In this article, 100 maxilla samples of the Kunming area werc takcn for observing the suborbital foramen and infraorbital canal and their relative data. The purpose of this investigation was to provide an anatomical basis for the clinical block anesthesia of the infraorbital nerve and its branches. The results show that 93％ of the suborbital foramen is an oval-shaped mono-foramen and 7％ has a paraforamen, their exact positions on the maxilla being measured. The vertical diameter of the suborbital foramen averages 5.83mm, and the transverse one 3.05ram. The average value of the vertical diameter of the infraorbital canal is 11mm, its anterior part axis toward inferior, anterior and interior. 66% of infraorbital canals can be passed through smoothly by a ~#6 hypodermic needle, 12％ with reistance and 22％ can not be passed through.

The incidence,location,shape and size of enmel pearls on l2379 extracted teeth were ob- served in this article. The results are as follow:The morbidlty of the enamel pearls is 2.49%.The most freguent morbidity is on the maxillary third molar,the second is on the mandible first molar.The freguent location is on the bifurcation of crown-cervical. The enamel pearls on maxillary molar often round and on the mandible molar are fusiform.The maximun diameter of enamel is 3.2mm,the minnimum is 0.5mm.,and its average diameter is 1.56mm. The author suggested that enmel pearls is one teind of developmental variations of tooth morphology,and it may be important influence on the pathogenesis,development,treatment and prognosis of the periodental diseases.

It is the purpose of this study to examine the prevalence and distribution of cementicles on different root surfaces of 524 extracted human teeth. The results are as follows:185 teeth had cementicles and the morbidity accouted for 35% of the sum total of investigation. Cementicles were seen on approximately over 50% of the canines and molars and fewer than 50% of the other teeth.On canines,cementicles were found most frequently in the mid- dle and apical thirds of the roots.On molars,cemwnticles were found frequently in furcations. A relationship with the presence of enamel projections at the cementenamel junction in molar furcations was noted.The findings suggested that cementicles frequent occurrance in certain locations be of grear clinical importance to periodontal diseases.

AlM: To analyze the effect of corneal limbus stem cell transplantation and amniotic membrane transplantation in treatment of recurrent pterygium with symblepharon.
METHODS:Totally 80 cases of patients with recurrent pterygium and symblepharon were randomly divided into pterygium resection combined with limbal stem cell transplantation group and pterygium excision with amniotic membrane transplantation group, 40 cases in each group. All patients were followed up for 6mo after the operation, the recurrence rate of pterygium and symblepharon were observed.
RESULTS:There were 2 cases of recurrence in the group of corneal limbus stem cell transplantation (5%), 8 cases of recurrence in the group of amniotic membrane transplantation (20%), with statistical difference between two groups (P<0. 05).
CONCLUSlON:Two kinds operation could significantly reduce the recurrence rate of recurrent pterygium, but the corneal limbus stem cell transplantation group has the lower recurrence rate.

A novel H17N10 subtype of the influenza A viruses was found in bats in 2012. Protein sequence and structural analyses revealed that the HA17 and NA10 proteins of this strain are different from corresponding ones in known influenza A subtype viruses. Both HA17 and NA10 proteins cannot bind to sialic acid,which indicates that they may have novel functions. This article briefly describes the state of current research into the H17N10 subtype of bat influenza A virus.
Animals ; Chiroptera ; virology ; Influenza A virus ; classification ; genetics ; isolation & purification ; metabolism ; Orthomyxoviridae Infections ; veterinary ; virology ; Viral Proteins ; genetics ; metabolism

BACKGROUND: Modern medicine has not completely clarified the pathogenesis of diabetic gastroparesis, and Weidong Kang may have certain efficacy.OBJECTIVE: To observe the clinical efficacy and safety of Weidong Kang on diabetic gastroparesis, and compare with the efficacy of Motilium.DESIGN: A case-controlled observation.SETTINGS: Department of Traditional Chinese Medicine, Affiliated Hospital of Chongqing Normal University; Chongqing Institute of Traditional Chinese Medicine.PARTICIPANTS: Sixty outpatients and inpatients with diabetic gastroparesis were selected from the Affiliated Hospital of Chongqing Normal University and Chongqing Institute of Traditional Chinese Medicine from April 2001 to December 2005. They were randomly divided into two groups: ① treatment group (n =30): 20 males and 10 females; 31-58 years of age, the disease courses ranged from 0.5 to 26 years; ② control group (n =30): 18 males and 12 females; 30-69 years of age, the disease courses ranged from 0.5 to 20 years. Informed contents were obtained from all the subjects.METHODS: In the treatment group, the patients were treated with oral Weidong Kang decoction, three times a day,30 mL per time; Weidong Kang decoction consisted of official magnolia bark, immature bitter orange, betel nut, rhubarb,Chinese thorowax root, largehead atractylodes rhizome, dendrobium stem, 100 mL/bottle, containing 100 mg crude drug,provided by the Department of Pharmacy, Chongqing Institute of Traditional Chinese Medicine). In the control group, the patients with treated with Motilium, three times a day, 10 mg per time. All the patients were treated for four weeks as a course. The scores of dyspeptic symptoms and the time of gastric semi-emptying of liquid (T/2) were observed, the efficacy, the score of quality of life (QOL) and safety were evaluated before and after treatment.MAIN OUTCOME MEASURES: Scores of dyspeptic symptoms; Time of gastric semi-emptying of liquid (T/2); Evaluation of efficacy; score of QOL; Safety.RESULTS: All the 60 patients with diabetic gastroparesis were involved in the analysis of results. ① Amelioration of dyspeptic symptoms: After treatment, the scores of dyspeptic symptoms an total score were all obviously lower than those before treatment in both groups (P ＜ 0.01), the scores of epigastric satiety, nausea and vomiting, decreased appetite and epigastric pain in the treatment group were all obviously lower than those in the control group (P ＜ 0.05-0.01). ② Clinical efficacy: The total effective rate in the treatment group was obviously higher than that in the control group [90.0% (27/30); 73.3% (22/30), P ＜ 0.05]. ③ Time of gastric semi-emptying of liquid (T/2): In the treatment group,it was obviously ameliorated after treatment as compared with that before treatment (P ＜ 0.01). ④ Amelioration of QOL by symptom frequency-36 health survey (SF-36): In the treatment group, the scores of general health, somatic pain,vigor and mental health after treatment were obviously higher than those before treatment (P ＜ 0.05). In the control group, the scores of general health and mental health after treatment were obviously higher than those before treatment (P ＜ 0.05). ⑤ Evaluation of safety: In the treatment, there were no obvious differences in the blood and urine routine examinations, liver function and kidney function before and after treatment (P ＞ 0.05).CONCLUSION: Weidong Kang is an effective and safe drug for alleviating dyspeptic symptoms in patients with diabetic gastroparesis.

Objective The changing patterns of pathogenic isolates and antibiotic susceptibility in Chongqing's neonates between 2010 and 2015 were investigated for the purpose to provide evidence for rational use of antibiotics and control of nosocomial infections.Methods The distribution of pathogenic bacteria and antibiotic susceptibility were analyzed.Identification and antibiotic susceptibility testing were carried out using BD Phoenix 100 automated system and the conventional Kirby-Bauer method.The results were interpreted in accordance with the breakpoints of the Clinical and Laboratory Standards Institute.Results A total of 10 569 pathogenic bacterial strains were isolated during the period,most of which were gram-negative bacteria (80.8 ％,8 540/10 569),primarily Klebsiella pneumoniae (29.3 ％),followed by Escherichia coli (16.7 ％),Acinetobacter baumanmii (9.9 ％),Enterobacter cloacae (8.6 ％) and Pseudornonas aeruginosa (3.3 ％).Gram-positive strains accounted for 14.1％ (1 490/10 569),mainly Staphylococcus aureus (7.8％),Staphylococcus epidermidis (2.2 ％),and Staphylococcus haemolyticus (1.8 ％).Imipenem and meropenem showed high activity against Enterobacteriaceae (＜ 10％ resistant),followed by P.aeruginosa (＞ 10 ％ resistant),and A.baumannii (＞20％ resistant).The prevalence of carbapenem-resistant strains was 8,4 ％ in K.pneumoniae and 2.9 ％ in E.coli isolates,No gram-positive isolates were resistant to vancomycin,teicoplanin or linezolid.Conclusions K.pneumoniae was the most frequently isolated pathogen in the neonates treated in Children's Hospital of Chongqing Medical University.The prevalence of A.baumannii isolates is increasing.Carbapenem-resistant Enterobacteriaceae strains are emerging.

Health resources allocation, the cornerstone of health production capability, includes effective allocation of increments and rational readjustment of stocks. Using the least square method and variance analysis, the authors created a multilinear regression model on the basis of the calculation method and analysis principle of the Cobb-Douglas production function and in light of historical data in China's health sector and made a positive analysis of the current state of health resources allocation in China The result indicates that the input in health human resources has been insufficient and their contribution to production has been on the moderate side. Moreover, health resources allocation has shown decreasing return to scale on the whole.

Intraperitoneal. injection of the essential oils of Asarum himalaicum and A. heterotropides var. mand shuricum can inhibit the proliferation of granuloma induced by implantation of cotton pellets in rats, and change the distribution of Copper and Zinc,the two necessary trace elements for rats,in rat serum and liver.They reduce concentration of Zinc but increase that of Copper in the serum,while elevate the concentration of Zinc but reduce that of Copper in liver. The oil of A. himalaicum collected from Ningxia Region showed even stronger effects.

Objective:To prepare nevirapine nanosuspensions ( Nev-NS) and study the pharmacokinetics in rats. Methods:Nev-NS was prepared by a high pressure homogenization technology. The particle size, PDI and Zeta potential of the nanosuspensions were used as the indices to determine the influencing factors in the preparation process. Nevirapine plasma concentration was detected by HPLC and the pharmacokinetic parameters were calculated by 3P97 software. Results: The particle size, PDI and Zeta potential of Nev-NS was (456. 1 ± 72. 1) nm, 0. 441 ± 0. 072 and ( -24. 4 ± 4. 7) mV, respectively. AUC0-12 of Nev and Nev-NS was (7. 57 ± 0.52) and (11.72 ±1.83) mg·h·L-1, t1/2 was (2.45 ±0.31) and (3.16 ±0.39) h, Tmax was (1.43 ±0.38) and (1.61 ± 0. 32) h and Cmax was (1. 62 ± 0. 42) and (3. 15 ± 0. 52) mg·L-1 , respectively. Conclusion:Nev-NS can improve the pharmacoki-netic behavior of Nev in rats significantly, and obviously enhance the bioavailability when compared with nevirapine suspensions.