1.Follow-up study on patients with silicosis among rural workers from a county of Guangxi.
Xiao-Ping LI ; Wei-Ming ZOU ; Xian-Min GE
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(10):615-616
Adult
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China
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Follow-Up Studies
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Humans
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Middle Aged
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Mining
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Rural Population
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Silicosis
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mortality
7.Treatment for Gynura segetum caused hepatic vein occlusive disease: a single-center retrospective study
Yi WANG ; Yuzheng ZHUGE ; Feng ZHANG ; Ming ZHANG ; Wei ZHANG ; Qibin HE ; Xiaoping ZOU
Chinese Journal of Digestion 2016;36(12):811-815
Objective To explore the effects of different treatments on prognosis of patients with Gynura segetum caused hepatic vein occlusion disease (HVOD).Methods From July 2008 to January 2016,85 patients with Gynura segetum caused HVOD were enrolled and received treatment of liver function protection and microcirculation improvement.According to different treatment options,patients were divided into non-anticoagulation group,nowanticoagulation transfered to transjugular intrahepatic portosystem stent-shunt (TIPS) group,anticoagulation group,anticoagulation transfered to TIPS group and anticoagulation-TIPS step-by-step treatment group.The efficacy of each group was observed.Chi square test was performed for statistical analysis.Results Among 22 patients who received nonanticoagulation treatment,six (27.3%) patients were cured and 14 (63.6%) patients died during the treatment period;besides two (9.1 %) patients received TIPS because of ineffective treatment and achieved longterm survival.Among 63 patients treated with combination of low-molecular-weight heparin and warfarin,six (9.5%) patients died and 36(57.1%) patients were cured.The cure rate was higher than that of nonanticoagulation group (x2 =5.820,P=0.016).Other 21 patients received TIPS treatment,achieved longterm survival except one patient died from surgical complications.The cure rate of anticoagulation-TIPS step treatment group was 88.9 % (56/63) which was higher than that of non-anticoagulation group,and the difference was statistically significant (x2 =31.350,P<0.01).Conclusions Compared to conventional liver function protection treatment and symptomatic treatment,anticoagulation therapy significantly increases the cure rate of patients with Gynura segetum caused HVOD.Anticoagulation-TIPS step-by-step treatment further improves the cure rate.
8.A new procedure for repairing coronal or subcoronal hypospadias with severe chordee.
Chinese Journal of Plastic Surgery 2005;21(2):109-111
OBJECTIVETo introduce a new procedure for repairing coronal or subcoronal hypospadias with severe chordee.
METHODSA modified technique of elongating the anterior urethra, combined with the MAGPI procedure, was used to repair the coronal or subcoronal hypospadias in 19 severe chordee patients (aged 5 to 12 years). The fibrous bands on the ventral aspect of the penis were excised to correct the chordee. If the penile curvature still remained, the corpora cavernosa dissection and elongation could be applied.
RESULTSAll of the patients were successfully treated by this procedure in one stage.
CONCLUSIONSThe modified technique of the anterior urethra elongation, combined with MAGPI procedure, might be one of the simple and effective method for repairing coronal or subcoronal hypospadias with severe chordee.
Child ; Child, Preschool ; Humans ; Hypospadias ; surgery ; Male ; Penile Diseases ; surgery ; Penis ; surgery ; Urethra ; surgery
9.Immunophenotypic Features of NK/T Cell Lymphoma in Children and Its Association with Epstein-Barr Virus
wei-xing, GUI ; meng, MING ; da-bin, WANG ; dian-ding, ZOU ; jian-hua, YI ; jian, ZHANG
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To study the immunophenotypic features of NK/T cell lymphoma in children and its association with Epstein-Barr virus (EBV) infection. Methods Five cases of children′s NK/T cell lymphoma were studied. CD45RO, CD3?, CD56, CD20, TIA-1 and granzyme B were detected by immunohistochemistry staining for investigating immunophenotype. The expression of EBV-latent membrane protein (LMP-1) were detected by immunohistochemistry. EBV-encoded RNA (EBER1/2) were detected by in situ hybridization (ISH). Results CD45RO, CD3?, TIA-1 and granzyme B were positive in 5 cases, CD56 was positive in 2 cases, while CD20 negative in 5 cases.EBER1/2 positive in 4 cases and LMP-1 positive in 3 cases.Conclusions NK/T cell lymphoma in children is strong associated with EBV infection,and EBV infection may play an important role in the pathogenesis of children NK/T cell lymphoma.
10.Significance of Detection of Serum Cystatin C,Macrophage Migration Inhibitory Factor and Urinary Podocytes in Children with Primary Nephrotic Syndrome
min-shu, ZOU ; wei-xun, HE ; jian, YU ; guo-ming, NIE
Journal of Applied Clinical Pediatrics 1992;0(05):-
Objective To detect the level of serum cystatin C(CysC),macrophage migration inhibitory factor(MIF),urinary podocytes(UPC) and explore the correlation between the levels of the three and therapeutic effect in children with primary nephrotic syndrome(PNS).Methods The serum CysC,MIF levels were detected in 38 children with PNS,which were treated before and after remission by double-antibody sandwich sensitive enzyme-linked immunosorbent assay(ELISA).Podocyte-specific marker protein-Podocalyxin(PCX) was detected by immunofluorescene to definite UPC before and after remission and compare with those of healthy control group(n=15).Results Compared with control group,the levels of serum MIF were significantly increased in 22 patients responded sensitively to prednisone prior and post treatment(Pa0.05),however,CysC,MIF and UPC significantly increased after treatment in 16 steroid-resistant children(Pa0.05), MIF significantly decreased(Pa0.05)in steroid-resistant children after treatment.In 16 children with steroid-resistant, complete remission of PNS as cyclophosphamide pulse treatment being added in 10 patients,which CysC, MIF,UPC were significantly higher than those in control group(Pa