Objective To analyze the effect of fiber bronchoscope bronchial lavage technique for the children with lobar pneumonia.Methods 110 cases of lobar pneumonia were divided into the bronchial lavage group (55 cases) and the control group (55 cases).The clinical effect of two groups was observed.Results The tempera-ture recovery time, chest rales recovery time, clinical presentation time, X -ray change recovery time of bronchial lavage groups were significantly shorter than those of the control group (all P<0.05).The total effective rate of the lavage group was 85.5%,which was 65.5% of the control group (χ2 =10.632,P <0.01).Conclusion The children with lobar pneumonia taken bronchoscopy and bronchoalveolar lavage reached the diagnosis and achieved the goal of treatment,it could significantly improve the clinical symptoms,promote disease recovery,conducive to rehabili-tation of children.

[Summary] Colorectal cancer is the one of the most common malignancies in the world .Currently, surgery is the main treatment for colorectal cancer .Although laparoscopic surgery for colon cancer has been widely accepted , laparoscopic approach for rectal cancer is still in clinical trials .At present, several trails have shown that the short-and long-term outcomes of laparoscopic rectal cancer resection are similar with open surgery , but others have shown that pathological outcomes and total resection rates of laparoscopic surgery are unsatisfactory .Laparoscopic rectal cancer surgery needs more grade Ⅰ evidences .Nowadays , researchers are exploring new ways to treat rectal cancer .

Thyroid-associated ophthalmopathy (TAO) is an inflammatory eye disease associated with thyroid autoimmune disorder.The traditional treatments have yielded limited efficacy but with some side effects.Recently,researches have shown that some new immunosupressants may be used for the treatment of TAO with significantly improved symptoms,and reduction in clinical activity score.

Objective To investigate whether the skin-derived neural stem cells inducted by the culture could survive,differentiate and migrate in the lesioned site of rat spinal cord.Methods The skin of new born rat trans-gene of green fluorescence protein(GFP) was applied to be dissociated into cells,cultured and inducted to proliferate in vitro.Skin-derived neural stem cells were identified by immunocytochemistry staining.Then,skin-derived neural stem cells inducted by the culture were transplanted into the lesioned site of rat spinal cord hemisection.Thirty days and sixty days after the operation,the survival,migration and differentiation of transplanted cells were observed by immunocytochemistry staining. Results Ten days at cultured skin-dissociated cells,many cell-spheres had been formed by the proliferation of suspensive growing cells.These cell-spheres showed nestin positive staining of immunocytochemistry.It suggestes that the cell-spheres are neurospheres.In vivo,many transplanted skin-derived neural stem cells with GFP were observed in the lesioned area of spinal cord.Some transplanted cells migrated into host spinal cord tissue far away from the lesioned area.Some transplanted surviving cells showed nestin,MAP2 and GFAP positive staining of immunocytochemistry separately.Conclusion Skin-derived neural stem cells inducted by the culture may survive,migrate and differentiate into neuron-like cells and astrocyte-like cells in injured spinal cord of rat.

Objective To explore the effects of Ganoderma spore(germination activated Ganoderma spore) on survival and expression of neurotrophin_3(NT_3) and nitric oxide synthase(NOS) of injured motor neurons in rat spinal cord. Methods Different dosages of Gandoerma spore were irrigated into the rat's stomach respectively in experimental groups after oneside ventral root cut.The survival ratio of injured motor neurons was counted.NT_3 expression of surviving motor neurons was measured by immunohistochemistry and in situ hybridization methods and NOS activity was measured by enzymo_histochemistry method. Results Thirty_five days after ventral root cut,the survival ratio of motor neurons was 47.32% in control group,and those were 67.11%,72.67% and 81.67% respectively in low,medial and high dosage Ganoderma spore groups.Expressions of NT_3 and NOS of surviving motor neurons in high dosage Ganoderma spore group were higher than those in control group.Conclusion Ganoderma spore may promote the survival of injured spinal motor neurons,and survival ratio of injured motor neurons is related to the dosages of Ganoderma spore.Ganoderma spore may also enhance the expressions of NT_3 and NOS of surviving spinal motor neurons.

In 2020, the Chinese Society of Endocrinology released a new version of the consensus on acromegaly. This article aims to interpret in details on three aspects of treatment goals, surgical treatment, and radiotherapy in this concensus.

Objective To explore the effect of out-hospital health education on quality of life of heart failure patients with dilated cardiomyopathy. Methods 60 cases of heart failure patients with dilated cardiomyopathy were selected and divided into follow-up group and control group with 30 cases in each group. The follow-up group accepted out-hospital health education, while the control group only accepted conventional in-hospital health education. Then World Health Organization Quality Of Life-Brief (WHOQOF-BRIEF) was used to evaluate their quality of life 6 months after discharge. Results The score of WHOQOF-BRIEF was higher in the follow-up group than in the control group (P<0.05). The satisfactory degree of nurse-patient relationship was better in the follow-up group than in the control group (P<0.05).Conclusion Out-hospital health education can improve the quality of life of heart failure patients with dilated cardiomyopathy.

Objective To explore the express levels of CA199,CA724 and CEA in different gastric mucosa pathological situation.Methods The experimental group included 82 cases including 15 of chronic atrophic gastritis,15 of intesti- nal metapiasia,15 of dysplasia of the gastric mucosa,19 of gastric ulcer,18 of gastric cancer;15 of the chronic Super- ficial gastritis (CSG) were set as control group.To test express levels of CA199,CA724 and CEA in these cases by the immunohistochemistry technology.Results The positive rate of CA199,CA724 and CEA in gastric cancer was sig- nificantly higher than that in precancerous lesion groups and precancerous state groups (P0.05),but there was a graduate increasing of the positive rate of CA199,CA724 expression in chronic atrophic gastritis,intestinal metaplasia and dysplasia of the gastric mucosa. Conclusion That different expression of CA199,CA724 and CEA in gastric cancer development situation may be help- ful for the early diagnose of gastric cancer.