, and subcutaneous injection of 16 units of Insulin glargine injection before bedtime. Due to the occurrence of hyperlipidemia in the patient, clinical pharmacists clarified the possible cause of abnormal blood lipid elevation was using immunosuppressants by reviewing the timeline of dose adjustment of immunosuppressive agents and changes in blood lipid levels based on relevant guidelines. Clinical pharmacists suggested using Rosuvastatin calcium tablets 5 mg, qd for lipid-lowering treatment, reducing the dosage of Mycophenolate mofetil capsules and Tacrolimus capsules to 500 mg, bid and 2 mg, bid, respectively. Medication education and pharmaceutical care were also carried out. RESULTS The doctor adopted the advice of the clinical pharmacists. After treatment, the levels of blood glucose and blood lipid in the patient improved, and he was allowed to be discharged with medication. CONCLUSIONS Clinical pharmacists provide pharmaceutical services such as recommending the addition of statins, adjusting the dosage of immunosuppressive agents, and conducting pharmaceutical care to optimize individualized medication plans for patients and ensure the safety and effectiveness of medication.
4.A qualitative study of perception of risk of relapse in patients with schizophrenia
Hong YU ; Yuqiu ZHOU ; Yujing SUN ; Guohua LI ; Dongyu HOU ; Mengnan QIN ; Jiaxin REN ; Weimiao ZHANG
Chinese Mental Health Journal 2024;38(5):388-393
Objective:To elucidate the primary elements pertaining to the perception of relapse risk and to in-vestigate the characteristics and alterations of perception of the risk of recurrence in patients with schizophrenia.Methods:By using the method of phenomenological study,semi-structured in-depth interviews were conducted among schizophrenic patients with first onset,first recurrence and multiple recurrences.Twenty-three 23 outpatient and inpatient cases that met the criteria of the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5)were included,and all patients had PANSS scores below 60.The interview data were collated and analyzed according to Colaizzi analysis.Results:The perception of recurrence risk in patients with schizophrenia en-compassed 4 major themes and 11 sub-themes,namely susceptibility(limited overall understanding,transition from optimism to objectivity),detection of early warning symptoms(dynamic escalation,assistance from family mem-bers in identification),understanding risk factors(lack of understanding,the relationship between psychosocial fac-tors and relapse,dynamic understanding of medication-relapse relationship),and apprehension of the consequences of recurrence(care burden and financial constraints,impaired social functioning and maladjustment,impact on pub-lic safety,personal health risks).Conclusion:The content of risk perception of recurrence in patients with schizo-phrenia is relatively substantial.The overall level of risk perception of recurrence in patients with schizophrenia is low.