Objective To observe the effects of shenfu injection (SFI) on the awakening quality of the patients with hepatitis B cirrhosis undergoing splenectomy under general anethesia. Methods Forty patients with hepatitis B cirrhosis and hepatic insufficiency (ASA classⅡ~Ⅲ) underwent splenectomy by general anesthesia. Patients were all sent into the post-anesthesia care unit (PACU) shortly after the operation with unconscious and no spontaneously breathing. They were randomly divided into two groups: SFI treatment group (Group SFI, n =20) and normal saline controlled group (Group NSC, n = 20). SFI group were treated with SFI (1 mL/kg, i. v.) in 10 minutes, and NSC group were treated with normal saline (1 mL/kg,i.v.). The time of eyes opening, extubation of tracheal catheter and the detention time of PACU were recorded. The heart rate (HR) and the average artery presses (MAP) were monitored at 4 time points: before SFI and normal saline administration, 5 min, 15 min, and 45 min after administration. The incidence of restlessness during the patients awakening period was also recorded. Results The time of eyes opening, extubation and the detention time of PACU of SFI group show no significant difference compared with the NSC group (P > 0.05). SFI and normal saline intravenous injection did not cause significant changes on HR and MAP at the time of 5 min , 15 min and 45 min compared to the time of before administration (P > 0.05). The incidence of restlessness during the patients resuscitation period in SFI group were lower than in NSC group (P < 0.05). Conclusion Shenfu injection can effectively improve the awakening quality and decrease the incidence of restlessness of the patients with hepatitis B cirrhosis undergoing splenectomy under general anesthesia during the awakening period in PACU.

Objective　To compare the effects of early and long-term treatment with captopril on clinical outcome between elder patients (65-75 years old) and younger patients (＜ 64 years old) suffering from acute myocardial infarction (AMI). 　Methods　In a randomized trial, 822 patients with a first AMI were treated with captopril at initial dosage of 6.25 mg and adjusted to 25 mg t.i.d according to blood pressure (209 younger patients, 269 elder patients) and conventional treatment (131 younger patients, 213 elder patients). Survival rate of the four groups was calculated with Kaplan-Meier method. 　Results　The survival of treatment group was correlated significantly with age during hospitalization (P=0.0002). Eight patients in younger treatment group and 10 patients in younger control group (3.83% vs 7.63%, P＞0.05), 25 patients in elder treatment group and 52 patients in elder control group (9.29% vs 24.41%, relative risk = 0.37, 95% CI 0.29-0.48, P＜0.0001) were died. During follow-up period, the survival was however not related to the age (P＞0.05), and both the elder and younger patients had better survival (all P＜0.01 ) and lower cardiac events (all P＜0.01) during captopril treatment. 　Conclusions　 Captopril exerts less effect on the younger patients but more effect on the elder patients during hospitalization after AMI. Long-term captopril had no difference between the youngers and the elders in prognosis.

Objective To evaluate the therapeutic efficacy of intra aortic balloon supporting in coronary interventions for high risk patients with coronary artery disease(CAD).Methods Sixteen high risk CAD patients accepted percutaneous coronary intervention assisted by intra aortic balloon pumping together with clinical variables, procedural and follow up informations were recorded and evaluated. Results All patients presented with severe left ventricular dysfunction, multi vessel disease and high jeopardy scores. 12 patients acquired complete revascularization. Mean duration of balloon pumping was (31?17) minutes. Aortic diastolic and mean pressures were increased during balloon pumping [diastolic:(69?11)mmHg pre.vs (131?15)mmHg post.; mean:(82?13)mmHg pre.vs (111?7)mmHg post., P

Objective To compare the clinical utility of s7 and s670 intracoronary sents in the management of patients with coronary artery disease. Methods The clinical follow-up outcomes of 68 patients after implantation of s7 (n=32; group Ⅰ) and s670 (n=36;group Ⅱ) intracoronary stents were retrospectively analysed. Results The successful procedure rates were 100% in group Ⅰ and 97.2% in groupⅡ. The follow-up period was six months for both groups. In group Ⅰ, there were no death, no re-infarction and no revascularization but 2 patients experienced reccurrence of angina ( 6.25%). In group Ⅱ, there were 1 death, 1 patient undergoing revascularization, 3 patients suffering from reccurrence of angina ( 13.8%). Conclusions Both s7 and s670 intracoronary stents appear to be safe and effective in the treatment of coronary lesions with favorable outcomes.

Objective To study the relationship between sex hormones and uric acid in elderly women with coronary heart disease. Methods One handred and fifteen post menopausal female patients were divided into two groups by angiographic results, CAD group (n=61)and control group(n=76).Their serum concentrations of sex hormones and uric acid and general characteristics were compared. Results Baseline clinical characteristics were similar between the two groups,except patients in the CAD group were more likely to have hypertention and diabetes mellitus than the control group .Serum concentrations of estradiol and progestin and androgen showed little difference between CAD and control group,meanwhile, serum uric acid was higher(345.6?96.5 vs 307.9?85.5, P

Objective To evaluate coronary flow reserve (CFR) in patients with myocardial bridging.Methods Between September 2000 and January 2003, thirteen patients were detected myocardial bridging(MB) by coronary angiography(MB group). Another 32 patients with normal coronary arteries were served as a control group. Demographic information and CFR were compared between the two groups. Results All patients in MB group were presented with stable angina pectoris, and the systolic and diastolic coronary compressing stenosis were 78%?7% and 15%?5%, respectively. CFR in MB patients was significantly lower compared with the controls(2.0?0.3 vs 3.3?0.6, P

70), hypertension and multi vessel coronary artery disease.Conclusions Selective renal angiography immediately after coronary angiography is feasible and safe, and it exerts great significance of detection of RAS.

Objective To compare the effects of early and long term treatment with captopril on clinical outcome between elder patients (65 75 years old) and younger patients (0 05), 25 patients in elder treatment group and 52 patients in elder control group (9 29% vs 24 41%, relative risk = 0 37, 95% CI 0 29 0 48, P 0 05), and both the elder and younger patients had better survival (all P

Objective To evaluate the role of transeso phageal echocardiography(TEE) before chemical or electric cardioversion for non-vulvular atrial fibrillation. Methods Forty-three patients, confirmed non-vulvular atrial fibrillation, undertook anticoagulation or anti-platelet therapy and transthoracic echocardiography and TEE less than 24-48 hours prior to cardioversion. Results Two thrombi in the left atrial appendage and three spontaneous echo contrasts in the left atrium were evidenced. After anticoagulation or anti-platelet therapy, 39 patients undertook cardioversion therapy. Among them,31 patients received drug cardioversion,success in 19,and failure in 12;8 patients received electric cardioversion,success in 6,and failure in 2. There were no thromboembolic events during the hospitalization. Conclusions TEE performed before cardioversion for atrial fibrillation is necessary to reduce the risks of thromboembolic events and to guide for anticoagulation therapy.

Objective To evaluate the role of intravasc ular ultrasound (IVUS) in determining strategy for coronary artery stenosis of intermediate severity.Methods The study population consisted of 75 patients who had de novo coronary lesions of intermediate severity (40% to 70% diameter stenosis) in coronary angiography. IVUS examination was performed in all patients using standard methodology. Minimal lumen cross-sectional area (MLA) ≤ 4.0- mm 2 or percent area stenosis≥60% were identified as an IVUS index of functionally severe coronary stenosis, and used as an indication of coronary stenting. Major adverse cardiac events (cardiac death, acute myocardial infarction and recurrent angina) and the use of nitrates were recorded during follow-up. Results There were 44 patients (59%) with functional coronary artery stenosis, and all underwent successful coronary stenting. Acute coronary syndromes, soft plaque and positive coronary arterial remodeling were more common compared with the remaining 31 patients (41%) only treated medically. During a mean of (14?7) months of follow-up, there was no cardiac death and acute myocardial infarction. Readmission occurred in 5 patients (11%) due to in-stent restenosis in patients with interventional therapy and 4 patients (13%) due to exacerbation of coronary artery stenosis in patients with medical therapy. The use of nitrates was discontinued in 18(41%) and 14(45%) patients treated with interventional therapy and medical therapy, respectively. Conclusions It is valuable to perform IVUS examination in clinical decision making for intermediate coronary artery stenosis. IVUS criteria of MLA≤ 4.0- mm 2 or area stenosis≥60% may be a reliable index of functional coronary stenosis, determining the therapeutic strategy in patients with intermediate coronary artery stenosis.