1.Clinical Observation on Primary Infantile Tonic-Clonic Epilepsy Manifested as Syndrome of Convulsion due to Phlegm-Heat Treated by Xiaoer Dingfeng Decoction
Rong MA ; Ping RONG ; Xiao-Wei WEI ;
Journal of Traditional Chinese Medicine 1993;0(05):-
Objective To observe the effectiveness and salty of Xiaoer Dingfeng Decoction(Decoction to stop wind in children con- vulsion)in the treatment of syndrome of primary infantile convulsion due to phlegm-heat in tonic-clonic epilepsy.Methods Totally 90 infantile patients were randomized into three groups,which were treated by Xiaoer Dingfeng Decoction,Kangxian(Capsule to treat epilepsy)and Xifeng Capsule(Capsule to calm the wind)respectively.Frequency of seizure,lasting duration,and change of electroen- cephalogram(EEG)were observed 12 months later.Results The total effective rate of Xiaoer Dingfeng Decoction group was 86. 67%,better that that of Kangxian Capsule group(P0.05). It could greatly reduce the frequency of seizure,shorten the lasting duration,and improve the EEG.Conclusion Xiaoer Dingfeng De- coctions is effective and safe for the syndrome of primary infantile convulsion due to phlegm-heat in tonic-clonic epilepsy.
2.Study of cognitive tendencies in recognizing negative emotional faces
Pingping MA ; Yifang WANG ; Ping WEI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(2):157-159
Objective To study the cognitive tendencies in recognizing negative emotional faces.Methods The experiment used the traditional flanker paradigm for reference.Forty-eight university students (19 males,29 females) finished the flanker tasks deigned by E-Prime, and their accuracy rate and reaction time were recorded in the study.Results ANOVA revealed that,in all cases,the accuracy rate of anger was significant higher than fear and sadness (96.60% ,94.50% ,94.40% ) (P<0.05).And when the flanking stimuli were fear faces or there were no flanking stimuli, the reaction time of anger was much shorter than fear and sadness ( respectively,fear(801.27 ± 140.99) ms,anger(723.94 ± 151.37 ) ms, sadness(812.21 ± 148.85 ) ms; fear(788.17 ±148.81 ) ms, anger ( 694.28 ± 111.99 ) ms, sadness (763.57 ± 133.91 ) ms, P < 0.05 ).When the flanking stimuli were anger or sadness faces, the reaction time of anger was significant shorter than fear( respectively, fear( 824.09 ± 164.42) ms, anger (721.48 ± 124.06 ) ms, sadness ( 760.50 ± 131.12 ) ms; fear ( 798.95 ± 146.40) ms, anger (702.55 ± 136.07 ) ms, sadness (750.48 ± 133.86) ms, P < 0.05).Conclusion There are no flanker effects in recognizing different negative emotional faces, but there are anger superiority effects of face recognition and cognitive tendencies, which is helpful for clinical diagnosis and treatment of some diseases associated with emotional disorders.
3.Protection of Patients' Privacy in the Application of E-Medical Record
Wei MA ; Xueguo XV ; Ping YANG
Chinese Medical Ethics 1994;0(05):-
As the application of e-medical record in clinical practice,patients' privacy has been challenged due to the unsafe factors in programming system,administration and usage of records,and data share of network,etc.The paper comes up some countermeasures to protect patients' privacy including refining technological specification of the formation,storage,and utilization of e-medical records,reducing program flaws and hidden dangers,and enhancing e-medical record users' legal consciousness and patients' consciousness of self-protection,in order to protect the patients' privacy and promote the healthy development of e-medical record.
4.Immunohistochemical study of the expression of BMP,IL- 1,IL- 6,TNF-? in congenital pseudarthrosis of tibia
Chinese Journal of Orthopaedics 2000;0(02):-
0.05). The expression of IL- 1, IL- 6, TNF-? in fibromatosis and the periosteum of CPT was higher than that in normal periosteum and traumatic pseudarthrosis (P
5.Correlation between lacunar cerebral infarction and serum uric acid level in elderly male hypertension patients.
Lei JIANG ; Ling CHENG ; Wei-Ping WU ; Qiang MA ; Wei-Ping GUAN
Chinese Journal of Applied Physiology 2014;30(4):357-359
OBJECTIVETo study the correlation between lacunar cerebral infarction and level of serum uric acid in elderly male hypertension patients.
METHODSNinety-eight elderly male hypertension patients were enrolled in this study. They all underwent cerebral magnetic resonance imaging (MRI) scan, and their clinical and laboratory data were collected. The patients were divided into the 1st group (n = 32), the 2nd group (n = 32) and the 3rd group (n = 34) according to the level of serum uric acid.
RESULTSThe numbers of lacuner infarction, serum creatinine, urea and high density lipoprotein(HDL) were significantly diferrent from the other groups. The numbers of lacuner infarction were positively related with serum uric acid and urea. Multiple variant analysis showed that serum uric acid was the independent factor of the numbers of lacuner infarction.
CONCLUSIONThe elevated level of serum uric acid may contribute to the risk factors of lacuner infarction.
Aged, 80 and over ; Cerebral Infarction ; etiology ; Humans ; Hypertension ; blood ; complications ; Male ; Regression Analysis ; Risk Factors ; Uric Acid ; blood
6.Microbial transformation of buflomedil by Cunninghamella blakesleana AS 3.153.
Wei WANG ; Yanan YANG ; Xiaomin MA ; Ping BU ; Lu SUN
Acta Pharmaceutica Sinica 2012;47(7):934-40
The microbial transformation of buflomedil by Cunninghamella blakesleana AS 3.153 was studied, as well as a microbial model which can be used to mimic metabolism of buflomedil in mammal was established. Experiments were conducted to screen the capabilities of four strains of Cunninghamella species to transform buflomedil, in which C. blakesleana AS 3.153 was selected for a preparative biotransformation. Furthermore, the microbial model was established based on the transformation condition optimization. The parent drug and its metabolites produced by C. blakesleana AS 3.153 were detected by liquid chromatography-mass spectrometry method and three metabolites were identified while two of them were new found metabolites. Two major metabolites, para-O-desmethyl buflomedil and 12-C-oxidated buflomedil, were isolated by semi-preparative HPLC. Based on the comparison between different species, the microbial transformation of buflomedil by C. blakesleana AS 3.153 is more similar to the metabolism of buflomedil in human and Beagle dog than that in rat.
7.Ruptured Achilles tendon repaired with hernia repair materials using a wrap method
Junping XU ; Ping GUAN ; Dongping SUN ; Jiangrun SONG ; Wei MA
Chinese Journal of Tissue Engineering Research 2014;(25):4084-4089
BACKGROUND:The incidence of complications folowing conventional repairing for the ruptured tendon is up to 73%, such as delayed healing, adhesion, secondary rupture. These complications severely affect ankle joint function of the patients. OBJECTIVE:To reduce the complications folowing the repair and investigate the role of hernia repair materials in the repairing of ruptured Achiles tendon. METHODS:Eleven patients who underwent repair of ruptured Achiles tendon were retrospectively studied. Among them there were eight males and three females with the mean age of 42 years (26-58 years). Three cases were injured in left side and eight cases were in right side; four cases were open injury by sickle-induced damage and seven cases were closed injury by exercise-induced damage. The hernia repair materials after pruning was applied with a “wrap” method to strengthen the anastomosis repair of Achiles tendon after the conventional repair surgery had been completed. At the time of folow-up, al patients were observed for postoperative local appearance and function recovery, and assessed with Arner Lindholm standards. RESULTS AND CONCLUSION:The folow-up interval was 6-45 months (average 24.5 months). Two cases were lost to folow-up. According to the Arner Lindholm standards, the effects were excelent in seven cases (78%) and good in two cases (22%). Local appearance and function recovered wel postoperatively, and no complications occurred such as wound infection, secondary rupture and so on. A “wrap” method with hernia repair materials is suggested to strengthen the anastomosis repair of ruptured Achiles tendon after the conventional repair surgery is completed, it can significantly promote the healing of Achiles tendon ruptured end anastomosis, prevent Achiles tendon recurrent ruptures, local adhesion and infection.
8.Clinical Study on Acupuncture for Post-stroke Myodystonia
Zuowei LI ; Ping LI ; Lulu YAO ; Yingyan LI ; Wei MA
Shanghai Journal of Acupuncture and Moxibustion 2015;(7):615-617
Objective To observe the clinical efficacy of acupuncture plus contralateral needling in treating post-stoke myodystonia. Method Totally 120 patients with post-stroke myodystonia were randomized into group A, B, C and D, 30 in each group. Group A was intervened by yin-reducing and yang-tonifying needling method plus contralateral needling; group B was by ordinary acupuncture plus contralateral needling, group C was by yin-reducing and yang-tonifying needling alone, while group D by ordinary acupuncture. Clinical Spasticity Index (CSI) was observed before and after intervention. Result After treatment, the CSI scores (tendon reflex, muscle tension, episodic spasm scores and total score) were significantly changed in the four groups (P<0.01, P<0.05). The tendon reflex score, muscle tension score and total score in group A were significantly different from that in the other three groups after intervention (P<0.01,P<0.05). There was a significant difference in comparing the episodic spasm score between group A and D after intervention (P<0.01). There were significant differences in comparing the tendon reflex score, muscle tension score and total score between group B and D after intervention (P<0.05). The total score in group C was markedly different from that in group D after intervention (P<0.05). Conclusion Yin-reducing and yang-tonifying needling method plus contralateral needling is an effective method in treating post-stroke myodystonia.
9.Current status of prevention and management of radiation-induced xerostomia.
Dong-yang MA ; Wei-liu QIU ; Chen-ping ZHANG
Chinese Journal of Stomatology 2010;45(2):121-123
Amifostine
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therapeutic use
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Animals
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Head and Neck Neoplasms
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radiotherapy
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Humans
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Oral Health
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Radiation Injuries
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etiology
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prevention & control
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therapy
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Radiation-Protective Agents
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therapeutic use
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Radiotherapy
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adverse effects
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Radiotherapy, Conformal
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Salivary Glands
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radiation effects
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Salivation
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radiation effects
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Submandibular Gland
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surgery
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transplantation
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Xerostomia
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etiology
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prevention & control
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therapy
10.Relationship between therapeutic effects of ~(89)SrCl_2 on osteodynia induced by multiple bone metastases and ET,CGRP,TXB_2 and 6-K-PGF_(1a)
Wenwei SUN ; Liqin WEI ; Ping TAN ; Qingjie MA
Journal of Jilin University(Medicine Edition) 2006;0(03):-
Objective To explore the relationship between therapeutic effects of 89SrCl2 on osteodynia induced by multiple bone metastasis and ET,CGRP,TXB2 and 6-K-PGF1a.Methods 89SrCl2 treatment was used in 39 cases of multiple bone metastasis,the serum content of ET,CGRP,TXB2 and 6-K-PGF1a were detected with radioimmunological method pre-treatment and 1,3,6 months post-treatment,respectively;the ET/CGRP value was calculated.Results The content of ET showed no obvious changes 1 month post-treatment compared with pre-treatment.However,the ET contents increased significantly 3 and 6 months post-treatment compared with 1 month post-treatment and before treatment(P