1.Primary malignant pericardial mesothelioma:clinicopathological and immunohistochemical analysis
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To explore the clinicopathological and immunohistochemical features of primary malignant pericardial mesothe- lioma.Methods Seven cases of primary malignant pericardial mesothelioma,in 4 females and 3 males,with the age ranged from 22 to 51 and a mean of 40 years old,were studied with clinicopathological,immunohistochemical and histochemical techniques,The pertinent litera- ture was also comprehensively reviewed.Results 3 biopsy specimens and 4 surgical specimens,including 2 autopsy specimens,were stud- led.The main clinical symptoms were palpitation and short breath,which were aggravated after movement.The longest course was 4 years,and the mean disease course was 12 months.The chest films demonstrated an obviously increase in heart shadow,and the pericardi- um was thickened in some cases.CT clearly showed tumorous shadow in 2 cases.The histopathologic picture showed tubular type in 2 ca- ses,papillary in 2,signet ring cell type in 1 and myofibroblast types in 2.In 2 autopsy specimens it was found that pericardium was dif- fusely thickened.In one case the tumor was metastasized to the right lung,mediastinum,and pulmonary hilar lymph node.In another case there was metastasis to right kidney.Immunohistochemical staining showed that the neoplastic cells of all cases were positive for CK5/6, calretinin,CK.vimentin and EMA,but negative for CEA.In the histochemical staining seven cases,the malignancy was positive for CI to different extent,but negative for HCL Conclusion Immunohistochemistry and histochemistry play an important role in diagnosis and dif- ferential diagnosis for primary malignant mesothelioma and other tumors in pericardium.
2.Retrospective study on the treatment of severe asthma
Wei LONG ; Gang LU ; Juan XIE ; Wei LU ; Yu ZHANG
Clinical Medicine of China 2008;24(7):700-701
Objective To evaluate the effect for the treatment of severe asthma. Methods The data of 47 patients with severe asthma who were admitted to emergency department were retrospectively anayzed. Results Of total 47 patients ,45 were rescued, with the survival rate of 95.7%. Arterial blood gas was improved after treatment (P < 0.01). Conclusion Appropriate commencement, mode, strategy, and early weaning of mechanical ventilation, combined with the administration of bronchodilators and eorticosteroids are the important way to rescue patients with severe asthma.
3.Influence of Reproduction Methods on Volatile Oil of Pogostemon cablin Benth.
Liangwen YU ; Yanzhu ZHONG ; Wei LI ; Gang WEI ; Xiaoming XU
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(04):-
Objective To compare the volatile oil and constituent content in Pog ostemon cablin Benth. propagated by cuttage and tissue culture. Methods The vola tile oil assay of Chinese pharmacopoeia and GC-MS method were used. Results The volatile oil and constituent content of Pogostemon cablin Benth. reproduced by cuttage was 14.2 mL/kg and 81.31 %,respectively. The volatile oil and constituent content of Pogostemon cablin reproduced by tissue culture was 12.2 mL/kg and 82.98 %,respectively. Conclusion The volatile oil content and constituent content of Pogostemon cablin Benth. reproduced by tissue culture are similar to which reproduced by cuttage.
4.Diagnosis and treatment of the right ureter adenocarcinoma: report of one case.
Yu-gang LI ; An-yang WEI ; Da-peng YU
Journal of Southern Medical University 2006;26(5):583-583
Adenocarcinoma
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diagnosis
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surgery
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Aged
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Humans
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Male
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Treatment Outcome
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Ureteral Neoplasms
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diagnosis
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surgery
5.Efficacy and safety of dapoxetine in the treatment of premature ejaculation.
Xiao-yu CHEN ; Ying-wei QU ; Suo-gang WANG
National Journal of Andrology 2016;22(5):411-414
OBJECTIVETo evaluate the clinical effect and safety of dapoxetine in the treatment of premature ejaculation (PE).
METHODSWe randomly assigned 116 PE patients to receive dapoxetine on demand at 30 mg qd (dapoxetine group, n = 60, aged 23-49 years) or oral tamsulosin at 20 mg qd (control group, n = 56, aged 24-46 years). After 4 weeks of medication, we compared the clinical global impression of change (CGIC) , PE profile (PEP) scores, intravaginal ejaculation latency time (IELT) , and adverse reactions between the two groups of patients.
RESULTSCompared with the baseline, the IELT was remarkably prolonged after treatment both in the dapoxetine group ([0.86 ± 0.17] vs [4.32 ± 2.23] min, P < 0.05) and the control ([0.88 ± 0.15] vs [4.17 ± 2.26] min, P < 0.05), with no statistically significant difference between the two groups (P > 0. 05). The post-treatment rate of CGIC in the dapoxetine group had no statistically significant difference from that in the control (85.00% vs 82.14%, P > 0.05). In comparison with pre-treatment, the patients of both the dapoxetine and control groups showed dramatically improved scores after medication in perceived control over ejaculation (0.85 ± 0.23 vs 2.13 ± 0.97 and 0.88 ± 0.21 vs 2.06 ± 0.34, both P < 0.05), ejaculation-related personal distress (1.15 ± 0.64 vs 2.89 ± 0.26 and 1.19 ± 0.53 vs 2.82 ± 0.69, both P < 0.05), satisfaction with sexual intercourse (0.81 ± 0.33 vs 2.58 ± 0.37 and 0.79 ± 0.28 vs 2.45 ± 0.32, both P < 0.05), and ejaculation-related interpersonal difficulty (2.05 ± 0.61 vs 3.24 ± 0.35 and 2.03 ± 0.65 vs 3.18 ± 0.76, both P < 0.05), with no significant differences between the two groups (P > 0.05). The incidence of adverse reactions was significantly lower in the dapoxetine than in the control group (3.33% vs 30.36%, P < 0.05).
CONCLUSIONDapoxetine is effective for the treatment of PE, with its advantages of prolonging the intravaginal ejaculation latency time, improving the quality of sexual life, and low incidence of adverse reactions.
Adult ; Benzylamines ; administration & dosage ; therapeutic use ; Coitus ; Double-Blind Method ; Ejaculation ; Humans ; Male ; Middle Aged ; Naphthalenes ; administration & dosage ; therapeutic use ; Patient Satisfaction ; Premature Ejaculation ; drug therapy ; Serotonin Uptake Inhibitors ; administration & dosage ; therapeutic use ; Sexual Behavior ; Sulfonamides ; administration & dosage ; therapeutic use ; Treatment Outcome ; Young Adult
7.Clinical observation of biopsy by double paths for higher positive percentage.
Hong-Quan WEI ; Gang YU ; Xiao-Tian LI ; Zhong REN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(1):67-68
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Biopsy
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methods
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Child
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Child, Preschool
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Endoscopy
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Female
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Humans
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Larynx
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pathology
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Male
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Middle Aged
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Nasopharynx
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pathology
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Young Adult
8.Discussion on relationship between soft tissue tension and cervical physiological curvature change of patients with scapular muscle fasciitis.
Yong ZHAO ; Wei FANG ; An YAN ; Gang WANG ; Chun-Yu LIU
China Journal of Orthopaedics and Traumatology 2014;27(5):376-378
OBJECTIVETo discuss the relative association of soft tissue tension and cervical physiological curvature chang in patients with scapula muscle fasciitis.
METHODSFrom February 2012 to December 2012,29 patients with scapula muscle fasciitis were investigated. There were 10 males and 19 females with an average age of 27.77 years old (ranged from 22 to 40 years old). Routine AP and lateral cervical X-rays were done in all patients. Cervical lordosis was measured according to Borden's method and the pain point tension was measured by soft tissue tension meter. Finally,perform statistic analysis to bove data.
RESULTSLateral X-rays showed 9 cases were normal cervical lordosis, 18 cases were cervical lordosis decreased, 2 cases were cervical lordosis increased. The regression equation of cerical lordosis changes D(Y) and soft tissue tension displacement D0.5 kg (X) was Y = -15.069 + 3.673X.
CONCLUSIONThere is linear relationship between soft tissue tension and cervical physiological curvature change. With the soft tissue tension increases, the cervical lordosis trend to decrease.
Adult ; Biomechanical Phenomena ; Cervical Vertebrae ; pathology ; physiopathology ; Fasciitis ; pathology ; physiopathology ; Female ; Humans ; Male ; Mechanical Phenomena ; Scapula ; pathology ; physiopathology ; Young Adult
9.Observation on therapeutic effect of acupuncture combined with medicine on mild cognition disorders in patients with post-stroke.
Wei LI ; Yan-Hong CHENG ; Xiao-Gang YU
Chinese Acupuncture & Moxibustion 2012;32(1):3-7
OBJECTIVETo explore the curative effect and safety of acupuncture for mild cognitive disorders after stroke.
METHODSRandomized controlled trial was adopted and one hundred cases conforming to criteria were divided into a combined acupuncture and medication group (group A) and a medication group (group B), 50 cases in each group. The basic treatment of cerebrovascular disease was applied in two groups. The group A treated was with acupuncture at Baihui (GV 20), Shenting (GV 24) and Qucha (BL 4) etc. and oral administration of Nimodipine. In group B, Nimodipine was taken orally. The treatment lasted for 3 months, the scores of Mini-Mental State Examination (MMSE), modified Hasegawa Dementia Scale (HDS-R) and Barthel Index (BI) were observed before and after treatment in two groups.
RESULTSThe total effective rate in group A was 66.7% (32/48), which was superior to 30.4% (14/46) in group B (P < 0.05). The scores of MMSE, HDS-R and BI after treatment were apparently improved as compared with those before treatment in two groups (all P < 0.01). The improvements in group A were superior to those in group B (all P < 0.05). There was no adverse event reported during the treatment in two groups.
CONCLUSIONAcupuncture can improve activity of daily living and has significant effect in treating mild cognition disorders after stroke without adverse reactions.
Acupuncture Therapy ; Aged ; Cognition ; Cognition Disorders ; etiology ; psychology ; therapy ; Female ; Humans ; Male ; Middle Aged ; Stroke ; complications ; Treatment Outcome
10.Diagnosis and treatment strategy of primary ureteral fibroepithelial polyp
Gang WANG ; Liping ZHANG ; Wei YU ; Liqun ZHOU
Chinese Journal of Urology 2014;35(3):178-181
Objective To summarize the diagnosis and treatment strategy of primary ureteral fibroepithelial polyp.Methods The Clinico-pathological data of 44 primary ureteral fibroepithelial polyp cases (27 males and 17 females) treated from Jan.1998 to Mar.2013 were analyzed retrospectively.The mean age was 37 (12-67) years.Patients were admitted with flank-abdominal pain (63.6%),painless gross hematuria (18.2%) and hydronephrosis (9.1%) with a mean history of 4 (1 week-20 years) yrs.CT scan of the 38 cases revealed hydronephrosis (68.4%) and ureter tumor (63.2%).Of the 16 cases with retrograde urography,13 demonstrated filling-defects in ureter (81.3%),among whom,10 revealed long strip-shaped filling-defects suspect of ureter polyp (62.5%).Ureteroscopy was performed in 25 cases and discovered ureter polyp in 19 patients.Partial ureterectomy was performed on 28 patients,endoscopic procedure was performed on 11 cases and the left 5 patients were treated with nephroureterectomy.Results 40 patients were followed-up for 6 mon to 15 years.Of the 35 patients with the kidney reserved,31 were fully recovered with no symptoms and with no hydronephrosis or polyp recurring,3 cases with hydronephrosis were relieved,1 patient lost the affected kidney after 3 years because of severe hydronephrosis.Conclusions Primary ureteral fibroepithelial polyp should be suspected in younger patients with long term intermittent flank or abdominal pain and/or gross hematuria.CT scan and retrograde urography are the main diagnostic imaging studies.Ureteroscopy plays a pivotal role in the diagnosis and decision of treatment strategy,especially to avoid undertaking nephroureterectomy in suspicious of ureteral carcinoma.Resection of the polyp under ureteroscopy is safe and effective.