1.Comparison the effect of Shengxuening tablets and ferrous succinate in treating pregnancy with anemia
Feng ZHANG ; Fuqun ZHOU ; Weidong WEI
Chinese Journal of Biochemical Pharmaceutics 2017;37(2):68-71
Objective To compare the clinical efficacy and safety of anemia during pregnancy of Shengxuening tablets and ferrous succinate treatment for clinical treatment in patients with anemia .Methods 212 cases of pregnancy in early pregnancy patients with anemia from March 2015 to February 2016 in our hospital,numbered according to the order of treatment, were randomly divided the patients into group A and group B,106 cases in each group,group A with Shengxuening tablets treatment, group B with ferrous succinate tablets treatment,two groups of patients were treated with the same program of diet guidance,all patients were treated for three months.Each patient was followed up to the end of delivery, and the two groups of patients before and after pregnancy treatment to the end of pregnancy anemia and pregnancy outcomes were compared.Comparison of two groups of patients before and after treatment for one,two and three months of hemoglobin (Hb) level,red blood cell count (RBC),serum ferritin (SF),total iron binding rate (TIBC) changes;finishing treatment of the two groups during the three follow-up of Hb, RBC, SF TIBC, which returned to normal levels at the time and, after three months of treatment and evaluate the clinical efficacy of the two groups were collected and compared during the treatment of adverse drug reactions of two groups were compared.Results After treatment for one,two and three months, levels of Hb,RBC and SF in two groups of patients were significantly higher than those before treatment,TIBC was lower than that before treatment (P<0.05);After treatment for one and two months,RBC,SF and Hb in group B were significantly higher than those in group A,TIBC lower than group A(P <0.05);After treatment for three months,the levels of Hb, RBC, SF and TIBC in two groups were back to normal,and there was no significant difference between the two groups.Hb, RBC,SF,TIBC index recovery time of group B was significantly shorter than the group A (P<0.05).After treatment for three months,there was no significant difference in clinical efficacy between two groups.The adverse drug reaction rate was significantly higher in the group B than in the group A during the treatment period (P<0.05).The end of the treatment to the end of pregnancy, five cases of group A were again the parallel treatment of anemia, 11 cases of group B were again anemia and pregnancy outcome in patients with treatment ,the adverse pregnancy rate in group A was higher than that of group B, the difference was statistically significant (P<0.05).Conclusion Shengxuening tablets and succinate iron treatment of early pregnancy anemia have advantages and disadvantages,clinical can consider the combined treatment of anemia in pregnancy,improve the clinical efficacy and safety.
4.Influence of cervical curvature change on the nerve root and vertebral artery of patients with cervical spondylosis and clinical observation of manipulation treatment
Guikang WEI ; Jian WEI ; Honghai ZHOU ; Binbin ZHOU ; Feng CHEN ; Rong HUANG ; Xinjiao LI
Journal of Integrative Medicine 2003;1(4):259-61
OBJECTIVE: To observe the influence of the change of cervical curvature on the nerve root and the vertebral artery of the patients with cervical spondylosis and the curative effect of therapeutic manipulations. METHODS: Sixty cases of cervical spondylosis with the change of cervical curvature, 60 cases of cervical spondylosis without the change of cervical curvature and 60 normal people were chosen. They were clinically observed and the cervical spondylosis was treated by manipulations and the data was processed according to the principle of statistics. RESULTS: The change of cervical curvature affected the nerve root and the vertebral artery and therapeutic manipulations produced a satisfactory curative effect. CONCLUSION: Cervical spondylosis with change of cervical curvature has special characteristics in the etiology, course and state of the disease. The change of cervical curvature produces an effect on the nerve root and the vertebral artery. Selected therapeutic manipulations produce a better curative effect.
6.Application of proteomic techniques in pediatric research.
Wei-qin ZHOU ; Xiang-yong KONG ; Zhi-chun FENG
Chinese Journal of Pediatrics 2011;49(7):526-530
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methods
7.Practice and evaluation of PBL teaching method in stomatology
Wei ZHOU ; Xiping FENG ; Jianzhong ZHANG ; Jiawei ZHENG
Chinese Journal of Medical Education Research 2013;(6):587-590
Objective To investigate the satisfaction degree of students and teachers towards PBL teaching method and to provide a basis for continuing to carry out PBL teaching.Methods Anonymous questionnaires of PBL teaching method in teaching plan and procedure was conducted among 49students (2008 grade) and teachers.SPSS 13.0 software package was used to analyze the data and P < 0.05 stands for statistically significant differences.Results Both students and teachers were satisfied.Teachers' evaluation scores of 17 projects were all higher than 4 points and students' evaluation scores of 13 projects were all higher than 4 points; scores for the rest projects were all higher than 3 points.Conclusions PBL teaching method combined with stomatology is effective and measures should be taken to strengthen the management of PBL teaching in stomatology.
8.Clinical analysis of hyperthyroidism complicated with periodic paralysis
Huang WEI ; Li YING ; Luo YAN ; Zhou FENG
Chinese Journal of Primary Medicine and Pharmacy 2011;18(17):2356-2357
Objective To explore relevant factors of hyperthyroidism with periodic paralysis of hypokalemic (TPP).Methods The clinical data of 112 cased with hyperthyroidism complicated periodic paralysis of hypokalemic were retrospectively analyzed and to analyze the relevant factors. Results Compared to control group, the hyperthyroidism with periodic paralysis group had no obvious differences in general factors ( P > 0. 05 ), but had obvious difference in Gender( P <0. 05 ) ;Compared to control group, the hyperthyroidism with periodic paralysis group had obvious differences in induction factors(P < 0. 05);Compared to recurrent group, the incipient group had no obvious differences in several factors( P >0. 05) ,but had obvious difference in hyperthyroidism medical history over one year( P <0. 05) ; Hyperthyroidism with periodic paralysis was strongly associated with hypokalemia, age, gender, tiredness, getting a cold, satiation and hyperthyroidism genetic history ( P < 0. 01 ). Conclusion The relevant factors of hyperthyroidism with periodic paralysis were hypokalemia, gender, tiredness, getting a cold, intemperance, satiation and hyperthyroidism medical history.
9.Analysis of the diagnosis by X-ray in 327 patients with cervical spondylosis
Feng ZHANG ; Gang ZHOU ; Shunsheng WANG ; Wei JIN
Chinese Journal of Primary Medicine and Pharmacy 2011;18(z1):5-6
Objective To discuss X-ray signs of cervica spondylosis.Methods Complete information on 327 cases of cervical spondylosis was analyzed retrospectively.Results These were 245 cases of vertebral spur,accounting for 75% ;210 cases of cervical curve changes,accounting for 62% ; 154 cases of disc stenosis,accounting for 47 % ; 137 cases of forainal stenosis stenosis,accounting for 42% ;135 case of luschka j iont degeneration,accounting for41% ;124 cases of neck ligament calcification,accounting for 38%.Conclusion Vertebral bone spur,luschka jiont degeneration and disc and foraminal stenosis were important signs of cervical spondylosis.X-ray diagnosis of cervical spondylosis had an important value.
10.Studies on processes for preparation of QINGXUE JIANGZHI CAPSULE
Shuhua FENG ; Jing ZHOU ; Wei QIAO ; Jingwei FU ; Xiaomei ZHANG ;
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To establish a process for the preparation of QINGXUE JIANGZHI CAPSULE(Hemocathartic Antilipemia Capsule) Methods The study was carried out by uniform experimental design guided by the content of total organic acid and polysaccharide in the resulting preparation, to optimize the ratio of solvents used for the extraction, time needed for the decoction and alcoholic concentration for precipitation Results The most favorable preparative conditions were: decocting the drug twice with 10 times of water for 60 min each time, and precipitate the product at a concentration of 50% alcohol Conclusion Products prepared by this process ensured the content of total organic acid with no loss of polysaccharides