150 g/L, the dose of EPO was decreased by half. The control group consisted of 20 patients given Leucogenum, the dose was 20 mg every time, 3 times per day. Results: From the fourth week after therapy, the Hb, HCT, RBC of the EPO treatment group was significantly higher than prior to treatment( P

0.05). When comparing the pH value of xylitol gum with the pH value of 0.1 kg/L sucrose solution, and comparing that with the sucrose gum, significant difference could be found between the changes of pH values at different time points (P

Objective:To investigate the effects of washed platelets at low concentration(WPLT)on the proliferation of human dental pulp cells(HDPCs).Methods:WPLT was prepared from a male venous blood,cultured HDPCs were exposed to the WPLT at 50 ml/L,100 ml/L and 200 ml/L for 0.5～24 h respectively.Cell proliferation and prostaglandin E_2 production were examined by cell counting and Prostaglandin E_2 EIA Kit-Monoclonal respectively.Cyclooxygenase-2(COX-2)mRNA expression was determined by real time RT-PCR.Results:WPLT at 50 ml/L promoted HDPC proliferation and increased COX-2 mRNA expression at 3-hour-exposure.That at 50～200 ml/L increased the production of PGE_2 dose-depandently.Indomethacin or dexamethasone reduced WPLT-induced HDPC proliferation,and this inhibitory effect was reversed by exogenous PGE_2.PGE_2 promoted HDPC proliferation at 5-100 ng/ml.Conclusion:WPLT may induce prostaglandin E_2 production,thereby promote HPDC proliferation.

Objective: To investigate the effects of Nd:YAG laser in the treatment of dentine hypersensitivity. Methods:270 teeth in 153 patients were equally divided into two groups at random. The teeth in the experimental group were treated with Nd:YAG laser at 265.5 J/cm 2 (0.75 W and 10 Hz for 2 min) for 3 times with the interval of 1 week, those in the control group were treated with Gluma desensitizer for 3 times with the interval of 2 d. Results:The effective rate of the experimental and control groups was 92.59% and 49.62% respectively (P

Objective To determine what effects diazoxide, a selective opener of mitochondrial ATP-sensitive potassium channel ( Mito-KATP ), exerts on apoptosis in hippocampal neurons caused by anoxia-reoxygenation.Methods Newborn SD rats (

Phloroglucinol is an antineoplastic effective compound from Dryopteria Crassirhizoma Nakai. In this study, mice implanted with leukemia P388 were examined under an electron microscope. It' was found that the leukemia bearing mice, which had been injected with phloroglucinol exhibited degeneration and swelling of mitochondria in the P38'8 cells. Measurement with an oxygen electrode showed that the drug treatment of P388 cells markedly lowered their oxygen consumption in comparison with the control cells .The results demonstrate that phloroglucinol inhibits respiration of tumor cells. Probably, the mitochondria of tumor cells is a target that the drug attacks.

Objective To evaluated the safety and complications of endovasdcular stenting for symptomatic carotid stenosis with surgical high risk.Methods A series of 11 vessels in 9 patients at surgical high risk were treated by endovascular stenting. The complications during the procedures and postoperative periods were analyzed within one to five months. Results All of the operations were successfully performed without any serious complications. During the follow up period (averaging 6 months), there were no complications of TIAs, stokes and restenoses.Conclusions The study suggests that endovascular stenting may be safe and effective for patients at surgical high risk, but further more study is needed.

Objective The patient started from St. Louis (U. S.), and reached Chengdu (China) after 3 days of flight(St. Louis- Tokyo- Beijing - Chengdu). The patient felt unwell, so he and the two relatives took a taxi to the Emergency Center of Sichuan Provincial People' s Hospital for treatment. The epidemiological survey showed that, the patient had been living in the University of Missouri in the United States, no pigs died locally, there were no markets for the living pigs, farmers markets, farms, and slaughterhouses, and he hadn't contact with pigs. But 4 days before the onset, he closely contacted with a schoolmate, who had cold symptoms. The pa-tient had never been to virus laboratory 7 days before the onset. Clinical examinations showed that, the patient had a fever (37.8 ～ 38.8℃), WBC 7.9×10-9 L-1, N 5.475 × 10-9 L-1, L 19.5% ;the chest X-ray shewed that texture increased and the heart shadow augmented on both lungs; the result of throat swab culture was negative. The result of virus nucleic aeid detected by Sichnan Provincial Center for Disease Control showed H1N1 influenza virus, suspected. Sichuan Province Health organization organized experts on the prevention and control of H1N1 influenza for consultation, and the patient was diagnosed as the first suspected H1N1 influenza case in mainland China based on the epidemiological investigation, symptoms and signs of the patient, the results of laboratory ex-amination, and the result of virus test. Confirmed by the experts from Chinese center for disease control and pre-vention and The Ministry of Health of the People's Republic of China, the patient was diagnosed as the first H1N1 influenza case in mainland China.

Objective To investigate the detection of multidrug-resistant organisms (MDROs)in a hospital, evaluate the efficacy of multi-disciplinary team(MDT)on management of MDROs,and provide guidance for effective control on MDRO infection.Methods From October 2013 to September 2014,compliance to comprehensive inter-vention measures in clinical departments in different stages as well as detection of MDROs from patients were com-pared respectively.Results Compliance to comprehensive intervention measures showed an overall upward trend from the fourth quarter of 2013 to the first,second,and third quarters of 2014,difference was statistically signifi-cant (all P <0.001 ).From the fourth quarter of 2013 to the third quarter of 2014,the percentage of the major MDRO strains in the same species of bacteria were:methicillin-resistant Staphylococcus aureus (MRSA)52.34%, 45.45%,48.95%,and 26.25% respectively;carbapenem-resistant Acinetobacter baumannii (CRAB)64.42%, 63.07%,59.87%,and 43.09% respectively;multidrug-resistant Pseudomonas aeruginosa (MDRPA)42.11 %, 41 .82%,29.33%,and 17.52% respectively;the detection rate of MRSA,CRAB,and MDRPA showed an overall downward trend,difference among different stages were statistically significant (all P <0.001 ).Detection rates of carbapenem-resistant Enterobacteriaceae (CRE)and vancomycin-resistant Enterococcus (VRE)were both low (<5%),difference among different stages were not statistically significant (all P >0.05).Conclusion MDT on man-agement of MDROs is helpful for reducing the emergence and spread of MDROs.

Objective To analyze the change trend of hospitalized patients with pulmonary embolism in Wuzhou city during 2004-2014,and analysis of its risk factors.Methods From January 2004 to January 2014,from four comprehensive tertiary hospitals of Wuzhou city,we selected hospitalized cases of pulmonary embolism as investigation subjects,which from 2004 to 2008 were selected as control group,and from January 2009 to January 2014 were selected as observation group.The hospitalization rate,mortality rate and risk factors were compared between the two groups.Results From 2004 to 2008,there were 257 370 cases of hospitalized,pulmonary embolism hospitalized in 52 cases at the same period,accounting for 0.02％ of the total hospitalized cases.From January 2009 to January 2014,there were 367 728 cases of hospitalized,pulmonary embolism hospitalized in 115 cases at the same period,accounting for 0.03％ of the total hospitalized cases.The proportion of pulmonary embolism in total hospitalization between the two groups had statistically significant difference (P ＜ 0.05).From 2004 to 2008,in 52 cases of pulmonary embolism,24 cases (46.15％) died,includef 16 cases(30.7％) died of pulmonary embolism,and the rest 8 cases(15.38％) died of the complication.From 2009 to 2014,in 115 cases of pulmonary embolism,30 cases (26.08％) died,included 23 cases(20.00％) died of pulmonary embolism,and the rest 7 cases(6.08％) died of complications.The difference of the mortality rate in the two periods was statistically significant (x2 =3.879,P ＜ 0.05).52 cases of pulmonary embolism of the control group were selected to study risk factors and basic diseases,the risk factors and basic diseases of pulmonary embolism had 11 kinds,the highest frequency was in lower limb venous thrombosis,followed by surgery and lie in bed for a long time,again for malignant tumor,smoking,fracture,hyperlipidemia,arrhythmia(atrial fibrillation,etc.) and diabetes,etc.Conclusion The hospitalization proportion and mortality trend of hospitalized patients with pulmonary embolism in Wuzhou city remains unchanged,to study the risk factors in order to get a better prevention and treatment measures.