The laboratory measurements for the diabetes mellitus are widely used in medical practice.The laboratory measurements should be accuracy and valuable for clinician.The "Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus"would be helpful for laboratorian and clinician in the diabetes care.

Various academic organizations, countries, and regions have established different concepts of metabolic syndrome, including the involvement of metabolic disorders, the threshold of its constituent elements,and the utility as a research or clinical tool, etc. Additionally, uncertainty of its pathogenesis, lack of uniform diagnosis definition, and some other factors lead to concept confusion and practical inconvenience of metabolic syndrome in public health prevention and in clinical diagnosis. Consensus and controversy of metabolic syndrome were both presented in recent years. Besides literature reviewing, further evidences are essential for appropriate understanding and distinguishing. The present article mainly introduces the new controversies concerning the concept of metabolic syndrome and the recent evidence of unifying trends in the diagnosis criteria of abdominal obesity in Asians.

Bone morphogenetic protein (BMP) family not only plays a role in bone formation,but is also involved in metabolic disease such as obesity and diabetes.The molecular structure,signal pathways,roles of BMP in regulating glycolipid metabolism,current situation and prospects in related diseases are mainly discussed.

Diabetes mellitus is a chronic metabolic disease caused by both genetic and environmental factors, it has a significant association with lifestyle. This paper mainly discusses the effects of diet, sleep, smoking,physical exercise, and lifestyle intervention that interact with genetics on diabetes.

Pharmacogenomics aims to identify the effects of genomie variants on drug efficacy and safety. This article summarized the progress of pharmacogenomic study on anti-diabetic drugs.

There is a close relationship between visceral adipose tissue and metabolic syndrome. It is necessary to enhance the researches on the inaccordance between the adipocytes of various depots and to elucidate the distinct differences between visceral and subcutaneous adipocytes in terms of their receptors, adipokines and activity of enzymes.

Recently,basic and clinical researches have shown that blood glucose variability is an independent risk factor for diabetic complications.Thus,ideal control of blood glucose is not only to reach the HbA1Ctarget,but also to minimize blood glucose variability.Different glycemic parameters could be selectedaccording to different purpose of evaluation,in which the mean amplitude of glucose excursions(MAGE) and the standard deviation of blood glucose (SDBG) could be used as accurate and simple assessment parameters respectively.

ncreased. But it remains controversial how vaspin is correlated with insulin sensitivity. More studies based on large population are needed to identify the associ-ation between vaspin and insulin sensitivity.

MATLAB Image Processing Toolbox (IPT) was used to analyze the filtered images and draw the gray value contrast curve respectively between cancerous and normal regions of liver tissue,and also detect the edge of the cancerous tissue region. Cancerous and normal region of 30 subjects were assessed with gray value curve. The change of cancerous region was significantly higher than the normal one. The gray value curve can effectively quantify the gray information of the image. Quantitative image parameters have an important reference value on the clinical diagnosis of liver cancer.

The deficiency in islet ?-cell secretion and (or) the decrease in insulin sensitivity of target tissue are the important pathophysiological mechanisms of diabetes. The methods for the assessment and evaluation of ?-cell function can be divided into: pulsatile insulin secretion, glucose secretagogues, non-glucose secretagogues (phase, peak value and duration) and other secretions. While the suitable method was chosen for the evaluation of ?-cell function, the sensitivity and specificity of different methods in the natural history of diabetes and the objective of evaluation should be all taken into account.