Objective To observe the effects of Mahuang ( Herba Ephedra ) and Wuweizi ( Fructus Schisandrae) combined with dexamethasone ( DXM) on expression of angiogenic factors and inhibitors in rats with idiopathic pulmonary fibrosis ( IPF) .Methods Wistar male rats of SPF level ( n=106 ) were divided randomly into sham operation group , model group, Mahuang group, Wuweizi group, Mahuang+DXM group , Wuweizi+DXM group and DXM group .The model of IPF was established by using instilla-tion of bleomycin (7 mg/kg) except for the sham operation group .Each group was administered intra-gastrically of corresponding drug .All rats were sacrificed on the 7th and 28th day via abdominal aorta blood-letting, and the pathological changes of lung tissue were evaluated with HE staining and the expres -sion of hypoxia-inducible factors 1α( HIF-1α) , platelet derived growth factor ( PDGF) , pigment epitheli-um-derived factor ( PEDF) and endostatin in rat serum were also measured with ELISA .Results Com-pared with the sham operation group , the expression of HIF-1α,PDGF, PEDF and endostatin in model group significantly increased (P<0.01);the HIF-1αcontent on the 28th day was higher than that on the 7th day, and the PEDF and endostatin content were lower than that on the 7th day.The expression of HIF-1αand PDGF significantly decreased in Mahuang group and Wuweizi group compared with the model group, and the expression of PEDF and endostatin increased (P<0.05).Compared with Mahuang group on the 28th day,the expression of HIF-1αand PDGF on the 7th day increased markedly, but the expres-sion of PEDF and endostatin on the 28th day was lower than those on the 7th day.In the Wuweizi group the changes in the expression of HIF-1α,PDGF, PEDF and endostatin were opposite to Mahuang group.The expression of HIF-1αand PDGF significantly decreased in Mahuang+DXM group and Wuweizi+DXM group compared with the model group ( P<0 .05 ) , and the expression of PEDF and endostatin increased . In Wuweizi+DXM group the HIF-1αcontent was significantly higher than those in DXM group while the PEDF content was significantly lower ( P<0.05 ) .Conclusion Regulatory factors on angiogenesis lose their balance in rats with IPF .Mahuang and Wuweizi could achieve inhibition of the expression of HIF-1αand PDGF, and selectively promote the expression of PEDF and endostatin .When combined with DXM, the selectivity might be weakened in different pathological stages .

ABSTRACT:Objective To summarize the perioperative nursing methods for benign prostatic hyperplasia(BPH)patients undergoing photoselective vaporization.Methods 245 BPH patients applying photoselective vaporization were included in the research,and nursing plan before opera-tion was made,psychological nursing was given to the patients,changes of diseases after operation was observed,and complications were prevented.Results All of the surgeries were successful,and no patients had severe complications.All patients were discharged in 2~3 days after operation. Conclusion Good perioperative nursing is important in recovery of patients,and we should em-phasize on physical and psychological status of patient before operation,vital signs and oxygen satu-ration and the color of bladder washing to ensure the success of operation and earlier rehabilitation.

Small package of Chinese medicine decoction pieces (hereinafter “small package of TCM”) has its unique advantage.After searching the literature in CNKI,Wanfang,VIP database,the papers linked to small package of TCM were analyzed from its aspect of history,pros and cons,package select-ed,dispensing procedure.Then a“ten Chinese characters pithy formula”directed at the process of small package of TCM dispensing was summarized as “examine(Chinese:审),display (Chinese:摆),watch (Chinese:看),check (Chinese:对),take (Chinese:拿),weigh (Chinese:掂),assign (Chinese:分),verify (Chinese:核),pack (Chinese:包),dispense (Chinese:发)”,which was easy to remem-ber,to understand and to operate,contributing to improving the quality of clinical dispensing and stand-ardizing the skill of TCM dispensing.

ABSTRACT:Objective To summarize the perioperative nursing methods for benign prostatic hyperplasia(BPH)patients undergoing photoselective vaporization.Methods 245 BPH patients applying photoselective vaporization were included in the research,and nursing plan before opera-tion was made,psychological nursing was given to the patients,changes of diseases after operation was observed,and complications were prevented.Results All of the surgeries were successful,and no patients had severe complications.All patients were discharged in 2~3 days after operation. Conclusion Good perioperative nursing is important in recovery of patients,and we should em-phasize on physical and psychological status of patient before operation,vital signs and oxygen satu-ration and the color of bladder washing to ensure the success of operation and earlier rehabilitation.