1.Changes of superoxide dismutase and lipid peroxide in blood serum ulcerative of colitis patient
Basic & Clinical Medicine 2001;21(2):169-171
The content of superoxide dismutase (SOD) and lipid peroxide (LPO) of blood serum in 120 ulcerative colitis (UC) patient were tested by means of xanthine oxidation method and colorimeter on the reactive product of thio-barbituric acid.The content of SOD in the UC Patients was lower than that in the normal control group (P<0.001),and the content of LPO in the UC patients was obviously higher than that the control group (P<0.001).The content of SOD in the UC patients which accompanied the types of simple retention of damp-heat in the interior or weakness of the spleen and the stomach or the stagnancy of qi and blood stasis or deficiency of yin and stagnancy of qi and blood stasis was distinctly lower tban the one in the normal control groups (P<0.001).The content of LPO in them is distinctly higher than the content of LPO in normal control group (P<0.001).Conclusion: These results suggested that the content of SOD of protecting cell factor in the body of ulcerative colitis patients who were mostly the type of retention of damp-heat in the interior decreased and the content of LPO of damaging cell factor increased.When the patients accompanied with the deficiency,the content of the SOD in them reduced remarkably and the content of LPO enhanceed remarkably,especially in those who are the type of weekness of the spleen and the stomach or insufficiency of the spleen and the stagnancy of qi and blood stasis.
2.Clinical application of 3-D surface reconstruction by multislice spiral CT in the diagnosis of impacted teeth in maxilla
Journal of Practical Stomatology 2001;0(01):-
Objective:To evaluate the feasibility of the 3-D surface reconstruction by multislice spiral CT(MSCT) technique in the diagnosis of impacted teeth in maxilla.Methods:Eighty two cases with impacted teeth in maxilla were examined with volumetric CT scan using MSCT,the dental reconstruction images were obtained with multiplanar reformation technique and 3D-reconstruction technique.Results:Dental surface 3D-reconstruction image could display the shape,location and eruption orientation of the impacted teeth clearly.Conclusion:3-D surface reconstruction by MSCT can provide valuable diagnostic and anatomic information of the impacted teeth in maxilla.
3.Pharmacological Activity of Nest of Silvestri(Macrotermes annandalei)
Weijian BEI ; Yong CHEN ; Chaoshu CHEN
Chinese Traditional and Herbal Drugs 1994;0(09):-
Experimcnts showed that the nest of Macrotermes annandalei (Silvestri ) had the activity of relieving co gh, eliminating phlegm, and bacteriostasis. It coild also promote the phagocytosis of macrophages, enhance the transformation of T-cell of lymphocyte and rasiethe ratio of ANAE cell of lymphocyte in mice.
4.Clinical analysis on 5 cases of critically ill children complicated with pancreatic necrosis
Yimin ZHU ; Fang LIU ; Weijian CHEN
Chinese Pediatric Emergency Medicine 2011;18(2):120-122,后插一
Objective To summarize the clinical features and biological markers of critically ill children with pancreatic necrosis. Methods The clinical data of 5 ill children whose autopsy confirmed pancreatic necrosis in our hospital from 2003 to 2009 were collected and the pathological results were analyzed.Results Five cases appeared as acute onset and fever. Clinical manifestation of 2 cases included abdominal pain and 2 cases represented abdominal bulging,lots of flatulence and gastrointestinal bleeding. Four cases represented abnormal liver function and significant decrease of albumin,3 cases with increase of C-reactive protein. No case showed abnormal pancreas acoustic image of abdominal B-ultrasonography. Autopsy confirmed that 5 cases represented varying degrees necrosis of the pancreas, which complicated with the damage of adrenal gland,liver,lung,heart, spleen, kidney,intestine, thymus, mediastinal and mesenteric lymphnodes. All died in 36 hours after the children'conditions were changed. Two cases died of acute hemorrhagic necrosis of the pancreas,3 cases died of multiple organ failure based on pancreatic necrosis. Conclusion Pancreatic necrosis in critically ill children presents acute onset and short course,is prone to result in multiple organ damage or failure.
5.Association of vitamin D receptor gene TruⅠ and FokⅠ polymorphisms with lumbar degenerative disc disease in Han nationality
Weijian CHEN ; Wei YE ; Yue DING
Orthopedic Journal of China 2006;0(05):-
0.05.[Conclusion]VDR TruⅠ and FokⅠpolymorphisms are not related to LDD in Han nationality.
6.Comparative study of the circumcision techniques curative effect between circumcision suture device and Shang Ring
Shenquan CHEN ; Qifei ZHANG ; Weijian ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2015;(15):2318-2320
Objective To compare the clinical effectiveness among disposable circumcisionsuture device and Shang Ring in treating redundant prepuce and phimosis.Methods The clinical data of 224 cases of circumcisions done by disposable circumcision suture device(n =112)and Shang Ring(n =112)were retrospective1y analyzed. Operation time,intra -operational bleeding and postoperative complications among two techniques were compared. Results Disposable circumcision suture operation and Shang ring circumcision without significant difference in the operation time and intra -operational bleeding.There result was (6.1 ±0.8)min vs (6.5 ±1.7)min and (2.0 ±0.0)mL vs (1.8 ±0.0)mL(P >0.05).The incidence of postoperative complications with incision pain rate was 21.43% vs 50.89%,infection rate was 14.29% vs 6.25%,frenum area incision edema rate was 8.04% vs 25.89%,and the postoperative hematoma and healing time was (8.0 ±1.7)d vs (14.0 ±1.2)d,the differences were statistically significant(P <0.05).Conclusion Each of two techniques has its own advantages and disadvantages.The treatment decision making should be a detailed description to the patients,we propose that school -age children should choose Shang Ring built -in method and the others should use disposable circumcision suture device depending on the situation.
7.Implementing and understanding of clinical pharmaceutical services
Weijian LOU ; Gang HAN ; Huizhen CHEN
Chinese Journal of Hospital Administration 1996;0(12):-
Clinical pharmaceutical services include: rounds by clinical pharmacists, monitoring of dynamics and adverse effects of drugs, pharmaceutical information services and analyses on use of drugs. Considering the difficulties that clinical pharmacists have encountered in clinical pharmaceutical services like ward rounds and different clinical knowledge structures, corresponding measures have been taken to assess the work load of clinical pharmacists so as to bring into full play the role of clinical pharmacists in clinical pharmaceutical treatment and information services.
9.The Ethical Arguments of AIDS Prevention and Control for Colleges and Universities in China
Jinming SUN ; Lamei DENG ; Wenjun WU ; Weijian CHEN ; Yijia MA
Chinese Medical Ethics 2017;30(7):836-840
At present,the AIDS epidemic situation in college students is becoming more and more serious.In view of the particularity of colleges students and the lack of professional team for AIDS prevention and control in colleges and universities,there exists ethical issues when carry out the prevention and control for AIDS in colleges and universities such as the ethical issue in publicity and education,the ethical issue in AIDS behavioral intervention,the ethical issue in the consultation and detection for AIDS.This paper suggests that it should confront the current situation of AIDS prevention and control,improve the professional level of carrying out AIDS prevention and control,adhere to the necessary principles of AIDS prevention and control,and explore a new mode to construct AIDS prevention and control in colleges and universities.
10.Analysis of influencing factors of adrenal hemorrhage and necrosis in critically ill children
Xueli QUAN ; Yimin ZHU ; Xiulan LU ; Weijian CHEN ; Jun QIU
Journal of Chinese Physician 2017;19(7):988-991
Objective To investigate the adrenal histopathology damage in critically ill non-survival children,and the incidence of adrenal damage,and to explore the risk factors for the adrenal hemorrhage and necrosis in critically ill children.Methods A total of 141 critically ill non-survival children was admitted in this study in Hunan Children's Hospital from January 1,2005 to December 30,2012.Clinical data in children were systematically collected,including age,sex,sodium,potassium,blood gas analysis,liver and kidney function,blood clotting function,etiology,treatment and pediatric clinical illness score (PCIS) or neonatal critical illness score (NCIS),and pathological data.All data were analyzed by SPSS 18.0.Results Logistic regression analysis showed the factors of adrenal hemorrhage and necrosis of critically ill non-survival children were sepsis,PCIS score < 80 critically ill children are risk factors for adrenal hemorrhage necrosis (P < 0.05),ORwas 3.659 (95% CI:1.344-9.965),and 2.325 (95% CI:1.028 -5.258).Intravenous corticosteroids were protective factors for critically ill non-survival children with adrenal hemorrhage necrosis (P < 0.05),and ORwas 0.377 (95% CI:0.163-0.875).Conclusions There were two significant risk factors of adrenal hemorrhage and necrosis:sepsis and critical illness score less than 80 points.Intravenous corticosteroid is a protective factor in critically ill children.