Prescription teaching is a routine task in medical colleges.However it is not a separate course,which can be undertaken by different teaching units or courses,and is not mentioned in training program.So,there are many problems in teaching practice,such as indefiniteness in responsibility,simplification of teaching settings,maladjustment to teaching and training objective and so on.Thus administrative department and major leaders should deepen the understanding of prescription teaching,take full account of its position in planning the training program,and make it more scientific to meet the needs of professional training.

0.05).CONCLUSION:Group C is the preferable one among the three groups.

The forepassed socialized medicine system for urban workers has many ethical faults. The institutional reform on the social medical insurance for urban workers will readjust the relationships between government, hospitals, employers and patients. It means much to ethics, and impulses the basic health service towards self-determination, duty and justice. But it has some problems about the responsibility of government,the sanction of hospitals and the burden of patients. At last,the paper offers some suggestions for improvement.

Objective To study the correlation between the polymorphism of Interferon γ( IFN-γ) ( + 874 T/A) gene and susceptibility to the development of lung cancer. Methods The polymorphism of IFN-7 gene( + 874 T/A) in 42 patients with lung cancer and 60 healthy control subjects was detected by using sequence-specific primers polymerase chain reaction( PCR-SSP) and their susceptibility to development of lung cancer was analyzed. Results The genotypic frequencies of AA of IFN -γ Gene( + 874 T/A) in the control group and the patient group were 0. 533, 0.786 .respectively and the genotypic frequency of AA in control group was significantly lower than that in the patient group ( P < 0. 01) , in contrast with which the genotypic frequencies of AT and TT in the control group were significantly higher than those in the patient group (P < 0. 01 ,P < 0.05). The A allele frequency of IFN-γ gene in the patient group was statistically higher compared with that in the control group(0. 869 vs. 0.7 ,P <0.01 ) ,in which the relative riskrate(RR) was 2.84,95%CI 1. 31 ~6.15 ,P<0. 01. Conclusion The polymorphism of IFN-γ gene ( +874 T/ A) could be associated with susceptibility to the development of lung cancer,so it could be considered one of the genetic markers to be used to early identify individuals at high risk of lung cancer.

OBJECTIVE: Dental implantation is one of effective method to repair defect and dentition. Therefore, it has wide perspective for clinical application. This study was designed to evaluate physicochemical property and clinical application of dental implant materials.METHODS: A computer-based online search was conducted in Medline for English language publications containing the key words of "dental implant, biocompatibility" from January 1999 to November 2009. Relevant data were also searched from CNKI with the same key words in Chinese from January 1999 to November 2009.RESULTS: With the development of medical materials, metal, ceramics, high polymer, composite materials, and nano-materials played important roles in dental implantation. Biochemical function, including biological morphology and correlation with adjacent soft and sclerous tissues, of the implanted teeth becomes a hot topic in modern tooth implantation. Nanometer technique, as a novel technique of living and life materials, becomes a hot research in oral implantology.CONCLUSION: Varying materials have been applied for tooth implantation, while nano-materials are developing for replacing traditional implant materials.

Objective: To explore the hemostasis mechanisms of Radix Rubiae and charred Radix Rubiae.Methods: The effects of Radix Rubiae and charred Radix Rubiae were compared in terms of the clotting time,bleeding time,blood platelets count and capillary permeability on mice,and the TT,PT and APTT on pathologicalbleeding models incurred by Heparin and Warfarin and rats.Results: Radix Rubiae and charred Radix Rubiaeall canrestrain the capillary permeability of abdominal cavity in mouse,and obviously shortenthe TT,PT and APTT of rat,but charred Radix Rubiae was more effective than Radix Rubiae.The large and small doses of Radix Rubiae and the large dose of charred Radix Rubiae can elevate the blood platelets count,and obviously antagonize Heparin and Warfarin,and Radix Rubiae was more effective than charred Radix Rubiae.Conclusion: Radix Rubiae has the hemostasis effect through elevating the blood platelets count and antagonizing Heparin and Warfarin,but charred Radix Rubiae through restraining the capillary permeability and shortening the TT,PT and APTT.They have different hemostasis mechanisms.

By means of the introarterial-injected preparations with oil dye(in some caseswith neuprene latex),the cerebral arterial circle and vertebral-basilar artery of camel(Bactrianus Camelus)were studied in 15 cases.The results obtained are as follows:1.The cerebral arterial circle is composed of two parts,and is formed by theinternal carotid artery intracranial segments and the caudal communicating arteriesas well as their branches of both sides,respectively.66.7 per cent of the caudalcommunicating arteries originate from the carotid rete,33.3 per cent from the inter-nal carotid artery intracranial segment.Anastomosis was found between these twovessels in 46.7 per cent and 20.0 per cent has no communicating branches.This isdifferent from other mammals.The average diameters of the two vessels are 0.216+0.057 cm and 0.178+0.056 cm,respectively.The circle gives the following vessels:rostral cerebral arteries,middle cerebral arteries,caudal cerebral arteries,and thecaudal segment of basilar artery.2.After receiving the branches of occipital artery,the vertebral artery entersinto the cranial cavity and divides to form the cerebral-spinal circle together withbranches on the opposite side.The circle gives rise to the caudal segment of basilarartery and ventral spinal artery.3.The course of the basilar artery differs in no way from the usual patternfound in other mammals,but it is of interest to note that the calibre of this vesselindicate the flow of the blood away the cerebral arterial circle as well as the cere-bral-spinal circle.The vessels arisen from the basilar artery are rostrol cerebellararteries,caudal cerebellar arteries,postpone branches and medullary branches.

Objective To observe the changes of carbohydrate antigen 19-9 (CA19-9) in type 2 diabetes mellitus (T2DM) patients,and determine the positive boundary value of CA19-9 for differentiating digestive tract malignant tumor and T2DM.Methods The clinical data of 300 cases were retrospectively analyzed.The patients were divided into 3 groups:group A with 100 T2DM patients,group B with 80 tumor patients and group C with 120 non-tumor and non-diabetic mellitus normal people.Chemiluminescence was used to determine the serum CA19-9 level,and the results of the 3 groups were analyzed.Results The serum CA 19-9 levels in group A and group B were significantly higher than that in group C [(21.38 ± 18.23),(32.21 ± 19.00) kU/L vs.(11.21 ± 10.08) kU/L],and there were statistical differences (P ＜0.05).Furthermore the serum CA 19-9 level in group B was significantly higher than that in group A,and there was statistical difference (P ＜ 0.05).The serum CA19-9 level was associated with fasting plasma glucose (r =0.527,u =5.144,P ＜ 0.01),2 h postprandial blood glucose (r =0.617,u =6.044,P ＜ 0.01),fasting insulin (r =0.427,u =4.144,P ＜ 0.01),and glycosylated hemoglobin (r =0.507,u =4.881,P ＜ 0.01),while the serum CA19-9 level was not associated with serum creatinine and courses of T2DM.CA19-9 ROC curve was used to determine 45.0 kU/L as the positive boundary value between the group A and group B.Conclusions The serum CA 19-9 level of T2DM patients is higher than that of normal people,but lower than that of patients with digestive tract malignant tumor.The serum CA 19-9 level is associated with blood glucose and glycosylated hemoglobin.The 45.0 kU/L as serum CA19-9 level positive boundary value can significantly improve the diagnosis value of digestive tract malignant tumor.

Objective To study the effects of different doses of atorvastatin on serum homocysteine (Hcy) and matrix metallopmteinase-9 (MMP-9) in patients with acute cerebral infarction.Methods Ninety-patients with acute cerebral infarction were randomly divided into two groups,the observation group (n =45 cases) and the control group(n =45 cases).The patients in the observation group were treated by the conventional therapy plus atorvastatin 40mg/d,while the patients in the control group were treated by the conventional therapy plus atorvastatin 20mg/d.Hcy and MMP-9 were detected before and after treatment for one month.Results The total effective rate was 95.6％in the observation group and 86.7％ in the control group.There was significant difference between two groups(x2 =2.1951,P ＜ 0.05).Hcy and MMP-9 were decreased after treatment in both groups and those in the observation group were lower than in the control group (all P ＜ 0.05).Conclusion High-dose atorvastatin can improve patients with acute cerebral infarction through decreasing Hcy and MMP-9.

Objective To observe the clinical effects of levocarnitine combined with sucrose iron injection for treatment of maintenance hemodialysis patients with renal anemia.Methods Forty-four cases of patients with maintenance hemodialysis merged renal anemia were randomly divided into control group (n =22) and treatment group(n=22).All patients were administrated conventional therapy.The sucrose iron injection was administrated with control group at hemodialysis, while treatment group administrated levocamitine after hemodialysis on this basis.The hemoglobin (Hb) and erythrocyte specific volume (Hct) were compared after treatment for 8 weeks,and the clinical effects were evaluated.Results After treatment for 8 weeks, the Hb and Hct(treatment group: (105.69±11.94) g/L, (0.31±0.04);control group: (86.31±11.39) g/L,0.27±0.05) had increased significantly compared with prior treatment(treatment group:(62.65± 12.74) g/L, (0.19±0.04;control group: (63.33 ± 13.23) g/L, 0.20± 0.06) in two groups, and the treatment group increased more significant than control group accompanied with significant statistically difference (t =3.197,2.978;P ＜0.05).Also,the total effective rate of treatment group was 86.4％(19/22) ,which higher than control group(50.0％ (11/22)) accompanied with significant statistically difference (x2 =6.705, P＜0.05).Conclusion The therapy of levocarnitine combined with sucrose iron injection can obviously improve anemia symptoms in patients with maintenance hemodialysis and worthy of popularization and application.