2.Theory and Practice on Construction of TCM Jaundice Thematic Database
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(5):848-851
The traditional Chinese medicine (TCM) literature database of jaundice is an important means of the realization of the standardization and digitalization of TCM liver disease syndrome differentiation and treatment.
This article analyzed the background of jaundice literature database and its establishment and significance . The building of TCM jaundice database was described in this paper from literature data source, TCM jaundice the-saurus, literature collection and analysis. A brief introduction was made on contents of the database and the function. Deficiencies of the literature database such as the standardization, quality, daily maintenance, talent and team training were also explained .
3.Hope for the patients with retinitis pigmentosa
Wei-jing, YIN ; Li-ya, WANG ; Wei, WANG ; Feng, PAN
Chinese Journal of Experimental Ophthalmology 2011;29(2):97-100
Retinitis pigmentosa (RP) is a hereditary disease characterized by the progressive loss of photoreceptor cells. Disease pathology primarily affects rod photoreceptor cells first but light-insensitive cone photoreceptor bodies can survivor longer. Delivered by adeno-associated viral vector or lentiviral vector, expression of microbial-type rhodopsin, channelrhodopsin-2 or archaebacterial halorhodopsin in the survived retinal cells can substitute for the native phototransduction cascade in mouse models of retinitis pigmentosa. It can also restore light sensitivity and activate all retinal cone pathways and drive sophisticated retinal circuit functions. Thus, expression of channelrhodopsins or halorhodopsin might be a potential strategy for the restoration vision of patients with RP.
5.Characteristics of Violence Behavior of Psychotics in Communities
Yue WANG ; Shu-li WEI ; Ya-min WANG ; Jing DING
Chinese Journal of Rehabilitation Theory and Practice 2006;12(7):610-612
ObjectiveTo explore the characteristics of violence behavior of the psychotics in communities. Methods37 psychotics who used to have violence behavior were investigated with Questionnaire of Characteristics and Associated Factor for Violence Behavior of Psychotics in Communities created ourselves. ResultsThe psychotics suffered violence behavior appeared some peculiarities for the time, place, and dealing with tools, etc. Their mental state, course of disease and treatment were associated with their violence behavior. ConclusionThere is some characteristics in most of the violence behavior of the psychotics, which may be helpful for preventing.
6.Advances in research on the association between single nucleotide polymorphisms of the DNA repair genes and resistance to platinum-based chemotherapy.
Jia WEI ; Bao-rui LIU ; Ya-ping WANG
Chinese Journal of Oncology 2006;28(3):161-163
DNA Repair
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genetics
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DNA-Binding Proteins
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genetics
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Drug Resistance, Multiple
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Drug Resistance, Neoplasm
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Endonucleases
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genetics
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Humans
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Neoplasms
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drug therapy
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genetics
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Nuclear Proteins
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genetics
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Organoplatinum Compounds
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therapeutic use
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Platinum Compounds
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therapeutic use
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Polymorphism, Single Nucleotide
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Transcription Factors
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genetics
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X-ray Repair Cross Complementing Protein 1
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Xeroderma Pigmentosum Group D Protein
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genetics
7.Effect of Local Intramuscular Repeated Injection with Botulinum Toxin-A for Treatment of Spastic Cerebral Palsy
ya-jie, WANG ; bao-qin, GAO ; wei-li, YANG
Journal of Applied Clinical Pediatrics 2004;0(08):-
Objective To observe the curative effect of botulinum toxin A(BTX-A)repeated intramuscular injection for treatment of serious spastic cerebral palsy.Methods Thirty cases with serious spastic cerebral palsy received local repeated intramuscular injection. The interval time was 3 months. The dose of BTX-A was 4 U/kg.The muscle tone was assessed with the modified ashworth scale and range of motion with physical rating scale(PRS).The indexes were evaluated before injection and 3 months after the second injection. Paired-samples t-test was used in the statistic analysis.Result The muscle tone and PRS had remarkable improvement after second therapy with BTX-A(P
10.Implementation of performance metrics in clinical trial data management.
Ya-zhong DENG ; Hong-wei WANG ; Hai-jun FU
Acta Pharmaceutica Sinica 2015;50(11):1488-1492
There is no a systemic performance metrics for clinical data management. While the CDMC in China starts to develop the quality metrics for clinical data management, it is essential to think over the performance and pursue metrics implementation of clinical data management in China. This article provides the basic concept, development and implementation of the performance metric in clinical data management.
China
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Clinical Trials as Topic
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standards
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Data Collection
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standards
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Information Storage and Retrieval
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standards