1. Feasibility of 320 row wide-detector CT in evaluation on cardiac function in postoperative congenital heart disease children
Chinese Journal of Medical Imaging Technology 2020;36(9):1314-1318
Objective: To explore the feasibility of 320 row wide-detector CT in evaluation on cardiac function in postoperative congenital heart disease (CHD) children. Methods: Totally 25 postoperative CHD children underwent 320 row wide-detector CT and 3.0T MR cardiac scanning during following-up. The left and right ventricular ejection fraction (EF), end diastolic volume index (EDVI), end systolic volume index (ESVI), stroke volume index (SVI) and cardiac index (CI) were measured with corresponding cardiac function analysis software. The reproducibility of 320 row wide-detector results and their correlation with MRI results were compared and analyzed. Results: No significant difference of EF, EDVI, ESVI, SVI and CI was found between 320 row wide-detector CT and MRI results (all P>0.05), and CT results had good correlation with MRI(r=0.62-0.97, all P<0.05). The mean values of all index measured with CT were higher than those with MRI. The reproducibility of CT for measuring cardiac function indexes were good (ICC=0.85-0.98, all P<0.05). The volume index (EDVI, ESVI, SVI, CI) of left ventricular showed better reproducibility than that of the right ventricular. Conclusion: 320 row wide-detector CT could be used to evaluate cardiac function in postoperative CHD children, having a great value for those with contraindication for cardiac MR.
2.The clinical application of DWI signal intensity at different b values and ADC value in diagnosis of prostatic cancer
Weihui XIE ; Guojin XIA ; Honghan GONG ; Jian JIANG ; Xianjun ZENG
Journal of Practical Radiology 2019;35(6):981-984,1018
Objective To explore the value of DWI and ADC in differential diagnosis of benign prostatic hyperplasia (BPH)and prostatic cancer(PCa).Methods The data of 43 patients with BPH or PCa proven by histopathology were retrospectively reviewed. There were 21 patients with PCa and 22 patients with BPH.All of the patients were examined by DWI at 1.5T MRI.On the DWI,signal intensities in ROI were measured at the b value of 800 s/mm2 and 1 600 s/mm2 ,respectively.On the ADC map,ADC values in ROI were measured.The differences of the ADC values and the signal intensities of DWI were compared between the benign BPH and the PCa by using independent sample tGtest.Diagnostic efficiency of the signal intensity and the ADC value for PCa were analyzed by using ROC curve.Results There were statistically significant differences of the ADC values and the signal intensities of DWI at the b value of 800 s/mm2 and 1 600 s/mm2 between the BPH and the PCa (P<0.05).The ADC at the b value of 1 600 s/mm2 had the highest diagnostic efficiency,the DWI at the b value of 1 600 s/mm2 took a second place,and the DWI at the b value of 800 s/mm2 was worst.Conclusion DWI and ADC are helpful for the diagnosis of PCa,and ADC at b value of 600 s/mm2 has the highest diagnostic efficiency.
3.Clinical Study on the Sini-Moxibustion Therapy in the Treatment of Gastrointestinal Cancer Yang-Deficiency Patients with Fatigue Caused by Cancer
Jingyan XU ; Yanfei XIE ; Weihui LU ; Yingyue SHENG ; Xiaoli WEI ; Cheng LI
World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(11):2045-2050
Objective: To study the clinical efficacy of Sini-Moxibustion in the treatment of cancer-induced fatigue in patients with yang- deficiency gastrointestinal cancer. Methods: A total of 120 patients with gastrointestinal cancer treated in our department from January 2017 to January 2018 were randomly divided into 2 groups: the fire moxibustion group and the conventional group. The conventional group and the fire therapy group were treated with basic treatments such as anti-cancer and nutritional support. The conventional group added Sini-Moxibustion to the basic treatment, and the fire therapy group added"Sini-Moxibustion"therapy for a period of 1 month. Tthe indicators of the 2 groups of patients with Piper fatigue scale and grade, quality of life, symptoms of yang deficiency symptoms, clinical efficacy and blood tests of patients with chemotherapy were evaluated. Results: After the treatment, the degrees of fatigue in the fire moxibustion group was lower than that in the conventional group with statistically significant difference ( χ2 =4.24, P =0.037 < 0.05). The scores of improvement in the quality of life scale and five subscales in the fire moxibustion were higher than those in the conventional group with statistically significant difference (P < 0.01), and the improvement score of the body yang deficiency in the fire moxibustion group was greater than that of the conventional group (P < 0.01). The scores of fatigue, nausea and vomiting, insomnia, anorexia, and diarrhea in the fire moxibustion group were higher than those in the conventional group with statistically significant difference (P < 0.05 or P < 0.01). After treatment, the total effective rate was 76.67% in the fire moxibustion treatment group, which was higher than the conventional group 91.53% with statistically significant difference ( χ2 =5.64, P =0.012 < 0.01). Hemoglobin improvement value of 3.92 ± 1.18 in the fire moxibustion group was higher than that of the conventional group 1.02 ± 0.52 with statistically significant difference (t =7.212, P =0.003 < 0.01). Conclusion: Sini-moxibustion can improve the CRF of patients with yangdeficiency gastrointestinal cancer, reduce the symptoms of yang deficiency, improve the quality of life, and increase the hemoglobin content in patients with chemotherapy.