1.Diagnosis and prognosis of systemic juvenile rheumatoid arthritis.
Li-hua SHAO ; Min WEI ; Mei DONG
Chinese Journal of Pediatrics 2003;41(1):46-47
Arthritis, Juvenile
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classification
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diagnosis
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therapy
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Child
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Female
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Follow-Up Studies
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Humans
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Male
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Prognosis
2.Progress in the studies of prostate cancer related molecules.
Wei SHI ; Li DONG ; Jun-sheng BAO
National Journal of Andrology 2015;21(4):357-362
Prostate cancer is one of the common malignant tumors of the urinary system and mostly found in elderly men. Like most tumors, prostate cancer involves a variety of molecules in its occurrence and progression. More studies on the development of prostate cancer focus on the tumor markers, DNA damage repair related genes, and tumor invasion and metastasis related factors. This article presents an overview on the research progress in these three aspects.
Biomarkers, Tumor
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Biomedical Research
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DNA Repair
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Disease Progression
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Humans
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Male
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Neoplasm Invasiveness
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Prostatic Neoplasms
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genetics
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pathology
3.Chinese Herbal Medicine Washout Combined with Lactic Acid Bacteria Vaginal Capsule Treat Refactory Vaginitis 500 Cases
Hairong LI ; Xueqin WEI ; Lihong DONG
Journal of Zhejiang Chinese Medical University 2013;(10):1215-1217
[Objective]To investigate the clinical effect of Chinese herbal medicine washout combined with lactic acid bacteria vaginal capsule on refractory vaginitis. [Method] Divide 500 patients into 3 types: downward flow of damp-heat, damp toxin implication, internal heat due of Yin deficiency, which treated with different decoctions with lactic acid bacteria vaginal capsule. Fol ow up for 3m after treatment course, observe recurrence; make vaginal secre-tion tests before and after treatment. [Result] In downward flow of damp heat type, 139 cases were cured, 11 effective, the total effective rate 100%; on damp toxin implication type, 183 cases were cured, 13 effective, total effective rate 100%;for internal heat due to Yin deficiency, 141 were cured, 9 effec-tive and total effective rate 100%. There’s no recurrence after 3m. [Conclusion] The said method can effectively regulate vaginal micro-ecological envi-ronment and reduce recurrence of refractory vaginitis, with safe clinical application and definite cure effect.
4.Risk factors for the failure of INSURE strategy in very and extremely low birth weight preterm infants
Wei LI ; Dong XU ; Liwen CHANG
Chinese Journal of Neonatology 2017;32(5):325-330
Objective To study the risk factors for failure of INSURE strategy in very and extremely low birth weight preterm (V/ELBW) infants.Method From January 2005 to December 2014,clinical data of 149 preterm infants (gestational age less than 32 weeks) admitted to neonatal department of Tongji Hospital who received intubation-surfactant-extubation (INSURE) strategy were collected.These infants were assigned into two groups:INSURE failure group and INSURE success group,according to whether a second dose of surfactant or mechanical ventilation was needed within 72 hours after first pulmonary surfactant treatment.The clinical characteristics and outcomes between the two groups were compared.Chi square and t tests were used to define the differences between groups.Logistic regression analysis was used to identify the independent risk factors for INSURE failure.Result Among the 1 149 patients,148 received INSURE treatment,and 113 cases (76.4%) were successfully treated with the INSURE strategy.The infants in the failure group were statistically lower in birth weight,gestation age,antenatal steroids utilization rate,PaO2 and PaO2/FiO2 than those in the success group,while the age of mother,male/female ratio and PaCO2 were higher in the failure group.Logistic regression analysis showed that male (OR =7.440,95% CI 1.846 ~29.984),BW < 1 000 g (OR =9.180,95% CI 1.716 ~49.105),PaCO2 >48 mmHg (OR =5.996,95% CI 2.088 ~ 17.213),PaO2/FiO2 <205 (OR =3.010,95% CI 1.033 ~8.774) were independent risk factors for INSURE failure.Conclusion INSURE strategy failure was associated with gender,birth weight,gestation age,antenatal steroids utilization,PaO2,PaCO2 and PaO2/FiO2 of the first blood gas after birth.BW < 1 000 g,PaCO2 > 48 mmHg and PaO2/FiO2 < 205 of the first blood gas after birth were independent risk factors for INSURE strategy failure.
5.Treatment of lumbar disc heniation with limited spinal stenosis by microendoscopy discectomy
Shouren WEI ; Rongzhu LI ; Dong YIN
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
0 05). Conclusions Microendoscopy discectomy via laminoctomy has advantages of less trauma and quicker recovery.It is safe and effective in the treatment of lumbar disc heniation with limited spinal stenosis.
6.Design and development of institutional scientific research management information system
Changqin LI ; Jinghui WEI ; Dong WU
Chinese Journal of Medical Library and Information Science 2014;(11):65-67,74
After the institutional scientific research management at present was analyzed according to the literature investigation, expert consultation, comparative and comprehensive analysis, the following were advanced, including the principles, target, function module and structure module for institutional scientific research management infor-mation system , and realization of its functions using the J2 EE technology-based B/S framework .
7.Modern Research of Calculus Bovis (Third) : Preparation Technology
Wei LI ; Chengliang ZHANG ; Dong LIU
Herald of Medicine 2017;36(3):237-240
The preparation of Calculus bovis and its compounding preparations have been used widely in clinical practice.Traditionally,the forms of medicine were in raw material medicine way,preparing tablet,pill,powder or directly taking its powder.The main active ingredient of Calculus bovi were considered to be bilirubin and bile acids.However,the traditional formulations caused low bioavailability and wasted expensive herbs because its main component were insoluble in water.In recent years,many researchers have tried to use modern preparation technology to prepare its compounding formulations,such as solid dispersion technology,ultrafine grinding technology,powder coating technology,liposome encapsulation technology,or simplifying the prescription by using of known pharmacological effects of soluble components as substitutes.These methods were considered to be feasible to develop new formulations of Calculus bovis.In this paper,in order to provide reference of method and technology for the improvement of Calculus bovis compounding preparation and the development of new dosage form,ultramicrostructure,chemical composition,improvement methods and techniques of compounding preparation were analyzed.In addition,the relevant techniques and method of improving the formulation Calculus bovis compounding preparation in recent years were reviewed.
8.Clinical analysis of chronic cough caused by postnasal drip syndrome.
Yong-Dong YAN ; Li HUANG ; Wei JI
Chinese Journal of Contemporary Pediatrics 2008;10(1):79-80
Adolescent
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Child
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Child, Preschool
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Chronic Disease
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Cough
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etiology
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Female
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Humans
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Male
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Rhinitis
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complications
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diagnosis
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drug therapy
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Sinusitis
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complications
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diagnosis
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drug therapy
10.Difference of the treatment response of the different clinical COPD phenotypes to inhaled salmeterol and fluticasone
Li DONG ; Xufang SHANG ; Xiujuan WEI
Journal of Chinese Physician 2015;17(2):236-238,242
Objective To compare the treatment responses of the inhaled salmeterol and fluticasone (50/500 μg) for three months in the different clinical phenotypes of chronic obstructive pulmonary diseases (COPD) which were chronic bronchitis phenotype and emphysema phenotype and to explore the difference of the treatment responses.Methods To enroll and follow up the stable COPD patients from outpatient department who received the treatment of inhaled salmeterol and fluticasone (50/500 μg).Patients with low attenuation area (LAA,the density on CT scan <-950 HU) ≥15% of the while lung area% (LAA%) were defined as emphysema group,while patients with LAA% < 15% were defined as chronic bronchitis group.All the subjects received lung function test before and after three-month treatment.Results Totally,84 patients (49 male and 35 female patients) with stable COPD were enrolled with an average age (61.04 ±9.23) years old,30 patients in emphysema group and 54 patients in chronic bronchitis group.Before treatment,forced expiratory volume in one second (FEV1) % predicted value and residual volume (RV) % predicted value in emphysema group were lower than those of chronic bronchitis group (P =0.04 and P =0.01),while inspiratory capacity (IC)% predicted value was higher than that of chronic bronchitis group (P =0.02).After three-month salmeterol and fluticasone inhalation treatment,FEV1 and RV were improved in both groups,but FEV1 and RV in chronic bronchitis group were improved more significantly than those of emphysema group (P =0.02 and P =0.03).Conclusions The treatment responses of different clinical phenotypes of COPD to inhalation of combination of salmeterol and fluticasone were different,chronic bronchitis phenotype had better treatment response compared to emphysema phenotype.