3.Alzheimer's disease and sleep disorders
Rongyan ZHU ; Peng GUO ; Wei ZHANG
Chinese Journal of Geriatrics 2017;36(1):1-4
5.Clinical application of nuclear medicine imaging in amyotrophic lateral sclerosis
Peng FU ; Lingge WEI ; Ainan GUO
Chinese Journal of Nuclear Medicine and Molecular Imaging 2014;34(3):253-256
Amyotrophic lateral sclerosis (ALS),a neurodegenerative disorder,is subtle in disease onset,difficult to diagnose,and fast-growing at progression.There.are at present little specific neurological imaging characteristics of ALS.Functional brain imaging techniques,such as SPECT and PET,were the early tools for investigation of ALS.The application of pixel-based analysis software (such as SPM) renders research in this area more convenient and objective.In recent years,improvement in brain receptor PET imaging has demonstrated its important value in the early diagnosis of ALS and evaluation of cognitive impairment.
6.Study on efficacy of Chinese herbal drugs on improving endometrial receptivity detected by using trans-vaginal three-dimensional color Doppler ultrasound in patients with thin endometrium
Hong HU ; Xiuying YE ; Yiman FU ; Wei WEI ; Peng GUO
Chongqing Medicine 2017;46(19):2635-2637
Objective To explore the clinical value of transvaginal three-dimensional color Doppler ultrasound in assessing effects of Chinese herbal drugs on improving endometrial receptivity in patients with thin endometrium.Methods A total of 76 cases of patients diagnosed with thin endometrium in Jiangbei District Hospital of Traditional Chinese Medicine from June 2015 to October 2016 were selected and treated with Chinese herbal prescription for three months.The endometrial thickness,endometrial volume and blood flow indexes before and after treatment were measured by using transvaginal three-dimensional color Doppler ultrasound.Results After 3 months treatment,the endometrial thickness and endometrial volume were increased,and the pulse index (PI) and resistance index (RI) of endometrial blood flow were decreased,compared with those before treatment,there were statistically significant differences(P<0.05).The results of three-dimensional color Doppler ultrasound indicates that after 3 months treatment the vascularization index (VI),flow index (FI) and vascularization flow index (VFI) were significantly higher than those before treatment,there were statistically significant differences (P<0.05).Conclusion The Chinese herbal prescription could increase the thickness and volume of endometrium,augment blood supply,and improve endometrial receptivity significantly.Transvaginal color three-dimensional Doppler ultrasound is a convenient and objective method for evaluating clinical efficacy of Chinese herbal prescription in patients with thin endometrium,which has high practical value.
7.Preparation and anti-bacterial tests of silver-modified titanium surface.
Juan LIAO ; Wei FEI ; Jun GUO ; Peng LI
West China Journal of Stomatology 2014;32(3):303-305
OBJECTIVETo deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. To reduce the incidence of peri-implantitis, and improve the success rate of implantation.
METHODSA silver nanoparticle-modified titanium (Ti-nAg) surface was prepared using silanization method, and its surface was characterized by using X-ray photoelectron spectroscopy (XPS) and energy dispersive X-ray spectrometer (EDX). Two species of bacteria, namely, Staphylococcus aureus and Escherichia coli, were used to test the antibacterial effect of Ti-nAg surface.
RESULTSScanning electron microscope (SEM) revealed that a small quantity of silver nanoparticles were deposited on the titanium surface. XPS analyses revealed that 6.8% of silver was present on the titanium surface. After 24 h of incubation, 94.23% of Staphylococcus aureus and 95.34% of Escherichia coli were killed on the Ti-nAg surface.
CONCLUSIONResults suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.
Anti-Bacterial Agents ; Bacteria ; Dental Implants ; Escherichia coli ; Prostheses and Implants ; Silver ; Staphylococcus aureus ; Titanium
8.The optimal power of experimental endoscopic ultrasonography-guided pancreas radiofrequency ablation therapy
Wei XU ; Yan LIU ; Peng PAN ; Yan GUO ; Zhaoshen LI
Chinese Journal of Digestive Endoscopy 2014;31(3):152-154
Objective To explore the optimal power of experimental pancreatic endoscopic ultrasonography (EUS)-guided radiofrequency ablation (RFA) therapy.Methods Six healthy live minipigs were randomly divided into two groups according to random number table,which received RFA under EUS or in laparotomy.Each pig in each group was randomly allocated to received RFA at different power (5 W,10 W,15 W).The impedance was monitored and the time for each therapy was recorded.The width diameter of coagulation necrosis from RFA was measured by EUS and gross pathology.Results RFA was completed in all pigs smoothly with stable life signs and without complications.Gross and micro pathologic observation confirmed formation of coagulation necrosis lesions.The width diameter of lesions from EUS-RFA was similar to that from surgery RFA,both having a maximum value at 10 W power (11 nun VS 10 mm).Conclusion The optimal power of experimental pancreatic EUS-RFA in pig is 10W,which should be further explored for the clinical purpose.
9.Antibacterial Activity of Compounds from Rabdosia rubescens
Gaoshen LI ; Wei ZHANG ; Tao PENG ; Meizhen GUO
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(3):610-613
This study was aimed to assay the antibacterial activity of compounds from Rabdosia rubescens. Disc dif-fusion (K-B method) was used to screen the in vitro antibacterial activity. All kinds of chromatography were used to isolate the chemical constituent and structure was identified by MS and NMR spectroscopy. The results showed that six compounds were isolated and identified as oridonin (1), rosmarinic acid (2), caffeic acid (3), salicylic acid (4), ferulic acid (5), vanillic acid (6). Oridonin had activity against Staphylococcus aureus (SA), Methcillin-resistant Staphylococcus aureus (MRSA), β-lactamase positive Staphylococcus aureus (ESBLs-SA), and showed the highest ac-tivity (MIC is 3.125, 6.25 and 6.25 μg·disc-1, respectively), but was still weaker than that of berberine as positive control (MIC is 0.156 μg·disc-1). Ferulic acid had activity against SA and MRSA (MIC is 50 and 50 μg·disc-1, re-spectively). Salicylic acid had only activity against SA (MIC 50 μg·disc-1). It was concluded that oridonin, ferulic acid and salicylic acid were the main antibacterial activity compounds from R. rubescens.
10.Comprehensive Classified Management of Hospital Drug Storeroom
Wei GUO ; Yin HUANG ; Peiyuan XIA ; Yongfu PENG
China Pharmacy 2007;0(31):-
80% defined as category A,B,and C,respectively.Category A drugs were regarded as the focus of management,category B as the second focus of management,category C underwent general management,category D drugs were regarded as the focus in purchase.RESULTS:Hospital first-order drug storeroom and secondary drug storerooms classified their drugs into their own A,B,and C categories (category D was consistent).The consumption sum of category A drugs(about 20% of drugs) accounted for 60%;the consumption sum of category B drugs(about 20% of drugs) accounted for 20%;and the consumption sum of category C drugs(about 60% of drugs) plus that of small quantity of category D drugs accounted for 20%.CONCLUSION:This method can ensure drug supply and help maximize ec-onomical benefits with least human,material and financial resources.