Clinical pharmaceutical services include: rounds by clinical pharmacists, monitoring of dynamics and adverse effects of drugs, pharmaceutical information services and analyses on use of drugs. Considering the difficulties that clinical pharmacists have encountered in clinical pharmaceutical services like ward rounds and different clinical knowledge structures, corresponding measures have been taken to assess the work load of clinical pharmacists so as to bring into full play the role of clinical pharmacists in clinical pharmaceutical treatment and information services.

AIM: To screen macroreticular resins for isolation and purification of flavonoids from the leaves of Diospyros kaki Linn (FLDK). METHODS: 8 kinds of macroreticular resins were assayed for their adsorbability and deadsorbability as well as the adsorption kinetics to FLDK. RESULTS: Polyamide and AB-8 resin were found with good adsorbability and deadsorbability as well as adsorption kinetics to FLDK. CONCLUSION: AB-8 resin and polyamide could be used for preparing high contents of FLDK. FLDK-P70, a flavonoid extract contained more than 77% of flavonoids was prepared from the extract of leaves of Diospyros kaki by polyamide adsorption column isolation.

Objective To assess the feasibility and clinical value of high-resolution magnetic resonance imaging (HRMRI) in patients with symptomatic severe intracranial stenosis (SSIS).Methods HRMRl wasperformed with a 3.0 T MR scanner on 5 patients with symptomatic middle cerebral(n=3) or basilar (n=2) arterial stenosis of≥70% confirmed bv DSA.Image diagnosis Was made on the basis of HRMRI findings of vessel wall at the stenotic segment by 2 neuroradiologists blinded t0 patient's status.Results Three of the five patients were diagnosed to have advanced intracranial atherosclerosis based on the presence of a complex eccentric atherosclerotic plaque containing a large lipid-rich necrotic core with a heterogeneous post-contrast enhancement and with signs of ruptured fibrous cap.Two other patients were likely to suffer from non-atherosclerotic lesion.HRMRI revealed an iso-signal septum in the arterial lumen attaching to the slighfly thickened arterial wall that was iso-signal with a homogeneous post-contrast enhancement in one patient and an obviously concentrically thickened arterial wall with hypo-intense signal on T1 WI and slightly high signal on T2 WI and PDWI and without any post-contrast enhancement in the remaining patient.Conclusions In vivo HRMRI in patients with SSIS is technically feasible.It provides detailed information of intracranial arterial wall at the stenotic segment.