1.Comparative study of CT,MRI images and pathological findings of ganglioneuroma
Chinese Journal of Primary Medicine and Pharmacy 2014;(15):2257-2258
Objective To study the CT and MRI findings of ganglioneuroma and compare with pathology . Methods Clinical data of 12 patients with ganglioneuroma confirmed by surgical pathology were retrospectively ana -lyzed.All patients underwent CT and MRI , and the results were compared with pathological results .Results The average size of the lesion was (4.7 ±1.2)cm,CT scan was uneven or uniform density.In MRI plain scan,T1WI showed heterogeneous low signal ,T2 WI showed uneven contour signal ,the middle part of the strip of low signal .12 cases received enhanced MRI scan ,there were four cases of non-enhanced,mild enhancement in 3 cases,uniformity progres-sive strength enhanced with two cases ,uneven progressive enhancement in 3 cases,there was 1 patient with edge of the annular reinforcing ,in accordance with CT scan results .Conclusion When CT and MRI used as the detection means of ganglioneuroma ,its performance has a certain characteristic ,and that reflects in large part the tumor shape ,size and tis-sue composition .And pathological tumor is rich in a lot of mucus matrix has a certain relationship .
2.Perioperative Utilization of Antibacterial Drugs in Patients Undergoing Modified Radical Mastectomy
China Pharmacy 2005;0(17):-
OBJECTIVE:To evaluate the perioperative utilization of antibacterial drugs in patients undergoing modified radical mastectomy. METHODS: In this retrospective study, the perioperative utilization of antibacterial drugs in patients who underwent modified radical mastectomy during 2006 and 2006 were analyzed statistically. RESULTS: 100% of the patients received antibacterial drugs preventively. The problems involved in the preventive use of antibacterials manifested as medication without indications, irrational application of broad-spectrum antibacterials, frequent change of drugs, blind drug combination, inappropriate time of initial administration and prolonged drug use etc. CONCLUSION: The perioperative use of antibacterial drugs in patients undergoing modified radical mastectomy in our hospital is far from rational. The Clinicians' medication behavior should be standardized and supervision on rational drug use should be strengthened.
3.Allergic Reactions Induced by Aminoglycosides: Literature Analysis of 98 Cases
China Pharmacy 2005;0(20):-
OBJECTIVE: To discuss the clinical characteristics and the patterns of allergic reaction(ADR) caused by aminoglycosides.METHODS: 98 ADR cases induced by aminoglycosides were retrieved from domestic journals reported from Jan.1990 to June 2007 for a statistical analysis.RESULTS: The ADR of aminoglycosides was closely related to route of administration,unreasonable application,allergic history,etc.CONCLUSION: The ADR of aminoglycosides and rational use of aminoglycosides should be strengthened further in the clinical practice.
5.Treatments and Rehabilitation for Progressive Supranuclear Palsy (review)
Chinese Journal of Rehabilitation Theory and Practice 2017;23(2):173-178
Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease. The etiology and pathogenesis are still unclear. Nowadays there is a lack of an effective molecular marker which can effectively assist the early diagnosis and prognosis of this disease. This article reviewed the pathological anatomy, diagnostic criteria, subtypes and clinical manifestations, imaging studies, scales evaluation, treat-ment and rehabilitation, complications and risk factors of PSP. Patients with PSP should be managed by a multidisciplinary team. The man-agement of PSP should include the rehabilitation of disorder and palliative treatment, as well as support and education, to improve the quali-ty of life for patients and their caregivers.
6.Bundle treatments for patients with pulmonary tuberculosis and respiratory failure
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2015;22(3):291-294
Objective To investigate the therapeutic effect of bundle treatments for critically ill patients with pulmonary tuberculosis and respiratory failure (RF).Methods A prospective study was conducted, including 56 patients with pulmonary tuberculosis and RF necessary for invasive mechanical ventilation admitted into Department of Critical Care Medicine of the Fourth People's Hospital of Nanning City from January 2013 to December 2014 as the observation group to be treated by bundle treatments. A series of treatments and cares were given to the critically ill patients, such as invasive mechanical ventilation, application of antibiotics by experience within the first hour, supportive treatment targeted to hemodynamics in early stage, correction of brain dysfunction, effective therapy for tuberculosis, establishment of enteral nutrition in early stage and prevention of ventilator-associated pneumonia (VAP), etc. All the above treatments were completed one by one in 6 hours to 12 hours. Meanwhile, 42 patients who hospitalized from January 2011 to December 2012 and treated with conventional targeted therapy were designed as the control group. The changes of vital signs, blood routine test, respiration, liver, kidney, etc organ functions, the improvement of acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) score, expected mortality and sequential organ failure assessment (SOFA) score, the incidence of VAP, cure and improvement rate, mortality, duration of invasive mechanical ventilation, the length of stay in intensive care unit (ICU) were compared between the two groups after treatments.Results There were no statistically significant differences in the comparisons between the two groups before and after treatments in temperature, white blood cell count (WBC), blood glucose, total bilirubin (TBil), alanine transaminase (ALT), albumin (Alb) and cholesterol level (allP > 0.05), except the platelet (PLT) count in observation group was higher than that in control group before treatments. After treatments for 72 hours, in the two groups, the heart rate (HR), respiration rate (RR), APACHE Ⅱ score and expected mortality were lower than those before treatments, while the arterial partial pressure of oxygen (PaO2) and oxygenation index were higher than those before treatments. There were no statistically significant differences in pH value, PLT, arterial partial pressure of carbon dioxide (PaCO2) and SOFA score before and after treatments in the control group (allP > 0.05). In the observation group, after treatments, the pH value was increased compared with that before treatments, while PLT, PaCO2 and SOFA score were decreased compared with those before treatments (allP < 0.05). The degrees of improvement of PaCO2 and oxygenation index in the observation group were superior to those in the control group [PaCO2 (mmHg, 1 mmHg = 0.133 kPa): 43.32±9.10 vs. 56.10±9.39, oxygenation index (mmHg): 330.60±100.98 vs. 245.65±83.20, bothP < 0.05]. After bundle treatments, compared with control group, the incidence of VAP was decreased [16.07% (9/56) vs. 33.33% (14/42),P < 0.05], improvement and cure rate was increased [78.57% (44/56) vs. 59.52% (25/42),P < 0.05] and mortality was decreased significantly in observation group [10.71% (6/56) vs. 28.57% (12/42),P < 0.05]. The duration of invasive mechanical ventilation (days: 9.15±3.59 vs. 16.96±13.44) and the length of stay in ICU (days: 13.30±4.24 vs. 23.00±15.03) in the observation group were shorter than those in the control group, but no statistically significant differences were found (bothP > 0.05).Conclusion The bundle treatments can effectively reduce the incidence of VAP and elevate the improvement and cure rate in patients with pulmonary tuberculosis complicated with RF.
8.On the construction of college English curriculum in medical colleges and universities under IT environment
Chinese Journal of Medical Education Research 2012;11(7):747-749
Based on the discussion of the present English teaching in medical colleges and universities in China,this paper clarifies the mission and task of English teaching in medical colleges and universities and proposes that medical colleges and universities should attach importance to the education goals and needs of the department,major and students in the information age.It is believed that a scientific,reasonable and perfect English curriculum can be achieved by integrating IT into English curriculum,applying individualized teaching mode and expanding course connotation.
9.Legal issues on organ donor rescission prior to organ removal from the body
Chinese Journal of Hospital Administration 2013;29(9):669-671
Encouraging voluntary donation of citizens' organ is the best institutional solution for the severe shortage of organ transplantation.The policy incentives should allow donors to rescind their donation of their organ anytime before the organ is removed from their body.As long as the donor does not commit subjective offence,he/she shall be released from any legal responsibilities.This arrangement is highly significant legally and practically.
10.The preliminary study of the effect of ritodrine on the change of heart rate in threatened premature labor.
Chinese Journal of Practical Gynecology and Obstetrics 2001;17(4):228-230
Objective To determine the change of maternal heart rate during the treatment with ritodrine for threatened premature labor. Methods110 cases of threatened premature labor were chosen. The ritodrine 100mg in 5% G. S 500mL was intravenously administered. The initial dosage was 6 drops/min, and the dose was increased until uterine contractions were inhibited. The treatment lasted for 40 to 48 hours after the uterine contractions were inhibited, then the oral tablets was recommended. If necessary, repeated treatment was given to some patients. The maternal heart rate was recorded in the whole process of treatment and was compared with the dosage administered. The labor time, fetal weight and Apgar′s score were also analyzed. Results The maternal basic heart rate was increased at first and then decreased. The increasing significantly increased( P < 0.01 ) when the uterine contraction was inhibited. , but no difference showed among the groups of different gestational age( P>0.05 ). The maternal heart rate was increased with the increasing of ritodrine( max. 140/min). labor time was significantly prolonged with the treatment of ritodrine( P<0.01 ) ,while that of the idiopathic premature labor was prolonged most obviously ( P < 0.05 ). Average fetal weight was (2.42 ± 0.49) kg, and the average Apgar′s score was≥8. Conclusion In the treatment of inhibiting uterine contractions,the increasing of maternal heart rate caused by ritodrine can be used as an indicator of therapeutic effect.