1.A survey of nonsteroidal anti-inflammatory drugs and aspirin associated peptic ulcer bleeding in hospitals
Zhiwei XIA ; Linlin MA ; Wei YAO
Chinese Journal of Internal Medicine 2011;50(2):111-115
Objective To investigate the clinical characteristic and prognosis of nonsteroidal antiinflammatory drugs( NSAIDs)and aspirin associated peptic ulcer bleeding. Method All patients with peptic ulcer bleeding were studied by the same researcher after admission and discharge. Results Fifty-one cases with NSAIDs and aspirin medication of the total peptic ulcer bleeding patients ( 147 cases) were included (34. 7% ). Compared with patients not associated with NSAIDs and aspirin medication, they are older [(41.2 ± 1. 9 ) years vs ( 59.4 ± 2. 2 ) years, P < 0. 001], more commonly associated with hypertension ( 10. 4% vs 39. 2% ,P <0. 001 ), coronary heart disease ( 10. 4% vs 17.6% ,P <0. 001 ) ,diabetes (4. 2%vs 19. 6%, P = 0. 005 ); and had more severe anemia (7. 3% vs 23. 5%, P = 0. 008 ). Fewer patients in NSAIDs group had epigastric pain (61.5% vs 27.5%, P < 0. 001 ), while there was more re-bleeding (9.4% vs 15.7%, P = 0.034). In all bleeding patients, factors associated with re-bleeding, surgical intervention and death included NSAIDs and aspirin medication, and low platelet count. In patients with NSAIDs and aspirin medication, re-bleeding was associated with previous ulcer history ( P < 0. 05 ).Conclusion Peptic ulcer bleeding patients with NSAIDs and aspirin medication were more severe ill, and less likely to present with epigastric pain.
2.Networked health information on diabetes: layer analysis
Mengmeng WEI ; Jingdong MA ; Chenxi XIA
Chinese Journal of Health Management 2013;7(6):394-397
Objective Networked health information on diabetes updated by some websites was evaluated to provide evidence for its improvement.Methods Twenty-four domestic diabetes-related websites were identified,and primary index (media index,health information index and diabetes information index) and secondary index (practicability index and novelty index) were evaluated by using hierarchal analysis method.Results Of three primary index,compared with media and health information index,diabetes information index showed higher scores.Moreover,health information and diabetes information had strong causality.For the secondary index,practicability and novelty got relatively lower scores.The website Diabetic Club and Health for All got the highest (3.2) and the slowest scores (1.7),respectively.Conclusion At present,domestic diabetes-related websites may be far from satisfaction and need improvement in technology and human resources and more inputs.
3.Expressions of angiogenin-1 mRNA and angiogenin-2 mRNA after focal cerebral ischemia in rat brain tissue
Shubei MA ; Wei SUN ; Xia LI ; Kangding LIU
Journal of Jilin University(Medicine Edition) 2006;0(01):-
0.05).In group I,the mRNA levels of Ang-1 were lower than those in group C during 3-6 h after onset of ischemia(P
4.Retrospective analysis of appropriate health technology policy in Zhejiang Province from 1991 to 2012
Yijia MA ; Wei ZHU ; Zhijun XIA ; Xin WEN ; Jianmin JIANG
Chinese Journal of Medical Science Research Management 2013;(2):102-103,114
This paper reviews the development of appropriate health technology policy from 1992 to 2012 in Zhejiang province.The evolvement of recent twenty years is classified into several stages and each is analysed and evaluated.This study provides reference for the establishment of appropriate health technology policy and the transformation of science and technology policy across the country.
5.Analysis of qualified military flying cadets by comprehensive assessment
Qing XIA ; Zhikang ZOU ; Jinjie SUN ; Wei LIU ; Zhongli MA
Military Medical Sciences 2015;39(12):895-899
Objective To provide an effective theoretical basis for future selection and recruitment of military flying cadets.Methods Two hundred military qualified flying cadets by comprehensive assessment samples and 200 military flying cadets by medical fitness samples were interviewed with questionnaires and subjected to a physical examination.The comprehensive assessment samples were classified by symptoms and attributive specialties for statistical analysis.A database was established, cleaned and analyzed by EpiData 3.02, SPSS 16.0 with double checking.Results There was no differ-ence between the comprehensive assessment team and the medical fitness team in age, areas, academic scores and psycho-logical performance.The ten top symptoms according to the comprehensive assessment were abnormal chest circumference, abnormal body mass,iris cyst,abnormal hypersplenotrophy,gallbladder polyps,flat foot,skin disease, intrahepatic calcifica-tion focus, joint disease and reproductive system disease.The attributed specialties included surgery, ultrasonics, ophthal-mology,ENT,radiology, ECG and internal medicine departments.The surgery and ultrasonics department contributed the most from the comprehensive assessment and accounted for 55.52%and 16.37%, respectively.Conclusion The compre-hensive assessment for military flying cadets has an important effect on military aviator selection.Continuous observation should be carried out among the military flying cadets by comprehensive assessment in their aviation training.
6.Protective Effect of Riptolide on Renal Tissures in Type 2 Diabetic Rats
Rui-Xia MA ; Li-Qiu LIU ; Yan XU ; Wei JIANG ;
Chinese Journal of Hypertension 2006;0(12):-
Objective To assess the renal protective effects of triptolide treatment in type 2 diabetic rats and its possible mechanisms.Methods Wistar rats were randomized to receive following approach control (n=7),dia- betic model without treatment (n=7) and diabetic group treated with triptolide[200 ?g/(kg?d),n=7].Plasma glucose (PG),serum creatinine (Scr),total cholesterin (TC),triglyeride (TG),kidney mass (KM),index number of kidney hypertrophy (KM/body mass,KM/BM),and 24 hours urinary albumin (24 h UAL) were determined. The protein expression of monocyte chemoattractant protein-1 (MCP-1),osteopontin (OPN) and ED-1 in renal tissue were determined by immunohistochemical technique.The mRNA expressions of MCP-1 and OPN in kidney tissue were assessed by reverse transcription-polymerase chain reaction (RT-PCR).Results Elevated 24 h UAL was markedly attenuated by triptolide treatment [24 h UAL,triptolide:2.32?0.29 vs diabetic model group:3.89? 0.51 mg/mgCr,P
7.Application of expanded skin flap in facial aesthetic and plastic surgery
Xianjie MA ; Yan ZHENG ; Wei XIA ; Wensen XIA ; Shuzhong GUO ; Yan HAN ; Kaihua LU
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(4):217-219
Objective To explore the aesthetic effect of the applying the expanded skin flap to re-pair facial defects produced by removal of nevus, hemangioma, scars and so on. Methods The experience of the treating 67 patients with facial lesions using the expanded flaps were reviewed. The proper expand-ers were chosen according to the scope of the facial lesion. The incision was located at the scar region and the dissection was executed in the superficial layer of the SMAS. The interspace was larger than the ex-pander by 1.0~1.5 cm. After exact hemostasis, the expanders and negative pressure drainage tubes were placed into the interspace. The design of the facial expanded skin flap included the advance, rotation, and transposition of skin flap and so on. The advance of skin flap took fully use of the expanded skin flap without the donor site defect. The transposition of skin flap also took fully use of the expanded skin flap, furthermore, it overcame the displacement and the disfiguration caused by the applying of the advance skin flap and rotation skin flap. The incisions in face were designed to a minimal extent and parallel to the Lan-ger line. Results All of the 67 cases got aesthetic satisfied results with all the flaps surviving. Conclusion The application of expanded skin flaps is proved to be an effective way of repairing facial wound when there is enough normal facial skin for expansion.
8.Comparison of Methods for Automatic De-identification of Clinical Texts
Liting DU ; Wei LUO ; Lei LI ; Bin LIN ; Chenxi XIA ; Guoqing MA ; Danni XIONG ; Jingdong MA
Journal of Medical Informatics 2017;38(4):44-49
The paper introduces the common methods for automatic de-identification of clinical texts,including the method based on rules,machine learning method,comprehensive method,etc.,states the challenges for clinical texts practicability,system universality and scalability of clinical texts de-identification research,analyzes the further research direction,and provides reference for researchers of this field.
9.An empirical study on medical selection of flying cadets with ear diseases between PLAAF and USAF
Wei LIU ; Zhikang ZOU ; Xiaoli MA ; Feng WANG ; Qing XIA ; Zhongli MA
Military Medical Sciences 2016;(1):16-19
Objective To determine whether the candidates who are disqualified because of ear diseases during medical selection of flying cadets in China are qualified or not according to United States Air Force ( USAF ) Medical Standards Directory in order to raise suggestions for revising PLAAF medical standards for flying cadets.Methods Data of final selections from 2013 to 2015 and the conclusions were compared by different standards.Results and Conclusion There was a marked difference (x2 =7.99,P<0.05) in the disqualification rate of cadets that rose each year.There was no difference (x2 =5.39,P>0.05) in the disqualification rate related to ear diseases.Vestibular dysfunction and dysacousis were the leading causes of disqualification among ear diseases, making up 45.54% and 38.84% respectively, with other diseases less than 5%.Medical standards for ear diseases in China are more strict than in the USAF, so we should revise some PLAAF standards according to the USAF standards for reference, such as those for vestibular neuritis, dysacousis and tympanic disease in order to enlarge the source of cadets.
10.Clinicopathologic features of adult granulosa cell tumor including unusual morphologic variants.
Xia LIU ; Gulinar ABULAJIANG ; Ming LIU ; Wei SANG ; Yu-qing MA ; Wei ZHANG ; Wen-tao YANG
Chinese Journal of Pathology 2013;42(1):44-45
12E7 Antigen
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Adnexa Uteri
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surgery
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Adult
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Aged
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Aged, 80 and over
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Antigens, CD
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metabolism
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Cell Adhesion Molecules
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metabolism
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Diagnosis, Differential
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Female
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Follow-Up Studies
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Granulosa Cell Tumor
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drug therapy
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metabolism
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pathology
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surgery
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Humans
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Hysterectomy
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methods
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Inhibins
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metabolism
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Middle Aged
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Neoplasm Recurrence, Local
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Neoplasm Staging
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Ovarian Neoplasms
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drug therapy
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metabolism
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pathology
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surgery
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Survival Rate
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Vimentin
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metabolism