Perioperative nutrition support may be required when the synthesis and utilization of nutrients become disordered due to gastrointestinal abnormalities and trauma anesthesia. Proper nutrition support can reduce or prevent malnutrition, and thus facilitate the recovery and lower complications and case-fatality rate.

Objective: To analyze the chemical constituents of the essential oil extracted from the seeds of Myristica fragrans Houtt.(nutmeg) in Indonesia and to provide qualities control scientific foundations.Methods: The essential oil was extracted by steam distillation and separated with GC capillary column.The relative content of every compound was determined by normalization method and the chemical compositions were evaluated by GC-MS.Results: Ninety-three chromatographic peaks were isolated and sixty-one compounds were identified,accounting for 97.62% of the total essential oil in nutmeg.Conclusion: The essential components of nutmeg in Indonesia is monoterpenoids and it's derivatives,accounting for 78.87% of the total essential oil.And phenolic compounds were the secondary composition,accounting for 16.79%.The essential oil contains safrole,which can induce genetoxicity and mutagenicity in animal,and myristicin and elemicin which can induce illusion.So,it must be careful when Myristica fragrans Houtt was used.

Scapulohumeral periarthritis,alternate name‘lujianfeng’or‘jianlingzheng’,is a common disease among the old.Balance acupuncture is a science of modern acupuncture based on the traditional theory of Chinese medicine.In order to sum up the references regarding the clinical treatment features and experimental study of balance acupuncture on scapulohumeral periarthritis in the past few decades.The review shows that as a new modern acupuncture method,balance acupuncture treating scapulohumeral periarthritis is worth to master,popularize to develop and innovate.

Objective To study the protective effect of total glucosides of Mudan cortex(TGM) on acute myocardial ischemia in mice and its mechanism. Methods The total of 60 mice were randomly divided into 5 groups (n = 12),normal control and model control (were given equal capacity of 0.9% sodium chloride solution),and TGM at low,middle,high dose (were given with 50,100,200 mg?kg-1 TGM).The mice were administered once daily for consecutive seven days.After the last administration,the mice in the model control and drug groups were treated by intraperitoneal injection of 15 mg ? kg-1 isoproterenol to to make myocardial ischemia animal model. TGM on the T wave and J point on ECG, and serum lactate dehydrogenase (LDH),myocardial tissue superoxide dismutase (SOD),malondialdehyde (MDA) changes was detected,and the extent of myocardial ischemic injury in mice was measured by Nagar-Olsen staining. Results TGM significantly reduced the displacement of ECG T wave and J point,and improved the related biochemical indexes in mice with myocardial ischemia.The activity of LDH [(898.992± 285.108) μmol?mg-1 ] ,the content of MDA [(11.737 ±5.162) nmol?mg-1 ]in mice treated with TGM at high dose obviously decreased in comparison to the model controls,and the activity of myocardial SOD [(45. 505 ± 20.711) U?mg-1 ] significantly elevated compared with the model control.It was showed that TGM significantly diminished the areas of cardiac muscles ischemia injured via Nagar-Olsen staining. Conclusion TGM has the remarkable protective effect on acute myocardial ischemia injury in mice.

Auditory Perception ; physiology ; Child Development ; physiology ; Hearing ; physiology ; Humans ; Infant, Newborn ; growth & development ; Intensive Care Units, Neonatal ; Noise ; adverse effects

ObjectiveTo explore the application of peripherally inserted central venous catheter (PICC)and central venous catheter (CVC) in the surgical parenteral nutrition.MethodThe operation time,success rate,indwelling duration,abnormal biopsy,and adverse reactions of PICC and CVC were retrospectively compared.ResultsCVC had significantly shorter operation time than PICC groups [ (28.67 ±5.13) min vs.(45.20 ±6.89)min,P =0.035 ).The mean indwelling duration was significantly longer in PICC group than in CVC group [ ( 114.85 ± 10.29) d vs.(24.78 ± 8.42) d,P =0.033 ].PICC group was superior to CVC group in terms of five complication items,while only phlebitis was more frequent/severe in CVC group.ConclusionsPICC may be more suitable for long-term ( ＞4 weeks) catheter-based nutrition.CVC has short operation time and fast flow rate,and therefore is most suitable for rescue treatment for critically ill patients.

Hedgehog (HH) signaling pathway is a classic signaling pathway which controls embryonic development.Recent studies show that HH signaling pathway plays an important role in the tumorigenesis and development of cancer.Breast cancer stem cells (BCSCs) is closely associated with malignant tumor metastasis,relapse and treatment resistance.HH pathway plays crucial roles in maintaining the characters of BCSCs,and will probably become a novel therapeutic target of breast cancers.

Objective:To study the significance of standard operating procedures of construction emergency medical simulation teaching-based. Methods:Emergency medical simulation teaching base on the construction of standard operating procedures mode. Results:SOP model was used in emergency medicine in practice teaching and management, it improved the connotation of practical teaching system construction;and was helpful to improve the practice teaching content construction. Evaluation is beneficial to improve the practice teaching system. Evaluation is beneficial to improve the practice teaching system. To strengthen the emergency medical simulation base radiation ability, promote the standardization of practice teaching and management level, this itself is a kind of innovation, but still need to constantly improve and improve. Conclusion:Explore with Chinese characteristics of Chinese and western medicine combined with emergency medicine education mode, cultivate high-quality talents in the field of traditional Chinese and western medicine emergency.

Objective: To observe the effect of Yufeng Capsule (Radix Astragali, Radix Salviae Mitiorrhizae, Rhizoma Gastrodiae, etc) on the moisture content, activity of Na +,K + AT Pase and Ca 2+ ATPase in brain tissue of rat with ischemia reperfusion.Methods:the model with ischemia reperfusion was established by line embolism method, the moisture content and activity of ATPase in brain tissue of model rat were determined respectively at ischemia 2h reperfusion 1h and ischemia 2h reperfusion 24h.Results:Yufeng Capsule could significantly decrease moisture content of rats brain, increase the activity of Na +,K + ATPase and Ca 2+ ATPase.Conclusion:Yufeng Capsule could prevent and treat the cerebral edema caused by ischemia reperfusion, its mechanism may be related to improving cytomembrane ionic transport after ischemia reperfusion.

Objectives To study the effect of ubiquitin proteasome inhibitor bortezomib on apoptosis and Caspase-3 expression in human umbilical arterial vascular smooth muscle cells. Methods Human umbilical artery vascular smooth muscle cells were cultured in vitro. Different doses of bortezomib (0, 4, 10, 40nmol/L) were used to treat cell. Cell proliferation activity were detected by using CCK8 method. Western Blot assay was used to measure the expression of Pro-caspase-3 and Cleaved-PARP protein. Morphology of cells in different groups are observed by confocal microscopy and apoptosis rate were detected by flow cytometry analysis. Results Bortezomib inhibits proliferation activity of vascular smooth muscle cells. With increasing of drug concentration and treating time, cell viability are reduced (P < 0.01). Cells treated with different concentrations bortezomib for 48 h showed increased apoptosis rate (P < 0.01), decreased pro-caspase-3 protein expression and increased cleaved-PARP protein expression (P < 0.01). Laser confocal microscope found that with the increase of drug concentration, the number of apoptotic cells showed an upward trend under per high-power vision. Conclusion The ubiquitin proteasome inhibitor bortezomib may decrease the expression of pro-caspase-3 and increase Cleaved-PARP expression in human umbilical artery vascular smooth muscle cells. Additionally , it could induce apoptosis in a dose-dependent manner.