OBJECTIVE:To investigate the effect of compound glycyrrhizin(SNMC)combining artificial liver on severe hepatitis.METHODS:58patients with severe hepatitis were randomly divided into two groups,for the control group,apart from the basic treatment,each of them was also given plasmapheresis or hemoperfusion every3d～5d for5～10times ac?cording to their state of illness;For the treatment group,they were treated with SNMC apart from the therapy of the control group.RESULTS:The total effective rates of the treatment group and the control group were64.52%and40.74%,respec?tively,thus significant differences existed between the2groups(P

Despite the continued development of radiotherapy and chemotherapy,surgery is still the first choice for the treatment of colorectal cancer.Complete mesocolic excision (CME) based on anatomy and embryology,the sharp separation is carried out along the embryonic development.A large number of clinical trials have confirmed that the operation can significantly reduce the local recurrence rate and improve survival rate.The technique may become a standardized surgery for colon cancer.To learn about the research progress of the application of complete mesocolic excision,this paper collected relevant literatures of CME for reviewing.

Objective To explore the prognostic value of long-time EEG monitoring and the clinical examination index in comatose patients.Methods The long-time EEG monitoring and the modified Glasgow coma scale were done in 26 comatose patients(15 patients were male;11 patients were female;17—40 years old)in acute phase.The complexity of cerebral hemisphere was analyzed by computer.The patients were followed-up for 2 months and evaluated by Glasgow outcome scale.The correlation between the long-time EEG monitoring,clinical examination index and the prognosis of the patients was analyzed.The time- variation of hemisphere complexity and the relationship between prognosis and entropy were observed. Results The specificity(77.8%)and accuracy rate(92.3%)of long-time EEG monitoring in predicting the outcome of the acute comatose patients were higher than those of clinical examination.The EEG index appeared more closed-up with prognosis than clinical examination.The correlation coefficient between the EEG index and the modified Glasgow prognosis scoring was r=0.81(P

Objective To observe the effect of facilitation techniques of breathing combined with acupuncture on post-stroke hiccup.Methods 68 post-stroke hiccup patients were divided into 2 groups, 34 cases in each group. The observation group was treated with the facilitation techniques of breathing combined with acupuncture, while the control group was treated with acupuncture only. The two groups were evaluated on the 3rd and 7th day after treatment. Results The total efficacy was higher in the observation group than in the control group (P<0.05). Conclusion Facilitation techniques of breathing may release the post-stroke hiccup.

Objective To statistically analyze clinical research literature on acupuncture treatment of gouty arthritis, explore regularities in its point selection and provide a basis for clinical point selection and reasonable point combination.Method Gouty arthritis, acupuncture, warm needling moxibustion, electroacupuncrue and fire needling were used as key words. January 1990 to May 2014 China HowNet (CNKI) full-text database and Wanfang academic periodical full-text database were searched to retrieve, sort out and analyze clinical literature on acupuncture treatment of gouty arthritis at home and abroad. Acupoints included in the literature were sorted out. Statistical analysis was made of the categories, meridians, use frequencies and positions of selected acupoints.Result One hundred and thirty-five articles with a total of 120 acupoints were included. From the analysis of point selection, the acupoints most frequently used to treat gouty arthritis were, arranged in order, Taichong (91), Sanyinjiao (87), Zusanli (80), Yinlingquan (58), Quchi (52), Taixi (51), Yanglingquan (45), Xuehai (44), Taibai (44) and Hegu (44). From the analysis of pertaining meridians, the meridians of more frequently used acupoints were the spleen meridian of foot-taiyin (323), the stomach meridian of foot-yangming (209), the large intestine of hand-yangming (143), the liver meridian of foot-jueyin (140), the gallbladder meridian of foot-shaoyang (134), the kidney meridian of foot-shaoyin (84) and the bladder meridian of foot-taiyang (80). From the analysis of point selection from different places, the part where acupoints were most distributed was the lower limb.Conclusion For acupuncture treatment of gouty arthritis, local and along-meridian point selections are main ones, selected points are relatively scattered and often located in the lower limb, and point selection is partly combined with syndrome differentiation, which provide a clinical reference.

After a description of research contents and methods in scientific literature novelty assessment and tech-nical competitive intelligence , the necessity and feasibility to add technical competitive intelligence analysis into scientific literature novelty assessment were analyzed , followed by an elaboration on adding technical competitive in-telligence analysis into scientific literature novelty assessment in aspects of the contents , types and report of scientific literature novelty assessment in combination with case analysis , which showed that technical competitive intelligence analysis is an effective method for searching literature and writing scientific literature novelty assessment report .

Gastric cancer is the fifth most common cancer and the third leading cause of death globally .Apart from the suc-cessful phase Ⅲclinical trial of trastuzumab and Ramucirumab , other targeted therapies in gastric cancer ( GC) have fallen short or still in early clinical development .In this review, we will summarize the most up to date information on many of the potential actionabledriver genesin gastric cancer and the importance of using the optimal diagnostic test to select for these molecularly defined patients . We focus on the following aspects:HER-2, EGFR, FGFR, MET, IGF-1R and VEGF.

Objective To evaluate the efficacy and safety of ultrasound-guided percutaneous ethanol injection(PEI)in the treatment of solitary benign thyroid adenoma.Methods One hundred and twelve patients with thyroid adenoma underwent PEI.The amount of anhydrous ethanol injected was approximately one third of the volume of thyroid nodule and used once a week,the injection was repeated two to five times.Results The average volume of pure adenoma and adenoma associated with cystic degeneration is ( 4.93 ? 0.48 )cm 3 and ( 7.89 ? 0.91 )cm 3;the nodules decreased markedly to ( 3.22 ? 0.40 )cm 3 and ( 3.85 ? 0.55 )cm 3 3 months after PEI treatment (P

Utilizing disodium phenylphosphate as substrate and determining the amount of phenol set free by its reaction with red B salt, Keplan and Narahara devised a sensitive micro method for the determination of serum alkaline phosphatase. We have studied the method and found it, with a few modifications, convenient and accurate. The chief advantages of this method lie in the fact that it requires serum samples of only 0.01 ml. and a reaction time of only 30 minutes, and that the whole procedure can be completed in one test tube. In order to make the method applicable to the examination of infants and small laboratory animals, we have introduced a glass capillary method for collecting cutaneous blood and separating small amounts of serum, and a micro pipet to deliver 0.01 ml. accurately. With this method, the serum alkaline phosphatase of 55 normal adult Chinese of both sexes ranged from 0.4 to 3.0 units per cc. and averaged 1.68 units with a standard deviation of ? 0.63 units and standard error of the mean of ? 0.09 units. Parallel determinations with Bodansky's method and this method were done on a series of 46 individuals, the ratio of the unitage of serum alkaline phosphatase by Bodansky's method to that by present method was found to be on the average, approximately 2. The serum alkaline phosphatase of a small series of normal rats was found to average 15.2 units per cc. A preliminary trial with rats to ascertain the effect on serum alkaline phosphatase of rachitogenic diet and vitamin D failed to give consistent results. This aspect of the work requires further studies.

Based on previous research on the knowledge network,the paper summarizes the relevant research on the concept evolution,structure,model,evaluation index and practical application of the knowledge network based on the literature carrier,and provides reference for knowledge management and scientific innovation management.