1.Survey on social support and demands for family caregivers of disabled elderly in Beijing Dongcheng District
Chenguang QIAN ; Wei XU ; Juan DU
Chinese Journal of General Practitioners 2015;14(11):838-843
Objective To survey the social support status and demands for family caregivers of the disabled elderly.Methods A cross-sectional survey based on convenience sampling was conducted among 779 disabled elderly and their family caregivers from May to June 2013 in five communities of Beijing Dongcheng District.Barthel index was used to measure the degree of functional impairment of the elderly.Self-rating Depression Scales (SDS) was used to evaluate depression symptoms of caregivers.Social Support Rating Scale (SSRS) and social support demand questionnaire were used to measure the social support status and social support demands of caregivers,respectively.Multiple linear regression analysis was used to analyze the influence factors of social support.Results Total 779 caregivers were identified and 744 caregivers completed the questionnaires with a valid response rate of 95.5%.Among 744 family caregivers the social support levels were low with an average SSRS score of 31.16 ± 6.86.There were significant differences in SSRS scores among caregivers of disabled elderly with different characteristics (age,married status and the Barthel index score) (all P < 0.05);and there were significant differences in SSRS scores among caregivers with different characteristics (age,educational level,married status,current employment,relationship with patients,caregiving time daily,subjective care burden,living with patients,number of caregivers and depression status) (all P < 0.05).Multiple linear regression analysis showed that the Barthel index score of the disabled elderly,the relationship with the elderly,depression status of the caregivers and the subjective care burden were correlated with the social support level of family caregivers (all P <0.05);the standard regression coefficients of above significant factors were 0.098,0.190,0.134 and 0.155,respectively.The social support demands of family caregivers were various;the average score was 2.44 ± 0.64,the top three demands were provision of care subsidy for the disabled elderly (average score was 2.95 ± 0.93),provision of care allowance for family caregivers (average score was 2.90 ± 0.93) and the guidance of safe medication (average score was 2.83 ± 0.83).Conclusions Family caregivers for the disabled elderly obtain low level social support in the surveyed area.Since the earegivers have various social support demands,the social support and assistance for them should be specific,effective and comprehensive.
2.Relationship between oxidative protein damage and serum matrix metalloproteinase-2 in diabetic nephropathy
Dailin WEI ; Juan XU ; Wenbo QI
Journal of Chinese Physician 2011;13(6):769-771,775
Objective Serum indicators of oxidative protein damage (OPD) were analyzed to explore the effect on renal MMP/TIMP system of OPD in diabetic nephropathy. Methods AOPP levels and PCO levels were measured by modified Witko-Sarsat's method and 2, 4-dinitrophenylhydrazine spectrophotometric method, expression of serum MMP-2 were determined by ELISA, and MMP-2 activity were detected by zymography . Results AOPP levels of group DN1, group DN2 were higher than those of group DM(78.23±19.30 vs 61.25±12.13,101.59±30.22 vs 61.25±12.13,F=41.988,P<0.01). PCO levels of group DN1 and group DN2 were higher than those of group DM (0.84±0.03 vs 0.66±0.02,1.05±0.05 vs 0.66±0.02,F=205.763,P<0.01). Pearson correlation analysis indicated AOPP and PCO were positively correlated with the expression (r=0.460,0.480,P<0.05) and activity (r=0.385,0.560,P<0.05) of serum MMP-2. Multiple stepwise regression analysis showed that AOPP and PCO were major influential factors of serum MMP-2 expression (P<0.05,P<0.01) and activity(P<0.01,P<0.05). Conclusions OPD might be involved in the imbalance of renal matrix metabolism, which was correlated with the development of diabetic nephropathy.
3.Imaging Diagnosis of Primary Bone Tumor and Tumor-Like Lesions of the Skull:An Analysis of 47 Cases
Juan YANG ; Shandan XU ; Jianjun BAI ; Longxiao WEI ; Zhenhe ZHUO
Journal of Practical Radiology 2001;0(05):-
Objective To explore the imaging features of primary bone tumors and tumor-like lesions of the skull,so that to improve the diagnostic accuracy of the disease.Methods 47cases with bone tumors and tumor-like lesions of the skull confirmed by pathology or typical imaging manifestations were retrospectively analysed.Results Of 47 cases,there were benign tumors in 22 cases,malignant tumors in 6 cases and tumor-like lesions in 19 cases.Benign tumors included osteoma of 11cases,epidermoid tumor and cyst of 4 cases,osteochondroma and neurofibromatosis of 2 cases respectively,carvernous angioma ,osteoid osteoma,and benign fibrohistiocytoma of 1case respectively.Malignant tumors included multiple myeloma and angiosarcoma of 2 cases respectively,Ewing’s tumor and osteosarcoma each and all in 1 case .Tumor-like lesions included fibrodysplasis of bone in 8 cases, Langerhans’ cell histiocytosis in 7 cases ,brown tumor and deformed osteitis each and all in 2 cases.Conclusion Primary bone tumor and tumor-like lesions of the skull are of a great variety,each one has its own imaging characteristics,the diagnosis of them should be combined with clinic and pathologic data.
4.Clinical analysis of digestive tract malignancies treated with iodine-125 interstitial brachytherapy.
Juan WANG ; Wei-Hong GONG ; Jian-Bin XU
Chinese Journal of Oncology 2008;30(2):153-154
Adult
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Aged
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Aged, 80 and over
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Brachytherapy
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adverse effects
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methods
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Digestive System Neoplasms
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radiotherapy
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Esophageal Neoplasms
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radiotherapy
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Female
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Fever
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etiology
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Follow-Up Studies
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Humans
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Iodine Radioisotopes
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therapeutic use
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Male
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Middle Aged
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Nausea
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etiology
5.Etiologic Analysis of Recurrent Abdominal Pain in Children
juan, MAI ; chun-di, XU ; wei, LIU ; zhao-hui, DENG
Journal of Applied Clinical Pediatrics 2004;0(07):-
Objective To investigate the characteristics of children′s recurrent abdominal pain(RAP) with gastroscopy and analyze the etiology.Methods Three hundred and thirteen children were investigated with gastroscopy.Gastric antrum mucosa was taken for histo-pathology and the determination of helicobacter pylori(Hp) antibody.Results Ninty-nine point six eight percent of the cases had lesions under the gastroscope.The former 4 cases had chronic superficial gastritis(CSG),CGS and bile reflux,CGS and duodenitis,CGS and bulb ulcer,and Hp infection rate was 31.36%,25%,38.64%,60.61%.Hp infection rates of active gastritis and inactive gastritis were 92% and 23.19%,which showed significant differences in 2 groups(P
6.Impact of community comprehensive intervention on healthy behavior and self-rated health status among family caregivers of disabled elderly
Wei XU ; Chenguang QIAN ; Xinmei LIU ; Li CHEN ; Juan DU
Chinese Journal of General Practitioners 2017;16(3):205-209
Objective To investigate the effect of community comprehensive intervention on health behavior and self-rated health status among family caregivers of disabled elderly.Methods One hundredand twenty family caregivers of disabled elderly were selected from community health service centers of Beijing Dongcheng District,and were given 6 month-comprehensive community intervention (intervention group);121 family caregivers of disabled elderly from another community were selected as the control group.The knowledge and skills of caregiving,health behaviors (daily exercise time,daily relaxation time) and self-rated health status were evaluated before and 6 months after intervention.Results The knowledge and skill scores in intervention group were improved by 50.781 points,the daily exercise time and daily relaxation time were prolonged by 0.491 h and 0.837 h,respectively after the intervention (all P<0.05).There was no significant difference in self-rated health status of two groups before and after intervention (P >0.05).Conclusion Community comprehensive intervention improves the knowledge and skills of caregiving,and the health behaviors among family caregivers of disabled elderly,but the intervention measures does not impact the self-rated health status of family caregivers.
7.Etiology and prevention of malocclusion after internal fixation in jaw bone fractures
Xu YAN ; Yan PENG ; Yu GAO ; Juan HU ; Haidong WEI
Journal of Practical Stomatology 1995;0(04):-
97 cases of jaw bone fractures were treated with rigid internal fixation.16 cases had malocclusion postoperation.The etiology was analyzed and the prevention methods were proposed.Intermaxillary elastic traction or fixation and craniomaxillofacial fixation or craniomentum elastic traction were performed to treat the malocclusion.By this way,14 cases were cured.1 case was operated again to resume the normal occlusion,1 case received occlusal adjustment.Incomplete reduction,incorrect operative performance,deficiency of postoperative intermaxillary fixation and incorrect intermaxillary fixation were the main causes to malocclusion.So anatomic in time reduction,correct operative performance,intermaxillary fixation,application of craniomaxillofacial fixation or craniomentum elastic traction instead of intermaxillary fixation for some special cases are effective methods to correct postoperative malocclusion.
8.Differences of Helicobacter Pylori Infection between Residents in Different Humidity Environment
Juan HU ; Wei LIN ; Yonghe HU ; Peng XU
Journal of Modern Laboratory Medicine 2015;(4):96-98
Objective To explore the differences of H .pylori infection between residents in different humidity environment. Methods 137 persons from Sanjiang of Wenchuan and 320 persons from Chengdu were examined.Blood samples were ob-tained for serological analysis by dot immunochromatographic assay.Results The infection rate of H .pylori in Wenchuan of Sanjiang residents was 26.28%,and the Chengdu rate was 16.88% (P <0.025),with the significant difference among which,and removed the effection of nation constitution.Conclusion The differences of H .pylori infection rate between res-idents in different humidity environment were existent.High humidity environment maybe one of factors that lead to high H.pylori infection rate.
9.Analysis on Variations of Serum Pepsinogen in Different Altitude Population
Juan HU ; Peng XU ; Yonghe HU ; Wei LIN
Journal of Modern Laboratory Medicine 2015;(3):32-34
Objective To compare the serum pepsinogen (PG)in different altitude population.Methods By testing serum PG of people from different altitudes,detected the concentration of serum PG.Results The serum PGI,serum PGII and PGR were respectively 136.89±22.64 μg/L,10.05 ± 5.14 μg/L and 13.07 ± 7.41 in 1 000 m group,and they were 30.87 ± 48.66 μg/L,11.55±2.78 μg/L and 12.89±4.76 in 1 300 m group.There were significant difference in PGI and PGII(P <0.05)except PGR (P >0.05)between the two groups.The corresponding indices in 1500m group (126.64±29.84 μg/L, 12.18±5.99 μg/L and 12.2±14.84,respectively),the serum PGI was decreased obviously compared with those groups (P<0.05),the serum PGII was increased obviously compared with those groups (P < 0.05),No significant difference was found when compared with those groups (P >0.05).The serum PGI was negative correlated with higher altitudes,the ser-um PGII was positively correlated with higher altitudes.Conclusion The study found that the serum PGI content would re-duce with the increase of altitude,and on the contrary the serum PGII would rise with the increase of altitude.The main rea-son that the serum PG change may be influenced by oxygen partial pressure.
10.Relationship between care burden and social support among family caregivers of disabled elders in Beijing urban area
Wei XU ; Chenguang QIAN ; Xinmei LIU ; Shuang SHAO ; Juan DU
Chinese Journal of General Practitioners 2015;14(2):87-89
Objective To explore the relationship between care burden and social support among family caregivers of disabled elders in Beijing urban area.Methods A cross-sectional survey based on convenience sampling was conducted among 744 family caregivers in Dongcheng District in Beijing urban area.All subjects were interviewed by the Zarit Burden Interview (ZBI),Social Support Rating Scale (SSRS) and general social and demographical material lists.And then we analyzed the correlation between social support and care burden.Results The mean scores of ZBT and SSRS were (40.3 ± 15.2) and (31.1 ± 6.9)respectively.And a negative correlation existed between the level of caregiver burden and total social support.The care burden of disability elders was negatively associated with objective support,subjective support and social support availability (P < 0.05).Conclusions There is a close relationship between care burden and social support among family caregivers of disabled elders.The more objective support,subjective support and social support availability the caregivers acquire,the less burden they bear.