1.Design and Realization of Blood Collection Information System
Chinese Medical Equipment Journal 2003;0(11):-
Objective To solve the problem of continuous augmentation of blood drawing quantity along with the increases of examination item, as well as the problem that patient identifies the lab test with difficulty because of the doctor's handwriting is always illegible. Methods The author introduced data -base management for information technology to increase structured data information and reasonably prepare the process structure. Results The implementation can avoid the repetition of blood drawing, reduce the blood using quantity and the painfulness of patient, and it also provides the standard printing lab test report, as well as the information of the blood drawing time and report taking time. Conclusion The technical improvement of the out -patient blood information system realizes the blood sample sharing and blood quantity reduction, facilitates the patient and blood drawing operator.
2.Status and challenge of vaccine research for Clostridiodes difficile in clinical trials
Chinese Journal of Biologicals 2023;36(9):1138-1142
Clostridiodes difficile(C.difficile)is the most common causative agent of antibiotic-associated diarrhea(ADD)in the world. In recent years,with the emergence of highly resistant and virulent strains,the outbreaks of C.difficile infection have occurred around the world. The incidence,recurrence and mortality of C.difficile infection are on the rise worldwide,and bring great challenges to clinical treatment. Pathogenic strains mainly produce two homologous glycosylation toxins A and B,which can cause symptoms ranging from diarrhea to highly lethal toxic megacolon. In view of the malignant consequences caused by C.difficile infection,disease prevention is still an important way worth exploring. Until now there is no approved vaccine against C.difficile. Therefore,this review assessed the status and challenge of clinical trials of vaccine research for C.difficile.
3.Rehabilitation of Perimenopausal Women with Stress Urinary Incontinence
Chinese Journal of Rehabilitation Theory and Practice 2010;16(6):584-586
ObjectiveTo study the rehabilitation for perimenopausal women with stress urinary incontinence.Methods60 perim enopausal women with stress urinary incontinence were randomly divided into groups A, B and C, 20 cases in each group. Group A for pelvic floor exercises, or Kegel training; group B received estrogen in addition; group C received low-frequency electrical stimulation and biofeedback in addition.ResultsUrinary incontinence volume and Kupperman score was positively correlated(r=0.752, P<0.01). Kupperman scores in groups A, B and C were significantly lower(P<0.01) 1 month, 3 months after treatment than before treatment. There was no statistical difference between group A and Group B at 1 month after treatment. Kupperman scores in Group C was significantly lower(P<0.01), and reduced further 3 months after treatment(P<0.01). The amount of urinary incontinence in groups A, B and C were significantly lower 1 month, 3 months after treatment than before treatment(P<0.01). There was no significant difference in urinary volume between group A and group B 1 month and 3 months (P>0.05). The urinary incontinence was significantly lower between group C and groups A, B 1 month, 3 months after treatment (P<0.01).ConclusionThe pelvic floor exercise, low-frequency electrical stimulation and biofeedback therapy can significantly reduce perimenopausal symptoms of stress urinary incontinence.
4.Approach to the patients with polycystic ovary syndrome
Chinese Journal of Endocrinology and Metabolism 2017;33(4):341-346
Polycystic ovary syndrome (PCOS)is the most common cause of anovulatory infertility in women of reproductive age, exerting significant impacts on glucose and lipid metabolism, cardiovascular and endometrial deseases, as well as breast, skin, bone, and psychology fields. As a complex, multi-system of endocrine and metabolic disease, PCOS would be recognized as a component of metabolic syndrome in an overall consideration. The clinical treatment of PCOS is expected to turn simply regulating menstruation and ovulation adjustment into the combination of insulin resistance improvement with antihyperandrogen and ovulation treatment comprehensively.
5.Progress of adiponectin in reproduction and fertility
Chinese Journal of Endocrinology and Metabolism 2012;28(4):347-350
There is a strong support for a role played by adiponectin in the function of ovary and placenta.There is evidence of direct effects of adiponectin on the late stages of folliculogenesis,and additive interactions of adiponectin with insulin and gonadotropins in inducing periovulatory changes in ovarian follicles.Adiponectin has demonstrated a potential effect on ovarian function as well as a possible effect on the formation of placenta,via multiple mechanisms,providing new strategies for the etiology investigation,prevention and treatment of reproductive and related metabolic diseases.
6.The research of the effect of anti-oxidation, anti-athletic fatigue, anti-oxidative damage to nerve cells of mixed natural antioxidant.
Chinese Journal of Applied Physiology 2010;26(1):27-85
Animals
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Antioxidants
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pharmacology
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Cerebellum
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cytology
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Dietary Supplements
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Drugs, Chinese Herbal
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chemistry
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Fruit
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chemistry
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Male
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Muscle Fatigue
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drug effects
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Neurons
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drug effects
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pathology
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Oxidative Stress
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drug effects
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Physical Exertion
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Rats
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Rats, Wistar
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Vegetables
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chemistry
7.Implantation of intrathecal infusion system for intractable pain therapy
Basic & Clinical Medicine 2006;0(11):-
Objective To discuss the mechanism,procedures and effect of implantable intrathecal infusion system for intractable pain therapy. Methods Among the 4 patients with intractable pain,2 had cancer pain,2 had failed back syndrome.Before operation,Visual Analogy Scale(VAS) were 8~10.Three had bolus intrathecal injection screening trial,1 had bolus epidural injection screening trial.In the clinical trail,VAS all decreased to 75%~90%.(Results) They all had intrathecal infusion system implantation.After operation,Morphine was prescribed(intrathecally.) The dose was 1~(8 mg).They all had satisfied pain relief without serious drug adverse effects.Conclusion The effect of implantable intrathecal system for intractable pain was satisfied.The drug adverse effects were obviously alleviated.
8.Modern neurosurgical management of chronic pain
Basic & Clinical Medicine 2006;0(11):-
The treatment of chronic pain needs multidisciplinary management.Neurosurgical procedures hold an important role.With advancement in stereotactics,microsurgical and electrophysiological techniques,neurosurgical treatment becomes microinvasive,safer and popular.Neurosurgical procedures include anatomic,neuroaugmentative and neuroablative therapies.The procedure should be chosen individually.The pain characters,primary disorders,quality of life and survival time of the patient should be considered.A successful management must be well-indicated.
9.Survey and countermeasures of anxiety induced by acute trauma
Journal of Third Military Medical University 2002;0(12):-
Objective To understand the mental health, especially the anxiety of patients suffering from acute trauma in order to adapt the patients to the situation of acute trauma and cope with acute trauma better in physiological and psychological health. Methods Questionnaire designed by means of Symptom Checklist 90(SCL 90) and Self rating Anxiety Scale(SAS) was used to survey the stress response of the patients to anxiety induced by acute trauma. Results The parameters in SCL 90 of acute trauma patients were significantly higher than those of the normal control( P
10.Relation between angiotensin Ⅱ and its inhibitor to human renal interstitial fibroblast
Chinese Journal of Practical Internal Medicine 2001;0(05):-
Objective To observe the relationship between fibroblast and angiotensin Ⅱ and,the influence of angiotensin Ⅱ on human renal interstitial fibroblast(HRIF).Methods Separated and cultured renal interstitial fibroblasts were identified and the 3H-TDR incorporation,flow cytometry and immunohistochemical technique were applied to observe the effect of angiotensin Ⅱ on the cell cycle and DNA synthesis of HRIF and the inhibitive effect of Losartan.Results Angiotensin Ⅱ (10 -10M-10 -6M) had elevated the incorporation rate of HRIF 3H-TDR and had showed dose-dependence in day 1 and day 3(? 1=0.709,P