Objective To analyze the detection rate of lung cancer during 2009-2013 in Shaoxing of Zhejiang province and its time trend. Methods The data of lung cancer in Shaoxing from 2009 to 2013 with a total coverage population of 21 970 825 person-year (male 10 993 657 person-year, female 10 977 168 person-year), was collected to calculate the detection rate, age adjusted detection rate, percentage change of incidence (PC), etc. The annual percentage change (APC) of incidence was estimated by linear regression based on the logarithm of the incidence rates observed. Results During 2009-2013, a total of 9 973 new cases were diagnosed as lung cancer with the sex ratio of male to female being 2.44∶1. The detection rate of lung cancer was 45.39/100 000 (male 64.35/100 000, female 26.41/100 000), age-standardized detection rate by Chinese standard population (ASR China) was 20.09/100 000 (male 28.37/100 000, female 11.66/100 000), age-standardized detection rate by world standard population (ASR world) was 27.26/100 000 (male 37.83/100 000, female 15.73/100 000). The cumulative rate and truncated rate of those aged 0-74 and 35-64 were 3.40% (male 4.80%, female 1.91%) and 39.90/100 000 (male 54.44/100 000, female 24.81/100 000). The detection rate of lung cancer increased from 34.29/100 000 in 2009 to 59.91/100 000 (APC=13.88%, P=0.006<0.05), among males the detection rate increased from 50.60/100 000 to 82.91/100 000 (APC=12.52%, P=0.011<0.05), and the female detection rate increased from 17.81/100 000 to 36.78/100 000 (APC=17.70%, P=0.005<0.05). In Shaoxing, the detection rate of lung cancer increased obviously among the residents over 45 years of age. For each age group except 15-and 20-, the male detection rate was higher than the female incidence. Conclusion The men who were 45 years and older were at a higher risk of lung cancer in Shaoxing. The detection rate of lung cancer increased year by year from 2009 to 2013 in Shaoxing, especially among women over 65 years of age.

Radionuclide MPI is an important noninvasive modality for the diagnosis of coronary artery disease.The current clinically useful MPI tracers,201Tl and 99Tcm labeled agents,have limitations.Some known ligands bound with 99TcmN core might be promising MPI agents because of their high chemical stability.This review summarizes the structure,biodistribution and imaging characteristics of the 99TcmN core labelled MPI tracers with emphasis on several agents having promising prospects for future applications.

Objective To analyze the detection rate of thyroid cancer from 2009 to 2013 in Shaoxing of Zhejiang province and its time trend.Methods The data of thvroid cancer in Shaoxing from 2009 to 2013 was collected to calculate the detection rate,age adjusted detection rate and percentage change of incidence,and the annual percentage change (APC) of incidence was estimated by linear regression based on the logarithm of the incidence rates observed.Results lDuring 2009-2013,a total of 3 290 new cases were diagnosed as thyroid cancer with the sex ratio of male to female being 1 ∶ 3.69.The detection rate of thyroid cancer was 14.98/100 000 (male 6.39/100 000,female 23.59/100 000),with age-standardized detection rate by Chinese standard population (ASR China)9.13/100 000(male 3.94/100 000,female 14.31/100 000),and age-standardized detection rate by world standard population(ASR worll) 10.39/100 000(male 4.47/100 000,female 16.32/100 000).The detection rate of thyroid cancer increased from 7.26/100 000 in 2009 to 27.26/100 000 (APC =39.65％,P＜0.05),with the detection rate among males increasing from 2.42/100 000 to 12.65/100 000(APC =48.44％,P＜0.05),and the detection rate among female increasing from 12.15/100 000 to 41.96/100 000(APC =37.58c％,P＜0.05).In Shaoxing,most of the new thyroid cancer cases were from 25 to 59 years old,and the highest incidence happened in the group of 50-54 years.For each age group,the detection rate in female was almost over two-folls higher than the incidence in male.Conclusion The detection rate of thyroid cancer was increased year by year from 2009 to 2013 in Shaoxing,especially among the young and middle-aged women.The corresponding measures must be taken to control the risk factors of thyroid cancer.

Objective To analyze the incidence of malignant tumor in Shaoxing of Zhejiang Province in 2012.Methods Descriptive analysis was carried out based on our chronic disease monitoring information management system.Age-standardized incidence was calculated according to Chinese standard population in 1982 and the Segi's world population.Results The crude incidence of malignant tumor was 291.34/100 000,age-standardized rate by Chinese standard population (ASR China) and by world population was 137.29/100 000 or 176.72/100 000,respectively.The cumulative rate of the 0-74 years old group was 20.27％ and the cut rate of the 35-64 years old group was 301.49/100 000.Male crude incidence of cancer and ASR China were 330.46/100 000 and 149.28/100 000,respectively; for female,the figure was 251.93/ 100 000 and 124.79/100 000,respectively.The crude incidence and ASR China were 364.85/100 000 and 171.77/100 000 in urban area residents,and 277.86/100 000 and 130.93/100 000 for those living in rural areas.Age-specific incidence of the 0-29 years old group remained low,although the incidence was increased after 30 years old and reached the peak in the 80-84 years old group.The most common malignancy were lung cancer,gastric cancer,colorectal cancer,liver cancer,breast cancer,thyroid cancer,esophageal cancer,pancreatic cancer,cervical cancer and leukemia (76.77％).Conclusions Lung cancer,gastrointestinal cancer and female reproductive system cancer were most common malignancy in Shaoxing of Zhejiang Province in 2012.The incidence of thyroid cancer,leukemia and brain tumor is significantly increased over the past few years,which may need effective control and prevention strategies.

Objective To observe the function changes of right ventricular in chronic obstructive emphysema after lung volume reduction surgery. Methods Twenty-six patients with chronic obstructive emphysema undergoing lung volume reduction surgery were examined by color Doppler echocardiography to determine systolic function and diastolic function of right ventricle in preoperative days and postoperative days of 5～7; 12～14; 1 month and 3 months. Results Contraction of right ventricle: comparing with preoperative parameters, there were significant decrease (P0.05) of those above mentioned in postoperative days 12～14. It recovered at 3 month after operation. Relaxation of right ventricle: the swift filling peak flow-rate in earlier relax period (E) and E flow-rate integra (ETVI) decreased meanwhile swif filling peak flow-rate in late relax period (A) and A flow-rate integra (ATVI) increased in the postoperative days 5～7 (P

Objective To observe the effect of pulse microwave combined with antibiotics on chronic prostatitis.Methods100 outpatients with chronic prostatitis were randomly divided into the trail group and control group with 50 cases in each group. The patients of the trail group were treated with pulse microwave combined with Ofloxoacin, and those of the control group were treated only with Ofloxoacin. The treatment course was 5 weeks. The evaluation with National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) and test of white blood cell (WBC) count in prostate secretion were performed before and after treatment for all patients of two groups.ResultsIn the trail group, the mean symptom degree score of NIH-CPSI was 9.3±2.6 and living quality score was 3.4±1.2, the total score was 12.4±4.1, and WBC count was 13.7±5.4/HP. In the control group, these indexes were 13.3±3.5, 4.5±1.2, 17.5±4.6 and 17.1±5.2 respectively. The NIH-CPSI score and WBC count of the trail group were lower than that of the control group ( P<0.05), and cure rate and total effective rate were higher than that of the control group ( P<0.05).ConclusionThe treatment of pulse microwave combined with Ofloxoacin for chronic prostatitis can improve the cure ratio and efficiency.

Objective To explore the diagnostic values of dual energy lung perfusion in the diagnosis of pulmonary embolism by using dual-source CT (DSCT). Methods Thirty patients with clinically suspected pulmonary embolism underwent dual-energy scanning with dual-source CT. The scanned data were integrated into three groups including 140, 80 kV and coefficient of 0.3. According to the CT pulmonary angiography (CTPA) of the fusion data, the patients were divided into pulmonary embolism group and normal group. The thin-slice reconstruction of data was analyzed using dual-energy perfusion imaging analysis software. The lung field was divided into upper, middle and lower part to make quantitative analysis of lung tissue perfusion. Paired t-tests were used in the normal patients to compare bilateral lungs, and independent samples t-tests were applied to compare the embolism group and normal group, while minimum intensity projection images (MinIP) were utilized in the assessment of lung ventilation. Results Dual energy CT showed symmetrical homogeneous perfusion in 16 normal cases, without significant perfusion defects. Quantitative analysis showed that left and right lung perfusion were (27 ± 7) and (28 ± 8 ) HU respectively, and no significant difference was found between the two sides ( t=-1.73, P ＞0.05 ).Perfusion of the left upper, middle and lower lung was ( 23 ± 6), (24 ± 6), and (28 ± 8) HU respectively, while the perfusion of right upper, middle and lower lung was (26 ±8), (27 ±8), and (28 ±9) HU respectively, showing no statistical significant difference between the two sides (t=-1.91, -1.96,-1.73 ,P＞0.05 ). Angiography of pulmonary embolism group(14 cases)showed filling defects in the pulmonary trunk, segments and sub-segments. Pulmonary perfusion imaging showed low perfusion or defectsin lung field that dominated by embolic vessels. Quantitative analysis showed that the perfusion of the whole lung and the middle and lower lung were (22 ±5), (22 ±8), and (21 ±8) HU in the embolism group,which were significantly different from the normal group (t=-2. 10, -2.32, -2.63, P＜0.05).Minimum intensity projection images showed a good consistency of abnormal ventilation zone area and perfusion abnormalities. Conclusions Pulmonary perfusion status, especially pulmonary embolism, can be analyzed by dual energy CT scanning. It helps to early discover and precisely locate the embolism.

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Adolescent ; Adult ; Drug Industry ; Hematologic Tests ; Humans ; Middle Aged ; Occupational Exposure ; Platinum Compounds ; blood ; Workplace ; Young Adult

Objective To discuss the clinical application value of ultrasound contrast on evaluating fallopian tube patency.Methods Ultrasound contrast examination was conducted on 84 patients suffering from infertility and the flowing status of contrast agent in the uterine cavity and the fallopian tube and the distribution condition in the pelvic cavity were observed under the real -time ultrasound to judge the patency condition of the fallopian tube.Results After 84 patients receiving ultrasound contrast,38 cases'bilateral fallopian tubes were unobstructed,26 cases'lateral fallopian tube were unobstructed and 20 cases'bilateral fallopian were obstructed.Comparing the result of ultrasound contrast with laparoscopy,the diagnosis accuracy was 89.5%,the specificity 86% and the sensitivity 94%.Conclusion Fallopian tube ultrasound contrast technique can make an accurate and objective evaluation on the fallopian tube patency,it is an effective method to check fallopian tube patency and it is of high clinical application value.